KEGG   Escherichia coli W: ECW_m4131
Entry
ECW_m4131         CDS       T02002                                 
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase
  KO
K00549  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
Organism
elw  Escherichia coli W
Pathway
elw00270  Cysteine and methionine metabolism
elw00450  Selenocompound metabolism
elw01100  Metabolic pathways
elw01110  Biosynthesis of secondary metabolites
elw01230  Biosynthesis of amino acids
Module
elw_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:elw00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    ECW_m4131 (metE)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    ECW_m4131 (metE)
Enzymes [BR:elw01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.14  5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
     ECW_m4131 (metE)
SSDB
Motif
Pfam: Meth_synt_2 Meth_synt_1
Other DBs
NCBI-ProteinID: ADT77449
UniProt: E0J3W6
Position
4237585..4239846
AA seq 753 aa
MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLP
VGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFN
TNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTYLWLGKVKGEQFDR
LSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLL
TTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRAD
LTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLR
DALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRAR
FKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYA
QSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDE
PALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDAD
VITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERL
WVNPDCGLKTRGWPETRAALANMVQAAQNLRLG
NT seq 2262 nt   +upstreamnt  +downstreamnt
atgacaattcttaatcacaccctcggtttccctcgcgttggcctgcgtcgcgagctgaaa
aaagcgcaagaaagttattgggcggggaactccacgcgtgaagaactgctgacagtaggg
cgtgaactgcgtgctcgtcactgggatcaacaaaagcaagcgggtatcgacctgctgccg
gtgggcgattttgcctggtacgatcatgttctgaccaccagtctgctgctgggtaatgtt
ccgccacgtcatcagaacaaagacggttcggtagatatcgacaccctgttccgtattggt
cgtggacgtgcgccgactggcgaacctgcggcggcagcggaaatgaccaaatggtttaac
accaactatcactacatggtgccggaattcgttaaaggccaacagttcaaactgacctgg
acgcagctgctggaggaagtggacgaggcgctggcgctgggccacaacgttaagcctgtg
ctgctggggccggttacttacctgtggctggggaaagtgaaaggtgaacagtttgaccgc
cttagcctgctgaacgacattctgccggtttatcagcaagtgctggcagaactggcgaaa
cgcggcatcgagtgggtacagattgatgaacccgcgctggtactggaactaccacaggcg
tggctggacgcatacaaacccgcttacgacgcgctccagggacaggtgaaactgctgctg
accacctattttgaaggcgtaacgccaaatctcgacacgattactgcgctgcctgttcag
ggtctgcatgttgacctcgtacatggtaaagatgacgttgctgaactgcacaagcgcctg
ccttctgactggttgctgtctgcgggtctgatcaatggtcgtaacgtctggcgcgccgat
cttaccgagaaatatgcgcaaattaaggacattgtcggcaaacgtgatttgtgggtggca
tcttcctgctcgttgctgcacagccccatcgacctgagcgtggaaacgcgtcttgatgca
gaagtgaaaagctggtttgccttcgccctacaaaaatgccatgaactggcactgctgcgc
gatgcgctgaacagtggtgacacggcagctctggcagagtggagcgccccgattcaggca
cgtcgtcactctacccgcgtacataatccggcggtagaaaagcgtctggcggcgatcacc
gcccaggacagccagcgtgcgaatgtctatgaagtgcgtgccgaagcccagcgtgcgcgt
tttaaactgccagcgtggccgaccaccacgattggttctttcccgcaaaccacggaaatt
cgtaccctgcgtctggatttcaaaaagggcaatctcgacgccaataactaccgcacgggc
attgcggaacatatcaggcaggccattgttgaacaggaacgtttgggactggatgtgctg
gtacatggcgaggccgagcgtaatgacatggtggaatactttggcgagcacctcgacggg
tttgtctttacgcaaaacggttgggtacagagctacggttcccgctgcgtgaagccaccg
attgttattggtgacgttagtcgcccggcaccgattaccgtggagtgggcgaagtatgcg
caatcgctgaccgacaaaccggtgaaagggatgctgacggggccggtgaccatactctgc
tggtcgttcccgcgtgaagatgtcagccgtgaaaccatcgccaaacagattgcgctggcg
ctgcgtgatgaggtggccgatctggaagcggcagggattggtatcatccagattgacgaa
ccggcgctgcgcgaaggtttaccactgcgtcgtagcgactgggacgcctatctccagtgg
ggcgtagaggccttccgtatcaacgccgccgtggcgaaagatgacacacaaatccacact
cacatgtgttattgcgagttcaacgacatcatggattccattgcggcgctggatgcagac
gtcatcaccatcgaaacctcgcgttccgacatggagttgctggagtcgtttgaagagttt
gattatccgaatgaaatcggtccaggcgtctatgacattcactcgccaaacgtaccgagc
gtggaatggattgaagccctgctgaagaaagcggcaaaacgcattccggcagagcgcctg
tgggtcaacccagactgtggcctgaaaacgcgcggctggccagaaacccgcgcggcactg
gcgaacatggtgcaggcggcgcagaatttgcgtctggggtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (24)   

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