KEGG   Escherichia coli W: ECW_m2446Help
Entry
ECW_m2446         CDS       T02002                                 

Gene name
arnA
Definition
(GenBank) fused UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase
  KO
K10011  UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305]
Organism
elw  Escherichia coli W
Pathway
elw00520  Amino sugar and nucleotide sugar metabolism
elw01100  Metabolic pathways
elw01503  Cationic antimicrobial peptide (CAMP) resistance
Module
elw_M00761  Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
Brite
KEGG Orthology (KO) [BR:elw00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    ECW_m2446 (arnA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    ECW_m2446 (arnA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01005 Lipopolysaccharide biosynthesis proteins [BR:elw01005]
    ECW_m2446 (arnA)
Enzymes [BR:elw01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.305  UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
     ECW_m2446 (arnA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.13  UDP-4-amino-4-deoxy-L-arabinose formyltransferase
     ECW_m2446 (arnA)
Lipopolysaccharide biosynthesis proteins [BR:elw01005]
 Unusual sugar
  ECW_m2446 (arnA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Epimerase GDP_Man_Dehyd Formyl_trans_N Formyl_trans_C 3Beta_HSD NAD_binding_10 NAD_binding_4 RmlD_sub_bind
Motif
Other DBs
NCBI-ProteinID: ADT75877
UniProt: E0IY58
Structure
PDB: 

Position
2524109..2526091
Genome map
AA seq 660 aa AA seqDB search
MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPD
NVNHPLWVERIAHLAPEVIFSFYYRHLICDAILQLAPAGAFNLHGSLLPKYRGRAPLNWV
LVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPTI
KHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF
TVWSSRVHPHASKAQPGSVISIAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQ
GSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHP
HFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC
VKYHKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDI
RDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGF
RVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
NT seq 1983 nt NT seq  +upstreamnt  +downstreamnt
atgaaaaccgtcgtttttgcctaccacgatatgggatgcctcggtattgaagccctgctg
gctgccggttacgaaattagcgctatttttactcatactgataatcccggtgaaaaagcc
ttttatggttcggtagctcgtctggcggcggaaagaggcattccggtttatgcgccggat
aacgttaatcatccgctgtgggtggaacgcattgcccacctagcaccagaggtgattttc
tctttttattatcgccatcttatttgcgacgcgattttgcagctcgctcccgcgggtgca
tttaatctgcacggttcgctgttaccaaaatatcgtggtcgcgcgccgctgaactgggtg
ctggtgaacggtgaaacggaaactggcgttacattgcaccgaatggtgaaacgtgccgat
gccggggccattgtggcgcaactgcgcattgccattgcgccagacgatatcgccattacg
ctgcatcataaattgtgccatgccgcgcgccagttgctggaacagacattacccaccatt
aaacacggtaatattctggaaattgcccagcgcgaaaacgaagccacctgttttggtcgc
agaacgccagatgacagtttcctcgaatggcataaaccggcatccgtgctgcacaacatg
gtgcgtgccgtagccgatccgtggccaggtgccttcagctatgttggtaatcagaaattt
accgtctggtcgtcgcgtgttcatcctcatgccagcaaagcacagccggggagcgtgatt
tctattgcaccgctgttgattgcctgtggcgatggcgcgctggaaatcgtcaccggacag
gcgggcgacggcattactatgcagggctcgcaattagcgcagacgctgggcctggtgcaa
ggttcacgcttgaatagccagcctgcctgcaccgcccgacgccgtacccgggtactcatc
ctcggggtaaatggctttattggcaaccatctgacagaacgcctgctgcgcgaagatcat
tatgaagtttacggtctggatattggcagcgatgcgataagccgttttctgaatcatccg
cattttcactttgttgaaggcgatatcagtattcattccgaatggattgagtatcatgtc
aaaaaatgtgatgtcgtcttgccgctggtggcgatagccacgccgattgaatatacccgc
aacccgctgcgcgtatttgaactcgattttgaagagaatctgcgcattatccgctactgc
gtgaagtaccataagcgaatcatcttcccgtcaacttcagaagtttatgggatgtgtagc
gataaatacttcgatgaggaccattctaatttaatcgtcggcccggtgaataaaccacgc
tggatttattcggtatcaaaacaattacttgatcgggtgatctgggcctatggcgaaaaa
gagggtttacagttcaccctcttccgcccgtttaactggatgggaccgcgactggataac
cttaatgcggcacgaatcggcagctcccgcgctattacgcaactcattctcaatctggta
gaaggttcaccgattaagctgattgatggcggaaaacaaaaacgctgctttactgatatt
cgcgatggtatcgaggcgttataccgcattatcgaaaatgcgggaaatcgctgcgacggt
gaaattatcaacattggcaatcctgagaacgaagcgagcattgaggaactgggcgagatg
ctgctggcgagcttcgaaaaacatccgctgcgccatcatttcccaccgtttgcgggcttt
cgcgttgtcgaaagtagcagctactacggcaaaggatatcaggacgtagagcatcgtaaa
ccgagcatccgcaatgcccaccgctgcctggactgggagccgaaaattgatatgcaggaa
accatcgacgaaacgctggatttcttcctgcgcaccgttgatcttacggataaaccatca
tga

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