KEGG   Escherichia fergusonii: EFER_0518
Entry
EFER_0518         CDS       T00811                                 
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
  KO
K01952  phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
Organism
efe  Escherichia fergusonii
Pathway
efe00230  Purine metabolism
efe01100  Metabolic pathways
efe01110  Biosynthesis of secondary metabolites
Module
efe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:efe00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    EFER_0518 (purL)
Enzymes [BR:efe01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.3  phosphoribosylformylglycinamidine synthase
     EFER_0518 (purL)
SSDB
Motif
Pfam: GATase_5 AIRS_C FGAR-AT_N FGAR-AT_linker
Other DBs
NCBI-ProteinID: CAQ88066
UniProt: B7LV08
Position
516020..519907
AA seq 1295 aa
MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
HEQWQQVTAELHDRMMETVFSALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGSEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLVVTLAEMAFA
GHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFNESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq 3888 nt   +upstreamnt  +downstreamnt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggtaaactcctgctggtgaccccgcgt
cctggtaccatctctccctggtcttcgaaagcgaccgatatcgcccataactgcgggctg
caacaggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
catgaacaatggcagcaggtgaccgctgaactgcacgaccgcatgatggaaacggtcttt
tctgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcgctggcggaagatgaaattgactatctgcaggatgcgttcacaaagctgggtcgtaac
ccgaacgacatcgagctgtatatgttcgcccaggcgaactctgagcactgccgtcataaa
atttttaacgccgactggattatcgacggtgaacagcaaccgaaatcgctgttcaagatg
atcaaaaataccttcgaaaccacgccggatcacgttctttctgcttataaagataacgcc
gccgtgatggaaggttccgaagtgggccgctactttgctgaccacgaaacgggccgctac
gacttccatcaggaaccggcgcacatcctgatgaaagtagaaacccacaaccacccaacg
gcgatttctccgtggccgggcgcagctaccggttccggcggtgaaatccgcgatgaaggt
gccaccggccgcggcgcgaagccgaaagctggcctggtcggtttctccgtatccaacctg
cgtattcctggctttgaacaaccgtgggaagaagatttcggtaagcctgagcgcattgtc
actgcgctggatatcatgaccgaaggcccgctgggcggcgcggcatttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacctatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcgggtatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaaactggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcctcttccatggcctccggccag
tctgacgcggatctcgatttcgcgtccgttcagcgcgataacccggaaatggaacgtcgt
tgccaggaagtgatcgaccgctgctggcagcttggcgacgcgaacccgattctgtttatc
cacgacgtcggcgcaggcggtctttctaacgccatgccggagctggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaatgaatcccaggaacgctacgtgctggcagttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcaccgtacgcggtgattggtgaggcc
accgaagaattacatctttctctgcacgatcgtcattttgataatcaacccatagatcta
ccgctcgacgtactgcttggcaaaacgccgaagatgacccgcgatgtgcaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgtgtg
ttacatctgccgactgtggcggagaaaacctttctggtgaccatcggcgatcgcagcgta
accggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcagtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgaacgt
gcgccggttgcgctgctggatttcgctgcctctgctcgtctggcggttggtgaagcgtta
actaacattgccgcaacgcagattggcgatatcaaacgcatcaaactttccgccaactgg
atggcagcagcaggtcatccaggtgaagacgcgggcctgtatgaagccgttaaagcggtg
ggcgaagagctttgcccggcgctgggcctgactatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtagcgaagagcgcgaaatgacctcgccgctttcgctg
gtgatttctgcatttgcccgcgtggaagatgtgcgtcacaccatcacgccgcagctttct
accgaagataacgcactgctgctgattgatctgggcaaaggcaataacgcgctgggtgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtc
gcgcaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctc
gcgtatcacgaccgctctgatggcgggctggtggtaacgctggcggaaatggcctttgct
ggtcattgcggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggggcggtgattcaggtgcgcgctgctgaccgtgaagcggtcgaa
gcggtactggcacagcatggccttgctgattgcgtccattatgttggtcaggcggtttcc
ggtgaccgttttgtaattaccgccaacgggcagactgtattcaacgaaagccgcaccacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggaacatcaggcgaaatctaacgacgccgatccgggcctgaatgtgaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtatattgccaccggtgcgcgtccg
aaagttgccgtgctgcgtgagcagggtgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggcttcgatgcaatcgatgtgcatatgagcgacctgctggctggacgcacg
ggcctggaggatttccacgctctggtagcgtgcggcggtttctcctacggtgatgtgctg
ggtgctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccgggtagcgagttgtggccacgtttcgtgcgtaac
acctccgatcgctttgaagcgcgtttcagcctggtagaagtgacacaaagcccgtcgctg
ctgttgcaagggatggtgggttcgcagatgccgattgctgtctctcacggcgaagggcgc
gtggaagtgcgcgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaatggtattacggcggtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagtaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgtattttccgcaatgcgcgtaagcagttggggtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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