KEGG   ENZYME: 1.1.1.107Help
Entry
EC 1.1.1.107                Enzyme                                 

Name
pyridoxal 4-dehydrogenase;
pyridoxal dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
pyridoxal:NAD+ 4-oxidoreductase
Reaction(IUBMB)
pyridoxal + NAD+ = 4-pyridoxolactone + NADH + H+ [RN:R01707]
Reaction(KEGG)
Substrate
pyridoxal [CPD:C00250];
NAD+ [CPD:C00003]
Product
4-pyridoxolactone [CPD:C00971];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme acts on the hemiacetal form of the substrate.
History
EC 1.1.1.107 created 1972
Pathway
ec00750  Vitamin B6 metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K18609  pyridoxal 4-dehydrogenase
Genes
MLO: mlr6807
MCI: Mesci_2032
MAM: Mesau_02096
Taxonomy
Reference
1  [PMID:4306030]
  Authors
Burg RW, Snell EE.
  Title
The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase.
  Journal
J Biol Chem 244:2585-9 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.107
IUBMB Enzyme Nomenclature: 1.1.1.107
ExPASy - ENZYME nomenclature database: 1.1.1.107
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.107
BRENDA, the Enzyme Database: 1.1.1.107
CAS: 37250-39-8

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