KEGG   Esox lucius (northern pike): 105030222
Entry
105030222         CDS       T04894                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
els  Esox lucius (northern pike)
Pathway
els04010  MAPK signaling pathway
els04012  ErbB signaling pathway
els04020  Calcium signaling pathway
els04510  Focal adhesion
els04520  Adherens junction
els04530  Tight junction
Brite
KEGG Orthology (KO) [BR:els00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105030222 (erbb2)
   04012 ErbB signaling pathway
    105030222 (erbb2)
   04020 Calcium signaling pathway
    105030222 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105030222 (erbb2)
   04520 Adherens junction
    105030222 (erbb2)
   04530 Tight junction
    105030222 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:els01001]
    105030222 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:els04147]
    105030222 (erbb2)
   04090 CD molecules [BR:els04090]
    105030222 (erbb2)
Enzymes [BR:els01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     105030222 (erbb2)
Protein kinases [BR:els01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   105030222 (erbb2)
Exosome [BR:els04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   105030222 (erbb2)
CD molecules [BR:els04090]
 Proteins
  105030222 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 105030222
NCBI-ProteinID: XP_028975820
Position
LG05:complement(32893514..32939252)
AA seq 1304 aa
MEAARSFLFGILLVGLSGTLGREVCLGTDMQLALPSSLENQYETLRLLYTGCQVVHGNLE
ITHLQGEPDLSFLQSIVEVQGYVLIAHVSVSIVPLDNLRIIRGSQLYNSSYALAVLDNTL
PRGGRGLRTLRLRNLTEILLGGVMFWGNPQLCFPDPQHMEWRDTLHEKRTDTKYLRLQAR
ALNCPKCSTTCEERGCWGETEQDCQTLTHVGCSSGCLRCKGNESSDCCHSQCAAGCTGPK
DSDCLSCRHFNDSGTCKDNCPPPNIYVPTTFQSIPNPNRKFSFGASCVKTCPYNYLAIEV
ACTMVCPKTDHEVIITQPDGKETQKCEKCEGDCPKVCYGLGMGDLQASSWVSSSNVAQFT
GCKKLYGSLAFLPQSFTRDSNANETGLTISEMEAFKDLEEITGYLYIDAWPANWTNLGVF
ENLKVIRGRMLYMGVFSLAIQSIQIHSLGLRSLQSISGGLVLLHNNSQLCFTQELPWGAL
LHPTQGPHRIVNSNQDPEKCVSEGRTCHPLCIDGCWGPGPTQCVACSKFQRGKECVVECN
IYEGTQREFVDITKRVCGACHPECRPINGSISCHGPGAHQCTECLHHQDVGFCVEKCPSG
LKEDQHTVWKYSNDTGHCLTCDTNCTLSCNQKDDRGCPIHPKSGPGTSIAAAVGGVVLFL
ILLGLLVFYLQRQKRLKRKETMRRILQEHELVEPLTPSGALPNQAQMRILKETELKKLRV
LGSGAFGTVYKGAWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCRL
LGICLTSTVQLVTQLMPYGCLLDYVRENKDHIGSQYLLNWCVQIAKGMSYLEEVRLVHRD
LAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSDV
WSYGVTVWELMTFGAKPYDLIPARDIPELLEGGERLPQPLICTIDVYMIMVKCWMIDPES
RPKFKELVTEFSVMARDPPRYVVIQNDDKMSLSSPVDSQFFRMLLEEEGAEIRDLLDAEE
YLVPQPNFFRPQAENSAPNGASRHHSHRSTDQGLDSEPSMAGGQRSMYSSVSTLGRNQYP
TLPLGASAPSNGPWVPQYPSLLARTTSHHSAGGTSDSVFLDGGPDEAPGSPGRYCKDPTF
PNGGELETDGPLATHHYNPQNHHSLPRRVHLYNHNHALPEYINQEVQDLRPGPGERPSTL
PRKGVAERHRQLPNGLSSGHSVENPEYLVPGMGSNATSPAFDNPYYLDLASKAKAVAGGH
RGSGKNDGGLLSTPRQVNGFVTPTAENPEYLGLADTWSGQREHS
NT seq 3915 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagttttctgtttgggatactgctggtcggactatcgggcacattg
ggcagagaagtatgcctgggcacagacatgcagctggccctgccctccagtctggagaac
caatatgagaccttgcggctgctctacactgggtgccaagtggtccacggcaacctggag
atcacccacctccagggagaaccggacctctcattcctacagagcatcgttgaggtgcag
ggctatgtcttgatcgcccacgtgtccgtgagcattgtgccgctggacaacctgcgcatc
atccgtggcagccagctgtataactccagctacgccctagctgtcctggacaacacactc
cccagaggggggcggggcctcaggacgctccgtctccgcaatctcacagaaatcctgttg
ggtggagtgatgttttggggaaaccctcagctctgttttccggacccccagcacatggag
tggagggacacacttcatgaaaagaggacagacaccaaatacctccgcttgcaggcccgt
gcccttaactgtccaaagtgttccactacctgtgaagaaaggggctgctggggagagaca
gaacaggactgtcagaccttaacccacgtgggctgttcatcggggtgtctgcgctgtaag
