KEGG   Esox lucius (northern pike): 105027310
Entry
105027310         CDS       T04894                                 
Name
(RefSeq) melanoma receptor tyrosine-protein kinase
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
els  Esox lucius (northern pike)
Pathway
els04010  MAPK signaling pathway
els04012  ErbB signaling pathway
els04020  Calcium signaling pathway
els04068  FoxO signaling pathway
els04144  Endocytosis
els04510  Focal adhesion
els04520  Adherens junction
els04540  Gap junction
els04810  Regulation of actin cytoskeleton
els04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:els00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105027310
   04012 ErbB signaling pathway
    105027310
   04068 FoxO signaling pathway
    105027310
   04020 Calcium signaling pathway
    105027310
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    105027310
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105027310
   04520 Adherens junction
    105027310
   04540 Gap junction
    105027310
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105027310
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    105027310
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:els01001]
    105027310
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:els04147]
    105027310
Enzymes [BR:els01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     105027310
Protein kinases [BR:els01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   105027310
Exosome [BR:els04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   105027310
  Exosomal proteins of pancreatic cancer cells
   105027310
  Exosomal proteins of bladder cancer cells
   105027310
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Haspin_kinase Kinase-like Kdo
Other DBs
NCBI-GeneID: 105027310
NCBI-ProteinID: XP_010897658
Position
LG21:9065103..9101202
AA seq 1184 aa
MRPETGIVIAALLSLSCCITLTADKKVCQGTSNKLTQLGTEDEHYNSMVRMYSNCSVVLE
NLELTYTQDYHDLTFLKSIQEVGGYVLIAYNNAANISLENLRLIRGHSVFQDKYALVVMS
NYKKKDSSVSLSYIGGLRELRLTGLTEILKGGVKFSHNLFLCNVDTIQWWDILNKPSSPR
IDLKLETNPYCDKCDPGCYNGSCWAPGPENCQTFTKLTCPDQCSGRCRGPKPSDCCNEHC
AAGCTGPRPTECLACRDFQDDDTCKDTCPPIMLYNPTTHQLASNPNAKYTFGATCVKTCP
HNYVVTDQGACVRTCSDNTHEVEENGVRRCKKCDGICPKVCNGLGTGQLTNVLTVNGSNI
DSFENCTKINGDVSIIETSLNGDNYTSTPKMDPNKLEYFKTVKEISGFLLIQAWPKHLNS
LSPFENLEIIRGRTKQFGQVSFAVLKVDHLKYLGLRSLREISDGNVVVKNNRQLCYTNED
HWKGLFRMEKQTSKIGNNANISTCAQMNSTCDEMCTAKGCWGPGPTMCFSCQHYSREGRC
VGACQILEGVPREYVVNNTCMGCDQECMVKNGTQSCFGPGPDKCLACAHFKDGPNCVSRC
PHGVPGDGDRQIWKFPDRKRECQLCHENCTQGCSGPGLSGCNIKGGHVPSVVAVSVVGGL
LVFVILALGVFVLFRRRSIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKK
IKVLGSGAFGTVFKGVWIPEGESIKIPVAIKVLREATSPKANREILDEAYVMASVEHPHV
CRLLGICLTSTVQLITQMMPFGCLLDYVKENKDHIGSQCLLNWCVQIAKGMNYLEERHLV
HRDLAARNVLVKTPHHVKITDFGLAKLLTANEKEYHADGGKVPIKWMALESILHWTYTHQ
SDVWSYGVTVWELMTFGSKPYDGIPATEIAGVLERGERLSQPPICTIDVYMIMVKCWMID
ADSRPRFRELIAEFSKMARDPSRYLVIQGDDRMYLPSPTDSKFYRTLLSTSGDTGDVVDA
EEYLLPYKVLPNGPTENHNSGNCQLMRENSVTLRYITDPTHGGSMEKCFPFPPEYINQNG
SRRLSDVFNPNYEDPSEQVWCIRRSSWDNQDVKVPSILPRVPEGPEYLNTGRSTLPRSFG
ESMDNPDYQECFLPPATPTTSHFLPAAENLEYLGLSAPVHAPVR
NT seq 3555 nt   +upstreamnt  +downstreamnt
atgcgacctgaaactggaattgttatcgctgccttgttaagcctgagctgctgcataact
ctgacagcggacaagaaagtgtgtcaaggaaccagcaacaagctgactcagcttggcact
gaagacgagcactacaacagcatggtgaggatgtacagtaactgtagcgtggtcctggag
aacctagagctgacctacacccaggactaccacgacctgacattcctcaagtctattcag
gaagttggaggctatgttctgatcgcctacaacaatgcagccaatatctctctggagaac
