KEGG   Enhydra lutris kenyoni (northern sea otter): 111140006
Entry
111140006         CDS       T05871                                 
Name
(RefSeq) serine/threonine-protein kinase ULK1
  KO
K21357  serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
Organism
elk  Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04137  Mitophagy - animal
elk04140  Autophagy - animal
elk04150  mTOR signaling pathway
elk04152  AMPK signaling pathway
elk04211  Longevity regulating pathway
elk05010  Alzheimer disease
elk05014  Amyotrophic lateral sclerosis
elk05016  Huntington disease
elk05017  Spinocerebellar ataxia
elk05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:elk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    111140006
   04150 mTOR signaling pathway
    111140006
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    111140006
   04137 Mitophagy - animal
    111140006
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    111140006
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111140006
   05014 Amyotrophic lateral sclerosis
    111140006
   05016 Huntington disease
    111140006
   05017 Spinocerebellar ataxia
    111140006
   05022 Pathways of neurodegeneration - multiple diseases
    111140006
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:elk01001]
    111140006
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:elk04131]
    111140006
   03029 Mitochondrial biogenesis [BR:elk03029]
    111140006
Enzymes [BR:elk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     111140006
Protein kinases [BR:elk01001]
 Serine/threonine kinases: Other
  ULK family [OT]
   111140006
Membrane trafficking [BR:elk04131]
 Autophagy
  Autophagosome formation proteins
   ULK complex
    111140006
Mitochondrial biogenesis [BR:elk03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    111140006
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ATG1-like_MIT2 ATG1-like_MIT1 Kdo ABC1 RIO1 Pkinase_fungal Kinase-like
Other DBs
NCBI-GeneID: 111140006
NCBI-ProteinID: XP_022348107
UniProt: A0A2Y9IHJ0
Position
Unknown
AA seq 1052 aa
MEPGRGGLEAVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL
GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTIRLFLQ
QIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPNNIRVKIADFGFARYLQSNMMAAT
LCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYERNKTLV
PTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASATVKKSPPVPVPSYPSSGS
GSSSSSSSASHLASPPSLGEMQQQLQKTLTSPADGGFLQGSRGSGGSSKDSSCDTDDFVM
VPAQFPGDLVAEAAGAKPPPDSLMCSGSSLVASAGLESRGRTPSPSPPCSSSPSPSGRAG
PFSSRCGVSVPIPVPTQVHNYQRIEQNLQSPTQYQTTRSSAIRRSGSTSPLGFARPSPSP
PSYAEHGTTLARKLSLGGGRPYTPSPQVGILPERPGWSGAPSPQGAEMRGGRSPRPGSSA
PEHSAHAAGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGVAFGHPQSSPPQPAHGLQSCR
PLRGSPKLPDFLQRNPLPPILGSPTKAMPAFDFPKTPSSQNLLALLARQGVVMTPPRNRT
LPDLSEAGPFQGPQLGPGLRPAEDKSPFGRSLSTGRLTDLLLKAAFGTQAPDSGSTDSLQ
EKPMEIAPSAGLGGNLHPGARAGGASSPSPVVFTVGSPPSGTTPPQGPRARVFSVGSSSS
LGSAGSSSARHLPPGACGEGAPDAPAPGHCCGFADPVTANLEGAVTFEAPDLPEETLMEQ
EHTEILHSLRFTLVFVQHVLEIAALRGSASDTAGGPESQLQESVVADQISLLSQEWGFAE
QLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRKLNELYKASVVSCQGLSLRLR
RFFLDKQRLLDRIQSVTAEKLIFSHAVQTVQSAALDEMFHRREDCVQRYHKALLLMEGLQ
HILSDQADVENIAKCKLCIERRLSALLSGLCA
NT seq 3159 nt   +upstreamnt  +downstreamnt
