KEGG   Enterobacter sp. 638: Ent638_0222
Entry
Ent638_0222       CDS       T00507                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ent  Enterobacter sp. 638
Pathway
ent00270  Cysteine and methionine metabolism
ent00450  Selenocompound metabolism
ent00670  One carbon pool by folate
ent01100  Metabolic pathways
ent01110  Biosynthesis of secondary metabolites
ent01230  Biosynthesis of amino acids
Module
ent_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ent00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Ent638_0222
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Ent638_0222
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Ent638_0222
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    Ent638_0222
Enzymes [BR:ent01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Ent638_0222
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ABP58912
UniProt: A0A9J9GDX3
Position
263243..266926
AA seq 1227 aa
MSSKIEQLRAQLNERILVLDGGMGTMIQSYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PDVIAAIHHAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFTAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNVTFDQLVAAYRESTKALVEGGSDLIMI
ETVFDTLNAKAAIFAVKEEMEALGVDLPIMVSGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVQELSRIADCYVTAHPNAGLPNAFGEYDLDAVTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSHAVAGLPPRKLPDLPVACRLAGLEPLTISKESLFVNVG
ERTNVTGSAKFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEPFIHHAKKVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELREGVEDVILNRRDDATERMLDLAEKYRGSKADESVNIQQAEWRAWDVK
KRLEYSLVKGITEFIELDTEEARQQAARPIEVIEGPLMDGMNVVGDLFSEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKEKSSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILKTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTQRDDFVARTRKEYDTVRIQHARKKPR
TPPVTLAAARENDLAFDWSSYTPPVAHRLGVQDVTASIETLRNYIDWTPFFMTWSLAGKY
PRILEDDVVGEEAQRLFKDANDMLDQLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
NVLAVSRHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKAISDRLAEAFAEYLHERVRKVHWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVETHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaaatagagcaactgcgtgcgcagttaaacgaacgaattctggtgctggac
ggcggcatgggcaccatgatccaaagctaccgtctgagcgaagacgatttccgcggcgaa
cgtttcgccgactggccctgcgacctgaaaggcaacaatgacctgctggtgctcagtaaa
cctgacgtcattgcggcgattcatcacgcctattttgaggcgggtgcggacatagtcgaa
accaacacgtttaactcgaccaccatcgccatggccgattaccagatggaatccctgtcg
gcggaaatcaacttcaccgcggcaaagctggcgcgcgcctgcgctgacgaatggaccgcg
cgaacgccggaaaaaccccgctatgtggccggcgttctggggccgactaaccgtaccgcg
tcaatttcaccagacgttaacgaccctgctttccgtaacgtcaccttcgatcaactggtg
gccgcgtatcgtgaatcgaccaaagcgctggtggaaggcggttccgatctgattatgatc
gaaacggtcttcgacacgctcaatgctaaagccgccatcttcgccgtaaaagaagagatg
gaagcgctgggcgttgatttgccgatcatggtgtctggcaccattaccgacgcctccggg
cgtacgctctccgggcagacaaccgaagcgttttacaactccctgcgccacgcggatgcg
ctgaccttcggcctgaactgtgcgttggggcctgacgaactgcgtcagtacgtccaggaa
ctttcacgtatcgccgattgctacgtcaccgcgcaccccaatgcgggcctgccaaacgct