ctgcgtcttatccgaggacattccgtcttccaggacaaatacgccctggttgtcatgtcc
aactacaagaagaaagactcctctgttagcctcagctacatcggggggttgcgggagctg
cgactgaccgggctgacagagattctcaaggggggggtgaaattctcccacaatctgttt
ctgtgtaatgtggacaccatccagtggtgggacatactgaacaagcccagcagccccaga
atagacttgaaactggagaccaatccgtattgcgacaagtgtgaccctgggtgctacaat
ggatcgtgctgggcgccaggaccagagaactgccaaacctttaccaagctaacatgtcca
gatcagtgctctggaaggtgtaggggtccaaaacccagtgattgttgtaatgaacactgt
gctgctggctgcaccggaccccgacctacagaatgtctggcctgcagagactttcaggac
gacgacacctgtaaggacacctgcccccctattatgctttacaatccaaccacccaccag
ctggcttctaaccctaacgccaagtacacgttcggggccacgtgtgtgaagacctgccca
cataactacgtggtgacggaccagggggcgtgtgtcagaacgtgcagcgacaacacacac
gaggtggaggagaatggcgtgaggaggtgcaagaagtgtgatgggatctgtccaaaagtt
tgtaatggacttggaacggggcaactcactaatgtcttgacagtcaatggatctaacatt
gattcttttgaaaactgcaccaaaatcaacggagatgtatccataattgagacatctttg
aacggtgataattacacatcaacaccaaaaatggacccaaacaaactggaatatttcaaa
actgtcaaggaaatttcgggatttctgctgatacaagcttggcctaagcacctcaactcc
ctcagtccatttgaaaaccttgagatcatcagaggaaggactaaacagtttggtcaggtc
agtttcgccgtcctcaaagtggatcatctgaagtatttaggcctccgctccctacgagag
ataagcgatggcaacgtcgtggtgaagaacaaccgccagctctgctacaccaatgaagac
cactggaagggcctgttcagaatggaaaaacaaacctcaaaaataggcaacaatgcaaac
attagcacctgtgcccagatgaacagtacctgtgatgaaatgtgcacggccaagggctgc
tgggggcccggtccaaccatgtgtttcagctgccagcactacagccgcgagggccgctgt
gtgggcgcctgccaaatactggagggcgtgccacgagagtatgtcgtgaataacacgtgc
atggggtgtgaccaagaatgcatggtgaagaatggaacccaaagctgttttggaccgggc
cctgacaagtgtctagcatgtgcccacttcaaagatggccccaactgtgtcagtcggtgc
ccacacggcgtgcctggagacggggataggcaaatctggaaatttcctgacaggaagaga
gaatgtcagctctgccatgagaactgcacccagggatgctctggacctggcttgagtggt
tgcaacatcaaaggtggtcatgtcccttcagtggtggcggtcagcgtggtgggaggcctg
ctggtcttcgtgatcctggccctgggtgtctttgtcctgttccgcagacgctccattgtc
aggaagaggacgctgcgccggctgctgcaagagagagagttggttgagcccctgacccca
agtggcgaagcacccaaccaggccctgcttcgcatcctgaaggagaccgagtttaaaaag
atcaaagtgttgggatcaggagcattcggaactgtctttaagggtgtgtggattcctgag
ggagaaagcataaagatcccggttgcaatcaaggtgttgagagaggccacgtcacccaaa
gccaacagggagattctggacgaggcctatgtgatggccagtgtggagcacccccacgtg
tgtcgtctgttgggcatctgcctgacctccacggtgcagctcatcacccagatgatgccc
tttggctgcctgctggactacgtcaaggagaacaaggaccacatcggctcccagtgcctg
ctcaactggtgcgtgcagatcgccaaggggatgaactacctggaggagcgtcacctggtt
caccgcgacctggcggccaggaacgttttggtgaagacgcctcaccatgtcaagatcacc
gacttcggactggccaagctgctgactgccaacgagaaggagtaccacgctgacgggggc
aaggttcccattaagtggatggccctggaatccatacttcactggacctacacccaccag
agcgacgtgtggagctacggtgtcacggtgtgggagctgatgacgttcgggtccaagccc
tacgatggcatcccggccacggagatcgctggcgtcctggagagaggagaacgcctgtcc
cagccccccatctgtaccatagacgtctacatgatcatggtcaaatgctggatgattgat
gctgacagcagaccgcggttcagggagttaattgctgagttctccaagatggctcgggat
ccgtctcgctacctggtcattcagggagacgatcgcatgtacctgccaagtccaacggac
tccaagttctaccggaccctgcttagtacatcaggtgacactggagatgtagtggatgct
gaggagtaccttcttccctataaggtcttacccaatgggcccactgagaaccacaactct
gggaattgccaactaatgcgagagaacagtgtgacccttcgttacatcactgaccccacc
catgggggctcgatggagaagtgtttccccttccctccagaatacatcaaccagaacggg
agccgcaggctttcggacgtcttcaatcccaactacgaggatcccagcgagcaggtctgg
tgtattaggcgctcctcttgggacaaccaggatgttaaggtacccagcattctgccgcgt
gtcccagaggggccagagtacctcaacacaggccgcagtaccctccctcgctcctttggt
gagagtatggacaacccagattaccaggaatgctttctgcccccggccacacccaccaca
agccacttcctgcctgcagcagaaaacctggagtaccttggcttgagcgctcctgtgcac
gcccctgtacgctag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (38)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (71)   

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