KEGG   Escherichia coli K-12 MDS42: ECMDS42_0362
Entry
ECMDS42_0362      CDS       T02541                                 
Symbol
acrA
Name
(GenBank) multidrug efflux system
  KO
K03585  membrane fusion protein, multidrug efflux system
Organism
ecok  Escherichia coli K-12 MDS42
Pathway
ecok01501  beta-Lactam resistance
ecok01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:ecok00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    ECMDS42_0362 (acrA)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    ECMDS42_0362 (acrA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ecok03036]
    ECMDS42_0362 (acrA)
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ecok02000]
    ECMDS42_0362 (acrA)
   01504 Antimicrobial resistance genes [BR:ecok01504]
    ECMDS42_0362 (acrA)
Chromosome and associated proteins [BR:ecok03036]
 Prokaryotic type
  Chromosome partitioning proteins
   Divisome proteins
    ECMDS42_0362 (acrA)
Transporters [BR:ecok02000]
 Other transporters
  Accessory factors involved in transport [TC:8]
   ECMDS42_0362 (acrA)
Antimicrobial resistance genes [BR:ecok01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    ECMDS42_0362 (acrA)
SSDB
Motif
Pfam: CusB_dom_1 HlyD_D23 HlyD_3 Biotin_lipoyl_2 OEP EAD11
Other DBs
NCBI-ProteinID: BAL37669
Position
complement(392169..393362)
AA seq 397 aa
MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVTVKTEPLQITTELPGRT
SAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDSAKGDLAKAQAAAN
IAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLAYTKVTSPI
SGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQSSNDFLRLKQELANGTLKQENG
KAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEG
LNPNAILVPQQGVTRTPRGDATVLVVGADDKVETRPIVASQAIGDKWLVTEGLKAGDRVV
ISGLQKVRPGVQVKAQEVTADNNQQAASGAQPEQSKS
NT seq 1194 nt   +upstreamnt  +downstreamnt
atgaacaaaaacagagggtttacgcctctggcggtcgttctgatgctctcaggcagctta
gccctaacaggatgtgacgacaaacaggcccaacaaggtggccagcagatgcccgccgtt
ggcgtagtaacagtcaaaactgaacctctgcagatcacaaccgagcttccgggtcgcacc
agtgcctaccggatcgcagaagttcgtcctcaagttagcgggattatcctgaagcgtaat
ttcaaagaaggtagcgacatcgaagcaggtgtctctctctatcagattgatcctgcgacc
tatcaggcgacatacgacagtgcgaaaggtgatctggcgaaagcccaggctgcagccaat
atcgcgcaattgacggtgaatcgttatcagaaactgctcggtactcagtacatcagtaag
caagagtacgatcaggctctggctgatgcgcaacaggcgaatgctgcggtaactgcggcg
aaagctgccgttgaaactgcgcggatcaatctggcttacaccaaagtcacctctccgatt
agcggtcgcattggtaagtcgaacgtgacggaaggcgcattggtacagaacggtcaggcg
actgcgctggcaaccgtgcagcaacttgatccgatctacgttgatgtgacccagtccagc
aacgacttcctgcgcctgaaacaggaactggcgaatggcacgctgaaacaagagaacggc
aaagccaaagtgtcactgatcaccagtgacggcattaagttcccgcaggacggtacgctg
gaattctctgacgttaccgttgatcagaccactgggtctatcaccctacgcgctatcttc
ccgaacccggatcacactctgctgccgggtatgttcgtgcgcgcacgtctggaagaaggg
cttaatccaaacgctattttagtcccgcaacagggcgtaacccgtacgccgcgtggcgat
gccaccgtactggtagttggcgcggatgacaaagtggaaacccgtccgatcgttgcaagc
caggctattggcgataagtggctggtgacagaaggtctgaaagcaggcgatcgcgtagta
ataagtgggctgcagaaagtgcgtcctggtgtccaggtaaaagcacaagaagttaccgct
gataataaccagcaagccgcaagcggtgctcagcctgaacagtccaagtcttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (6)   
   Pfam (6)   
All databases (17)   

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