KEGG   Enterobacter cloacae subsp. cloacae ATCC 13047: ECL_04744Help
Entry
ECL_04744         CDS       T01231                                 

Definition
(RefSeq) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
enc  Enterobacter cloacae subsp. cloacae ATCC 13047
Pathway
enc00860  Porphyrin and chlorophyll metabolism
enc01100  Metabolic pathways
enc01110  Biosynthesis of secondary metabolites
enc01120  Microbial metabolism in diverse environments
Module
enc_M00846  Siroheme biosynthesis, glutamate => siroheme
Brite
KEGG Orthology (KO) [BR:enc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    ECL_04744
Enzymes [BR:enc01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     ECL_04744
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     ECL_04744
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     ECL_04744
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Radical_SAM
Motif
Other DBs
NCBI-GeneID: 9127214
NCBI-ProteinID: YP_003615220
UniProt: A0A0H3CQM3
Position
4853893..4855266
Genome map
AA seq 457 aa AA seqDB search
MDHLPIFCQLRHRDCLLVGGGDVAERKARLLLEAGARLTVNALAFAPQFEAWAKEGMLTL
NQGEFNESLLDTCWLTIAATDDDEVNQRVSDACEARRIFCNVVDAPKEASFIMPSIIDRS
PLMIAVSSGGRSPVLARLLREKLEALLPQHLGQIAHYAGQLRSRVKQTFATVGERRRFWE
KFFVNDRLAQSLANQDVKAVEETTEQLLSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQ
QADTVVYDRLVSDEIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHL
KTGSELDWHNLAAEKQTLVFYMGLNQAATIQAKLLEHGMEADMPVALVENGTSIKQRVVN
GVLTQLGELAQQVESPALIIVGRVVELRDKLNWFSNH
NT seq 1374 nt NT seq  +upstreamnt  +downstreamnt
gtggaccacctgccgattttctgtcaattacgccatcgcgactgcctgcttgtgggtggc
ggcgatgtggctgaacgcaaagcccgcttgctgttagaggcaggtgcccgtcttacggtt
aacgccctcgccttcgcaccacagtttgaagcctgggcgaaggaagggatgctcacgctg
aatcagggggagtttaacgagtccctgctggatacctgctggctgactattgccgcgacg
gatgacgatgaagtgaatcagcgcgtcagcgatgcctgcgaagcgcgccgtatattctgc
aacgtggtggatgcgccgaaagaagccagctttatcatgccgtcgataatcgaccgttca
ccactgatgattgcggtgtcgtcaggtggccgctcgccggttctcgcccgcctgctgcgg
gaaaaactggaagcactgctgccgcaacatcttggacaaattgcccactatgcagggcaa
ctgcgttcacgagtgaagcaaaccttcgcgaccgtgggcgagcgccgtcgcttctgggaa
aaattcttcgtcaatgaccggctggcccagtcgctggccaatcaggacgtgaaggcggtt
gaagagacgaccgagcagttactctctgaaccgctggatcatcgtggcgaggtggttctg
gtgggtgcaggccccggcgatgcgggattactgacgctgaaaggactccagcagatccag
caggccgataccgttgtgtatgaccgtctggtctccgatgagatcatgaatctggtacgt
cgcgatgcggaccgggtgtttgtgggtaaacgtgcgggttatcactgcgtgccgcaggaa
gagattaaccagatcctgctgcgggaagcgcaaaaaggaaaacgtgtggtgcgcctgaag
ggcggggatccgtttatctttggtcgcggcggcgaggaactggaaaccctctgcaacgca
ggtattccgttctctgtggtgcctggcattacggcggcatccggctgttcggcatactcc
ggtattccattgacccatcgtgattacgcgcagagcgtgcgtctggtgacggggcacctg
aaaaccggcagcgaactggactggcacaacctggccgccgaaaagcagacgctggtcttc
tatatggggctgaatcaggccgctacgatccaggcgaaattactggaacacggcatggaa
gcggatatgcccgtcgcgctggtggaaaacggcacctccattaagcagcgcgtggtaaat
ggcgtgctgacacagctgggtgagctggcgcagcaggttgaaagcccggcgctgattatt
gtcggccgcgtggtcgagctgcgcgataaactcaactggttctcaaatcactag

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