KEGG   Escherichia coli NA114 (UPEC): ECNA114_0069
Entry
ECNA114_0069      CDS       T01998                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ena  Escherichia coli NA114 (UPEC)
Pathway
ena00290  Valine, leucine and isoleucine biosynthesis
ena00620  Pyruvate metabolism
ena01100  Metabolic pathways
ena01110  Biosynthesis of secondary metabolites
ena01210  2-Oxocarboxylic acid metabolism
ena01230  Biosynthesis of amino acids
Module
ena_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ena00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    ECNA114_0069 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ECNA114_0069 (leuA)
Enzymes [BR:ena01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     ECNA114_0069 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AEG34891
Position
complement(74491..76062)
AA seq 523 aa
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF
LKLADKKGQVFDYDLEALAFIDKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA
EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag
gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt
gacgtgatggaagtcggtttccccgtctcttcgccgggtgattttgaatcagtgcagacc
atcgctcgccaggttaaaaacagccgtgtatgcgcgttagctcgctgcgtggagaaagat
atcgacgtggcagccgaatccctgaaagtcgccgaagccttccgtattcatacctttatt
gccacttcgccaatgcacatcgccaccaagctgcgcagcacgctggacgaagtgatcgaa
cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc
gaagatgccggacgcaccccaattgccgatctggcgcgagtggtcgaagcggcgattaat
gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccatttgagttc
gccggaatcatcagcggcctgtatgaacgcgtacccaacatcgacaaagccattatttcc
gtacatacccacgacgatttgggcctggcggtcggcaactcactggcggcggtacatgcc
ggagcacggcaggtagaaggcgcaatgaacgggatcggcgagcgtgccggtaactgttcc
cttgaagaagtcatcatggcgatcaaagttcgtaaggatattctcaacgtccacaccgcc
atcaatcaccaggagatatggcgcaccagccagttagttagccagatttgtaatatgccg
atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtatccac
caggatggtgtactgaaaaaccgcgaaaactacgaaatcatgacaccagaatctattggt
ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc
atggatgagatgggatataaagaaagtgaatataatttagacaacctgtacgacgctttc
ctgaagctggcggacaaaaaaggccaggtgtttgattacgatctggaggcgctggccttc
atcgataagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtca
ggttctaacgatattgccactgccgccgtcaaactggcctgtggcgaagaagttaaagca
gaagccgctaacggcaacggcccggttgatgccgtctaccaggcgataaaccgcatcact
gactataacgtcgaactggtgaaatacagcctgaccgccaaaggtcacggtaaagatgcg
ctgggtcaggtggatattgtcgccaactacaacggtcgccgcttccacggcgtcggcctg
gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtactgaacaatatctgg
cgtgccgcagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag
gaaaccgtgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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