KEGG   Escherichia coli K-12 MG1655: b2935
Entry
b2935             CDS       T00007                                 

Gene name
tktA
Definition
(RefSeq) transketolase 1
  KO
K00615  transketolase [EC:2.2.1.1]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00030  Pentose phosphate pathway
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01120  Microbial metabolism in diverse environments
eco01200  Carbon metabolism
eco01230  Biosynthesis of amino acids
Module
eco_M00004  Pentose phosphate pathway (Pentose phosphate cycle)
eco_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00030 Pentose phosphate pathway
    b2935 (tktA)
  09109 Metabolism of terpenoids and polyketides
   01051 Biosynthesis of ansamycins
    b2935 (tktA)
Enzymes [BR:eco01000]
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.1  transketolase
     b2935 (tktA)
SSDB
Motif
Pfam: Transketolase_N Transket_pyr Transketolase_C DXP_synthase_N E1_dh TPP_enzyme_C
Other DBs
NCBI-GeneID: 947420
NCBI-ProteinID: YP_026188
Pasteur: tktA
RegulonDB: ECK120001391
ECOCYC: EG11427
ASAP: ABE-0009625
UniProt: P27302
Structure
PDB: 

Position
complement(3079644..3081635)
AA seq 663 aa
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRF
VLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGI
ANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMMEGISHEVCSLAGTLKLGKLIA
FYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEAG
QAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASRKA
SQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINEDAAGNYIHYGVREFGMTAIANG
ISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQVA
SLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIARGG
YVLKDCAGQPELIFIATGSEVELAVAAYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESV
LPKAVTARVAVEAGIADYWYKYVGLNGAIVGMTTFGESAPAELLFEEFGFTVDNVVAKAK
ELL
NT seq 1992 nt   +upstreamnt  +downstreamnt
atgtcctcacgtaaagagcttgccaatgctattcgtgcgctgagcatggacgcagtacag
aaagccaaatccggtcacccgggtgcccctatgggtatggctgacattgccgaagtcctg
tggcgtgatttcctgaaacacaacccgcagaatccgtcctgggctgaccgtgaccgcttc
gtgctgtccaacggccacggctccatgctgatctacagcctgctgcacctcaccggttac
gatctgccgatggaagaactgaaaaacttccgtcagctgcactctaaaactccgggtcac
ccggaagtgggttacaccgctggtgtggaaaccaccaccggtccgctgggtcagggtatt
gccaacgcagtcggtatggcgattgcagaaaaaacgctggcggcgcagtttaaccgtccg
ggccacgacattgtcgaccactacacctacgccttcatgggcgacggctgcatgatggaa
ggcatctcccacgaagtttgctctctggcgggtacgctgaagctgggtaaactgattgca
ttctacgatgacaacggtatttctatcgatggtcacgttgaaggctggttcaccgacgac
accgcaatgcgtttcgaagcttacggctggcacgttattcgcgacatcgacggtcatgac
gcggcatctatcaaacgcgcagtagaagaagcgcgcgcagtgactgacaaaccttccctg
ctgatgtgcaaaaccatcatcggtttcggttccccgaacaaagccggtacccacgactcc
cacggtgcgccgctgggcgacgctgaaattgccctgacccgcgaacaactgggctggaaa
tatgcgccgttcgaaatcccgtctgaaatctatgctcagtgggatgcgaaagaagcaggc
caggcgaaagaatccgcatggaacgagaaattcgctgcttacgcgaaagcttatccgcag
gaagccgctgaatttacccgccgtatgaaaggcgaaatgccgtctgacttcgacgctaaa
gcgaaagagttcatcgctaaactgcaggctaatccggcgaaaatcgccagccgtaaagcg
tctcagaatgctatcgaagcgttcggtccgctgttgccggaattcctcggcggttctgct
gacctggcgccgtctaacctgaccctgtggtctggttctaaagcaatcaacgaagatgct
gcgggtaactacatccactacggtgttcgcgagttcggtatgaccgcgattgctaacggt
atctccctgcacggtggcttcctgccgtacacctccaccttcctgatgttcgtggaatac
gcacgtaacgccgtacgtatggctgcgctgatgaaacagcgtcaggtgatggtttacacc
cacgactccatcggtctgggcgaagacggcccgactcaccagccggttgagcaggtcgct
tctctgcgcgtaaccccgaacatgtctacatggcgtccgtgtgaccaggttgaatccgcg
gtcgcgtggaaatacggtgttgagcgtcaggacggcccgaccgcactgatcctctcccgt
cagaacctggcgcagcaggaacgaactgaagagcaactggcaaacatcgcgcgcggtggt
tatgtgctgaaagactgcgccggtcagccggaactgattttcatcgctaccggttcagaa
gttgaactggctgttgctgcctacgaaaaactgactgccgaaggcgtgaaagcgcgcgtg
gtgtccatgccgtctaccgacgcatttgacaagcaggatgctgcttaccgtgaatccgta
ctgccgaaagcggttactgcacgcgttgctgtagaagcgggtattgctgactactggtac
aagtatgttggcctgaacggtgctatcgtcggtatgaccaccttcggtgaatctgctccg
gcagagctgctgtttgaagagttcggcttcactgttgataacgttgttgcgaaagcaaaa
gaactgctgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (6)   
   KEGG MODULE (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (57)   

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