tttggggagtacgatcttgatgcggtgaccatggcggcgcaaattcgtgaatgggccgag
tccggcttcctgaatattgttggtggctgctgcggcaccacgccagaacatatcgccgcg
atgagtcacgccgtagcgggtttgccgccgcgcaagctgccggatctgccggtggcctgt
cgtctggcgggtcttgaaccgctgaccattagcaaagagagcctgtttgtgaacgtcggt
gaacgaactaacgtcaccggctctgccaaattcaaacggctgatcaaagaagagaaatac
aacgaagcgctggacgttgcgcgtcaacaggtcgaaagcggcgcgcagatcatcgacatc
aacatggatgaagggatgctcgacgccgaagcggcgatggtgcgtttcctgaatttgatt
gccggtgagccagatatcgcccgcgtgccgatcatgatcgactcctcaaaatgggaggtc
attgaaaaagggctgaagtgcatccagggtaaaggcatcgttaactccatctcgatgaaa
gagggcgttgagccgtttatccaccacgctaaaaaggtgcgtcgttacggcgcggcagtc
gtggtcatggcctttgatgaagtcggtcaggcggatacgcgcgagcgcaaaattgagatt
tgccgccgcgcctacaagatcttgaccgaagaggtcggcttcccgccggaagacattatt
ttcgacccgaatattttcgccgtcgcgaccggtatcgaagagcacaacaactatgcgcag
gattttattggcgcgtgtgaagacatcaaacgcgagctgccgcatgcgctgatctccggc
ggcgtttccaacgtgtcgttctcgttccgtggcaacgacccggtgcgtgaggcgatccac
gccgtattcctctactacgcgattcgcaacgggatggacatgggcatcgtcaacgccgga
cagctggcgatttacgatgacctgcctgccgagctgcgcgagggtgtggaagatgtcatt
ttaaaccgtcgcgatgacgccaccgaacgcatgctggatctggcagaaaaatatcgcggc
agtaaagccgatgaaagcgtcaatattcagcaggcggaatggcgcgcctgggatgtgaaa
aaacgtctggaatattcgctggtcaaagggatcaccgagtttatcgagctggacaccgaa
gaagcgcgccagcaggctgcacgccctatcgaagtgattgaaggcccgctgatggacggc
atgaacgtggtgggtgatctgttcagcgagggaaaaatgttcctgccgcaggtggtgaaa
tctgcgcgtgtgatgaagcaagccgtggcctatctcgagccttacattgaggccagcaaa
gaaaaaagttccagcaacggcaagatggtgatcgccaccgtgaagggcgatgtgcatgac
atcggcaaaaatatcgtcggcgtggtgctgcagtgtaataactacgaaatcatcgattta
ggcgtgatggttccggcggataaaatcctcaaaactgcgcgggaagtgaatgccgatctg
attggcttgtccgggttgatcaccccgtcgctcgacgaaatggttaacgtggcaaaagag
atggaacgccagggctttaccattccgctgctgattggcggggcgaccacctcaaaagcg
catacggcggtcaaaattgagcagaactacagcggtccgacggtctacgtgcagaacgct
tcgcgcaccgttggcgtggtgtctgcactgctgtccgacacgcaacgcgatgattttgtg
gcgagaacgcgcaaagagtacgacaccgtgcgtatccagcatgcgcgtaaaaagccgcgt
acaccgccggtgacgcttgccgccgcgcgcgaaaacgatctggcattcgactggtcaagc
tacacaccgcccgtggcgcaccgtttgggcgtgcaggacgtcaccgccagcatcgaaacg
ctgcgtaattacatcgactggacgccgttcttcatgacctggtcgctggccgggaaatac
ccgcgcatcctcgaggatgatgtggtgggcgaagaagcccagcgcttgttcaaagatgcc
aacgatatgctcgaccagctaagtgcagaaaaaacgctgaatccgcgcggtgtggttggc
ctgttcccggcgaatcgcgtgggcgatgacatcgaaatttatcgtgatgaaacccgcacc
aacgtgctggcggtcagccgtcatctgcgccagcaaactgaaaaagtcgggtttgcgaac
tactgcctggccgattttgtcgcgcctaaactgagcggcaaagcggactacattggcgcg
tttgccgtcaccgggggccttgaagaagacgccctcgcagatgcgtttgaagcacagcac
gatgattacaacaaaatcatggttaaagcgatttctgaccgactggccgaagccttcgcg
gaatatctgcatgagcgcgtgcgcaaagtgcactggggttatgctccgaacgaaaacctc
agcaatgaggagctgattcgcgagaactaccagggtattcgcccggcgcctggctatccg
gcgtgccctgaacacaccgagaaagggacgatctggcaacttctggatgtcgaaacccat
accggcatgaagctgacggaatccttcgctatgtggcccggcgcgtccgtttcgggctgg
tatttcagtcatcctgacagcaaatattacgcagtcgcacagattcaacgcgatcaagtg
gaagactacgccttacgtaaagggatgagcgtctcagaagtggagcgctggttagcgcca
aatctgggctacgacgcggattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (43)   

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