KEGG   ENZYME: 1.1.1.120Help
Entry
EC 1.1.1.120                Enzyme                                 

Name
galactose 1-dehydrogenase (NADP+);
D-galactose dehydrogenase (NADP+);
galactose 1-dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-galactose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
D-galactose + NADP+ = D-galactono-1,5-lactone + NADPH + H+ [RN:R01096]
Reaction(KEGG)
R01096;
(other) R01097
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Substrate
D-galactose [CPD:C00124];
NADP+ [CPD:C00006]
Product
D-galactono-1,5-lactone [CPD:C02669];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on L-arabinose, 6-deoxy- and 2-deoxy-D-galactose.
History
EC 1.1.1.120 created 1972
Pathway
ec00052  Galactose metabolism
ec01100  Metabolic pathways
Orthology
K22215  galactose dehydrogenase
Genes
MTHD: A3224_13280
HAF: C8233_02095
CMAI: BFX80_08845
MARS: A8C75_00495
TSN: W908_05220
MLO: mlr4741
MLN: A9174_03560
MCI: Mesci_0734
MOP: Mesop_0751
MAM: Mesau_00714
MES: Meso_3587
AMIH: CO731_00808(kduD_1)
SME: SMc00880
SMX: SM11_chr0479(fabG2)
SMEL: SM2011_c00880(fabG2)
SMER: DU99_04260
SMD: Smed_0438
SFH: SFHH103_00504(fabg1)
SFD: USDA257_c05370(bacC1)
SAME: SAMCFNEI73_Ch0860(bacC)
EAD: OV14_1758
ATU: Atu0705(fabG)
ARA: Arad_1105(fabG1)
ATF: Ach5_06290(fabG)
AGR: AGROH133_04267(fabG)
RET: RHE_CH00855(fabG1)
REC: RHECIAT_CH0000944(fabG1)
RLE: RL0917
RLG: Rleg_0546
RHL: LPU83_0965(fabG1)
RHT: NT26_3705(fabG)
SHZ: shn_03770
RSP: RSP_1369
JAN: Jann_3834
RDE: RD1_2866
DSH: Dshi_1243
PSF: PSE_2806
PGD: Gal_02755
MALG: MALG_02110
SPSE: SULPSESMR1_02141(xylB)
RMM: ROSMUCSMR3_00498(xylB)
LVS: LOKVESSMR4R_02335(xylB)
 » show all
Taxonomy
Reference
1  [PMID:5845847]
  Authors
Cline AL, Hu AS.
  Title
The isolation of three sugar dehydrogenases from a psuedomonad.
  Journal
J Biol Chem 240:4488-92 (1965)
Reference
2  [PMID:5845848]
  Authors
Cline AL, Hu AS.
  Title
Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad.
  Journal
J Biol Chem 240:4493-7 (1965)
Reference
3  [PMID:5845849]
  Authors
Cline AL, Hu AS.
  Title
Some physical properties of three sugar dehydrogenases from a pseudomonad.
  Journal
J Biol Chem 240:4498-502 (1965)
Reference
4  [PMID:4387016]
  Authors
Schiwara HW, Domagk GF.
  Title
[Degradation of deoxysurgars by bacterial enzymes. V. Purification and characterization of an NADP-dependent abequose dehydrogenase from Pseudomonas putida]
  Journal
Hoppe Seylers Z Physiol Chem 349:1321-9 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.120
IUBMB Enzyme Nomenclature: 1.1.1.120
ExPASy - ENZYME nomenclature database: 1.1.1.120
BRENDA, the Enzyme Database: 1.1.1.120
CAS: 37250-51-4

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