KEGG   Enterococcus faecalis V583: EF1577
Entry
EF1577            CDS       T00123                                 
Symbol
folA
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
efa  Enterococcus faecalis V583
Pathway
efa00670  One carbon pool by folate
efa00790  Folate biosynthesis
efa01100  Metabolic pathways
efa01240  Biosynthesis of cofactors
Module
efa_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:efa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    EF1577 (folA)
   00670 One carbon pool by folate
    EF1577 (folA)
Enzymes [BR:efa01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     EF1577 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 1200477
NCBI-ProteinID: NP_815294
UniProt: Q834R2
Structure
Position
1530013..1530507
AA seq 164 aa
MLAAIWAQDEQGVIGKEGKLPWHLPNDLKFFKEKTIHNTLVLGRATFEGMGCRPLPNRTT
IVLTSNPDYQAEGVLVMHSVEEILAYADKYEGVTVIGGGSVVFKELIPACDVLYRTMIHE
TFEGDTFFPEIDWSVWEKVATVPGVVDEKNLYAHDYETYHRNDK
NT seq 495 nt   +upstreamnt  +downstreamnt
atgttagcagccatttgggcccaagatgaacaaggagtgattggtaaagaaggcaaattg
ccttggcatttacccaacgacttgaaatttttcaaggaaaaaacaattcataatacattg
gttttaggacgtgcaactttcgaaggtatgggatgtcgtccgttaccaaatcgaacaacg
attgttcttaccagtaatccggattaccaagctgaaggcgttttggttatgcattccgta
gaggaaattcttgcgtatgctgacaagtatgaaggcgtgaccgttattggtggaggttct
gtcgtttttaaagaattgattcccgcatgcgatgtcttatatcggacgatgattcatgaa
acgtttgaaggcgacaccttctttccagaaatcgactggtctgtttgggaaaaagttgcc
actgttcccggcgtcgtggacgagaaaaatctctatgcacatgactatgaaacgtatcat
cgaaacgataaataa

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