ggaaatgagtccagtgactgctgccacagccagtgcgctgccggctgcaccgggccaaaa
gactctgactgtctgtcatgtcgtcacttcaatgatagcggcacgtgtaaggacaactgt
cctcccccaaacatctacgtaccgaccaccttccagtccatacccaaccccaacaggaag
ttcagcttcggagcctcatgtgtcaagacatgtccctataactacttagccattgaggtt
gcctgtaccatggtgtgtcccaaaactgaccatgaagtgattatcacccagcctgatggg
aaggagactcagaagtgtgagaagtgtgaaggggattgtccaaaagtgtgttacggtctg
ggcatgggtgatctccaggcctcctcctgggtcagctcgtccaatgtggcccagttcacc
ggctgtaaaaagctgtatggcagtctggctttccttcctcagagcttcacaagggactca
aatgctaacgagacaggtctgaccatcagtgaaatggaggcgtttaaagatctggaggag
atcactggatatctgtacattgatgcgtggccagcaaactggactaacctgggtgtattt
gagaacctgaaagtgatcagaggaagaatgctctacatgggggtgttctctttggccatc
cagtcaatacagatccattctctgggtctccgttcactccagagcattagtgggggtctg
gttctgctccacaacaactcacagctctgcttcacccaggaacttccctggggggcccta
ctccaccccacccaggggccccaccgaatcgttaactccaaccaggaccctgagaagtgt
gtgtcagagggacgtacctgtcacccgctgtgcattgatggctgctggggtcctgggccc
acccagtgtgtggcctgttccaaattccagcgtgggaaggagtgtgtggtggagtgcaac
atttatgaagggacccagagggagtttgtcgacatcaccaagagagtctgtggcgcctgt
cacccagagtgtagacccatcaatggctctatctcgtgccatggcccgggggcccaccag
tgtacggagtgcctccaccaccaggacgttgggttctgtgtggagaaatgtcccagtggg
ttgaaggaggaccagcacactgtgtggaagtacagcaatgacacaggccactgccttacc
tgtgacaccaactgcacattgtcgtgcaatcagaaagatgacagaggctgccccatccat
cctaaatccgggccggggacgtcgatcgcggcggcggtgggtggggtagtgctcttcctg
atcctgttgggtctgctggtgttctacctccagcgacagaaacggctgaagaggaaggag
accatgaggaggatcctgcaggagcatgagttagtggaacctctgactcccagcggtgcc
ttgcccaaccaggcccagatgcgcatcctcaaggagacagagctaaagaagcttagagtc
ctgggctcaggagcttttggcacagtctacaagggggcgtgggctcccgatggggagaat
gtcaagataccagttgccatcaaggttttgcgcgagaacacctcgcccaaagcaaacaag
gagatccttgatgaggcatacgttatggctggtgtggccagtccttacgtgtgtcgtttg
ctgggaatctgtctgacctccacagttcagctggttacccagctcatgccgtatggatgc
ctgctggactacgtcagagagaacaaggaccacatcggctcccagtatctcctcaactgg
tgtgtgcagattgccaaggggatgagctacctggaggaggttcgtctggtccacagggac
cttgcagcccgtaacgtcctggtaaagaaccctaaccacgtcaagatcactgactttggc
cttgctcgtctgttggatattgacgaaacggagtaccatgcggatggagggaaggtgccc
attaagtggatggcattggaatcgatcctccacagaaagttcacccaccagagcgatgtt
tggagctatggtgtgactgtatgggagctcatgacctttggggccaagccctatgatctg
atccctgcaagagacatcccagaactgctggagggaggcgagaggctcccccagcccctc
atctgcaccattgatgtctacatgatcatggtcaagtgctggatgattgacccagaaagc
aggccaaagttcaaggagctggtgacagagtttagcgtcatggcacgcgacccacctcgc
tacgtggtcatccagaatgatgacaagatgagtttgtctagtccggtggacagtcagttc
ttcaggatgctgctggaagaggagggagcagaaatccgagacctgctggatgctgaggag
tacctggtgccacagcccaacttcttccgaccccaggcagaaaactcagccccgaacggc
gcttcccgacaccactcacacaggagtacagaccagggactagacagcgagccctccatg
gcgggcggccagcgaagcatgtactcctcagttagcaccctggggcggaaccagtacccc
actctgcccctgggggccagtgccccctccaacggtccttgggtcccccagtacccatcc
ctcttggcccgcaccacctcccaccactccgctggtgggacctctgactctgtgttcctg
gacgggggtcctgatgaggccccagggagtccagggcgctactgcaaagacccaaccttc
cccaatggaggagagctggaaaccgacggcccattggcaacgcatcattataacccccag
aatcatcactcgctgccccgcagggttcacctgtataaccacaaccacgctttaccagag
tacatcaaccaggaggttcaggacctccgccctgggcctggcgagcggcccagcaccctg
cctcgcaagggggtggccgaaaggcatcgccagctccccaacggcctgagctcaggacac
agtgttgagaaccctgagtacctggtccccgggatgggctccaacgctacctcccctgct
tttgacaacccctactatctggacctggcgtccaaggctaaagctgtggccggaggccat
cggggttctgggaagaatgatgggggtcttctctcaacccccaggcaggtgaatggcttt
gtgacacccacagctgagaacccggagtaccttggcctcgccgacacctggagtggccag
agggagcactcttga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (66)   
   KEGG ORTHOLOGY (1)   
   RefGene (62)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (92)   

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