atggagcccggccgcggcggcctggaggccgtgggcaagttcgagttctcgcgcaaggac
ctgatcgggcacggcgccttcgccgtggtcttcaaggggcgccatcgggagaagcatgac
ctggaggtcgcggtcaaatgcattaacaaaaagaacctggccaagtcccagacactgctg
gggaaggaaatcaagatcctcaaggaattgaaacatgaaaacatcgtggctttgtatgac
ttccaggagatggccaattctgtttacctggtcatggagtactgtaacggcggggacctg
gccgactacctgcacaccatgcggacgctgagcgaggacaccatccggctcttcctgcag
cagatcgcgggcgccatgcgtctgctgcacagcaaaggcatcattcaccgggacctgaag
ccccagaacatcttgctgtccaaccctggtgggcgccgcgccaaccccaacaacatccgc
gtcaagatcgccgacttcgggttcgctcggtacctgcagagcaacatgatggcggccacg
ctgtgcggctcccccatgtacatggcccccgaggtcatcatgtcccagcattacgacggg
aaggcggacctgtggagcatcggcaccatcgtgtaccagtgcctgacggggaaggcgccc
ttccaggccagcagcccccaggaccttcgcctcttctacgagaggaacaagacgctggtc
cccaccatccccagggagacgtcagccccgctgagacagctgctgcttgccctgctgcag
cggaaccacaaggaccgcatggacttcgacgagttcttccatcatcctttcctcgacgcc
agcgccactgtgaagaagtcccctcccgtgcctgtgccctcgtacccgagctcgggctcc
ggcagcagctccagcagcagctccgcctcgcacctggcctccccgccgtccctgggagag
atgcagcagcagctgcagaagacgctgacgtccccggccgacggtggcttcctgcagggc
tcccgtggctctggtggcagcagcaaggactcatcctgcgacacggacgacttcgtcatg
gtcccggcccagtttccaggtgacctggtggctgaggcagctggtgccaagcctcctccg
gacagcctcatgtgtagcgggagctcactggtggcttctgctggcctggagagccgtggc
cggaccccatctccttccccgccctgcagtagctctcccagcccctcaggccgggccggc
cccttcagcagcaggtgcggcgtgtccgtccccatcccagtccccacgcaggtgcacaac
taccagcgcattgagcagaatctgcagtcgcctacccagtaccagaccacacggtcctcc
gccatccgcaggtcaggcagcaccagccccctgggctttgcccgccccagtccgtccccg
ccgtcctacgctgagcacggcaccaccttggccaggaagctgtccctgggagggggccgg
ccctatacaccgtctccacaagttggaatcctccccgagcggcctggctggagcggggca
ccctccccgcaaggagccgagatgcggggaggcagatcccctcgtccgggctcctctgca
ccggagcactctgcgcatgctgctgggctgggctgtcgcctgcacagcgctcccaacctg
tccgacctgcacgtcgtccgccctaagttgcccaagccccccacggaccccctgggggtg
gcattcggccacccccagtccagccccccacagccggcccacgggctacaatcctgccga
cccctgcgaggctcacccaagctgcctgacttcctgcagcgcaaccccctgcccccaatc
ctcggctcccccaccaaggccatgcctgccttcgacttccccaagacccccagctcccag
aacttgctggccctcctggcccggcagggtgtggtcatgaccccgccacggaaccggacg
ctgccggacctctccgaggcaggaccgttccaggggccacagctgggccccggcctgcgg
cccgccgaggacaagagcccctttggcaggtccctcagtactggccgcctcactgatctg
ctccttaaggctgcgtttgggacccaggcccctgactcggggagcacggacagcctgcag
gagaagcctatggagatcgcgccctctgctggcctcggagggaacctgcacccaggagcc
cgtgctgggggggccagcagcccgtctcccgtggtgttcactgtgggctcgccccccagc
gggaccacgccaccccagggtccccgtgccagggtgttctcagtgggctcctcgagttcc
cttggctctgccggctcctcctctgcccgtcacctgccccccggggcctgtggggagggt
gccccggacgctccggcccctggccactgctgcggctttgccgaccctgtcaccgccaac
ctggagggggctgtgaccttcgaggcccccgatctccctgaggagacgctgatggagcaa
gagcacacggagatcctgcacagcctgcggttcacgctggtctttgtccagcacgtgctg
gagatcgcggccctgagaggcagcgccagcgacacagccggggggcctgagtcgcagctg
caggagagcgtggtggccgaccagatcagcctgctgagccaggagtggggctttgcggag
cagctggtgctctacctgaaggtggctgagctgctgtcctcgggcctgcagaccgccatc
gaccagatccgggccggcaagctgtgcctgtcttccaccgtgaagcaggtggtgcggaag
ctgaacgagctgtacaaggcgagcgtggtgtcctgccaagggcttagcctgcggctgcgg
cgcttcttcctggacaagcagcggctgctagaccgcatccagagtgtcaccgccgagaag
ctcatctttagccacgcggtgcagacggtgcagtctgccgccttggacgagatgttccac
cgtcgggaggactgcgtgcagcgctaccacaaggccctgctgctcatggaggggctgcag
cacatcctcagcgaccaggcggatgtggagaacatcgccaagtgcaagctgtgcatcgag
cggagactctcggcgttgctgagcggcctctgtgcctga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (32)   

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