KEGG   Escherichia coli K-12 MG1655: b3266
Entry
b3266             CDS       T00007                                 
Symbol
acrF
Name
(RefSeq) multidrug efflux pump RND permease AcrF
  KO
K18142  multidrug efflux pump
Organism
eco  Escherichia coli K-12 MG1655
Module
eco_M00696  Multidrug resistance, efflux pump AcrEF-TolC
Brite
KEGG Orthology (KO) [BR:eco00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:eco02000]
    b3266 (acrF)
   01504 Antimicrobial resistance genes [BR:eco01504]
    b3266 (acrF)
Transporters [BR:eco02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   b3266 (acrF)
Antimicrobial resistance genes [BR:eco01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
    b3266 (acrF)
SSDB
Motif
Pfam: ACR_tran SecD_SecF MMPL
Other DBs
NCBI-GeneID: 947768
NCBI-ProteinID: NP_417732
Pasteur: acrF
RegulonDB: ECK120000261
ECOCYC: EG10267
ASAP: ABE-0010724
UniProt: P24181
Position
3415033..3418137
AA seq 1034 aa
MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT
VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ
EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA
QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF
KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL
DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ
NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY
LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN
EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG
FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL
EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM
LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM
ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV
MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV
EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF
VPVFFVVIRRCFKG
NT seq 3105 nt   +upstreamnt  +downstreamnt
atggcaaacttttttattcgacgaccgatatttgcatgggtgctggccattattctgatg
atggcgggcgcactggcgatcctacaattgcccgtcgctcagtatccaacaattgcaccg
cctgcggtttctgtttcagcaaactatccgggcgctgatgcgcagaccgtgcaggatacg
gtgacgcaggttatcgaacagaatatgaacggtatcgataacctgatgtatatgtcctcc
accagcgattccgccggtagcgtgacaattacccttaccttccagtccgggaccgatcct
gatatcgcgcaagtgcaggtgcagaacaaactccagctcgccacgccgttgctgccgcag
gaggttcagcagcaggggatcagtgttgaaaagtccagtagcagctatttgatggtggcg
ggctttgtctctgataacccaggcaccacacaggacgatatctcggactatgtggcctct
aacgttaaagatacgcttagccgtctgaatggcgtcggtgacgtacagcttttcggcgca
cagtatgcgatgcgtatctggctggatgccgatctgctaaacaaatataaactgacaccg
gttgatgtgattaaccagttgaaggtacagaacgatcagatcgctgccggacagttgggc
ggaacgccagcgttaccagggcaacaattgaacgcctcgattattgctcagacgcggttt
aaaaatccggaagaattcggcaaagtgaccctgcgcgtaaacagtgacggctcggtggta
cgcctgaaagatgtcgcacgggttgaacttggcggtgaaaactataacgttatcgctcgt
atcaacggaaaaccggcggcgggcctggggattaagctggcaaccggcgcgaatgctctc
gataccgcgaaagccattaaggcaaaactggcggaattacagccattcttcccgcaggga
atgaaggttctctacccttatgacaccacgccattcgtccagctttctattcacgaagtg
gtaaaaacgctgttcgaagccattatgctggtgttcctggtgatgtatctgttcttgcag
aatatgcgagcaacgctgatccccaccattgcggtacccgtggtgttgttagggacgttt
gccatcctcgccgcttttggttactccatcaacacactaacgatgttcgggatggtgctt
gccatcgggctgctcgtcgatgatgcgatagtggtggtggagaacgtcgagcgcgtgatg
atggaggataagctcccgccaaaagaagcgacggaaaaatcgatgtcgcaaattcagggc
gcactggtgggtatcgcgatggtgctgtcagcggtatttattccgatggcattcttcggc
ggttctactggggcaatttatcgccagttctctatcaccatcgtttcggcaatggcgctt
tctgttctggtggcattgattcttacccctgcgttatgtgcaacgctgcttaaacccgtc
tctgctgagcatcacgaaaataagggcggtttcttcggttggtttaataccaccttcgat
catagcgttaaccactacaccaacagcgtcggcaaaatcctcggatccacaggacgatat
ttactgatctatgcgctgattgttgcaggaatggtggtgttgtttttacgtcttccgtct
tccttcttacctgaagaggatcagggtgtctttctgaccatgattcagttacccgctggc
gcgacgcaagagcggacgcaaaaagtgttggatcaagttacggattactatctgaagaac
gagaaagcgaacgttgaaagtgtctttacggttaacggctttagcttcagcggccaggca
caaaacgccggtatggccttcgtcagtctgaaaccgtgggaagagcgtaatggtgacgaa
aacagtgcggaagcggtaatccatcgtgccaaaatggaattgggcaagatccgcgacggt
tttgtcattccattcaatatgccagccattgttgaactgggcacggcaacgggtttcgac
tttgagttaattgatcaggctgggctgggtcacgatgccctaacccaggcccgtaaccag
ttgcttggtatggcggcgcaacatcctgccagcttagtcagcgtgcgccctaatggcctg
gaagacaccgcgcagtttaaactggaagttgaccaggaaaaggcgcaggcattaggtgtt
tcactttctgacatcaatcagaccatttcaacggcgctgggtgggacttacgttaacgac
ttcatcgaccgtggccgcgtgaaaaagttgtatgttcaggcggatgccaaattccgtatg
ctgccagaagatgtcgataaactttatgtccgcagcgccaacggcgaaatggtgccattc
tcggcctttaccacttcacattgggtgtatggctctccgcgactggaacgctacaacggt
ctgccgtcaatggagattcagggggaagccgcgccaggaaccagttccggcgatgccatg
gcgttgatggaaaaccttgcgtcaaaattacctgcgggcattggttatgactggacgggt
atgtcgtatcaggaacgcttatcgggaaaccaggctcccgctctggtagcaatttccttt
gtggttgttttcctgtgccttgctgcactctatgaaagctggtcaattcctgtctcggtt
atgttggtagtgccgttagggattgtcggcgtgctgctggcggcgacactctttaatcaa
aaaaatgacgtctactttatggtgggcttgctaacgacaattggcttgtcggccaaaaac
gctattttgatcgttgagttcgctaaagatctcatggagaaagagggtaaaggtgttgtt
gaagcgacactgatggcagtacgtatgcgtctgcgtcctatcctgatgacctctctcgcc
tttattctcggcgtattaccgctagctatcagtaacggtgccggcagtggcgcgcagaac
gctgtgggtatcggggtaatgggaggaatggtctctgcaacgttgctggcaatcttcttc
gtaccggtgttctttgtggtgatccgccgttgctttaaaggataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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