KEGG   ENZYME: 1.1.1.122Help
Entry
EC 1.1.1.122                Enzyme                                 

Name
D-threo-aldose 1-dehydrogenase;
L-fucose dehydrogenase;
(2S,3R)-aldose dehydrogenase;
dehydrogenase, L-fucose;
L-fucose (D-arabinose) dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-threo-aldose:NAD+ 1-oxidoreductase
Reaction(IUBMB)
a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH + H+ [RN:R07148]
Reaction(KEGG)
R07148 > R08926;
(other) R07675
Show
Substrate
D-threo-aldose [CPD:C02143];
NAD+ [CPD:C00003]
Product
D-threo-aldono-1,5-lactone [CPD:C16581];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on L-fucose, D-arabinose and L-xylose; the animal enzyme was also shown to act on L-arabinose, and the enzyme from Pseudomonas caryophylli on L-glucose.
History
EC 1.1.1.122 created 1972
Pathway
ec00051  Fructose and mannose metabolism
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Orthology
K00064  D-threo-aldose 1-dehydrogenase
Genes
OLU: OSTLU_31498
OTA: OT_ostta05g00340
BPG: Bathy03g00590
MIS: MICPUN_59526
MPP: MICPUCDRAFT_65131
SMIN: v1.2.030167.t1(symbB.v1.2.030167.t1)
AAF: AURANDRAFT_62320 AURANDRAFT_68834
EHX: EMIHUDRAFT_462242
ECOO: ECRM13514_5689
ECOH: ECRM13516_5429
EAE: EAE_12040
EAR: CCG31537
SERF: L085_03455
ECA: ECA0250
PATR: EV46_01375
PATO: GZ59_02810
DDQ: DDI_0877
XCA: xcc-b100_0158(fdh)
XCI: XCAW_00111(tas) XCAW_00552(tas)
XOO: XOO4539(Tas)
XOM: XOO4276(XOO4276)
XOP: PXO_03262
XAL: XALC_0444
XPH: XppCFBP6546_11135(XppCFBP6546P_11135) XppCFBP6546_13450(XppCFBP6546P_13450)
SML: Smlt1679
VNI: VIBNI_B0418(pld)
PFC: PflA506_2323(pld1)
PFB: VO64_0794
PMAN: OU5_6061
PSA: PST_2004
PSTT: CH92_11250
PSEM: TO66_18440
PANR: A7J50_2453
PSIL: PMA3_10780
ABY: ABAYE1312
ABN: AB57_2577
PART: PARC_b0008
CJA: CJA_1135
LHA: LHA_3083
LLG: 44548918_01690(pld1)
GAI: IMCC3135_03275(pld1_1) IMCC3135_04530(fdh) IMCC3135_09520(pld1_2) IMCC3135_12580(pld1_3) IMCC3135_19460(pld1_4)
CSA: Csal_0369
SALN: SALB1_2489
REH: H16_A1691(h16_A1691)
CNC: CNE_2c21340(pld2)
BPSE: BDL_4018(pld1)
BPSM: BBQ_5407(pld1)
BPSU: BBN_4189(pld1)
BPSD: BBX_5856(pld1)
BPK: BBK_3703(pld1)
BPSO: X996_3970(pld1)
BUT: X994_3829(pld1)
BCJ: BCAS0159
BCEW: DM40_5652
BAM: Bamb_1225
BMUL: NP80_5200
BDL: AK34_5058(pld1)
BLAT: WK25_18475
BTEI: WS51_30150
BSTG: WT74_27295
BGU: KS03_4084(pld1)
BGO: BM43_3348 BM43_4447(pld1)
BXB: DR64_4344(pld1) DR64_5290(pld1)
BFN: OI25_5368(pld1)
PPUL: RO07_16975
POL: Bpro_2212
AAA: Acav_1659
VEI: Veis_0846
HYB: Q5W_24350
JAG: GJA_3273
CARE: LT85_3072
CPRA: CPter91_0381(pld1)
MXA: MXAN_0697
MES: Meso_1609
SMD: Smed_3226
SFD: USDA257_c58770(pld)
RLE: RL0520
RLG: Rleg_0159
SHZ: shn_02850
OAN: Oant_0357
OAH: DR92_2583(pld1)
OCH: CES85_0301(pld1)
BJA: blr1124
BRS: S23_66950
XAU: Xaut_1060
AZC: AZC_2780
MAQU: Maq22A_c15790(tas)
MMED: Mame_04204(pld1_1) Mame_04375(pld1_2) Mame_04711(pld1_3)
HDI: HDIA_0473(pld1_1) HDIA_2064(pld1_2) HDIA_3111(pld1_3)
CAK: Caul_1547
RSP: RSP_0351
JAN: Jann_2111
PSF: PSE_5072
OAT: OAN307_c01080(pld)
OAR: OA238_c17010(pld1) OA238_c17920(pld2) OA238_c24200(pld3)
OTM: OSB_06460(pld1)
HNE: HNE_2134
HBA: Hbal_2682
NAR: Saro_2433
STAX: MC45_18180
SPHI: TS85_17835
SINB: SIDU_14910
GOH: B932_2844
ASZ: ASN_3382 ASN_866(fdh)
BCE: BC3410
BCZ: BCE33L3116(fdh)
BCQ: BCQ_3213(fdh)
BNC: BCN_3231
BTK: BT9727_3188(fdh)
BTM: MC28_4111
BTG: BTB_c34760(pld)
BTI: BTG_02535
BTW: BF38_4571
BCL: ABC1415
BMQ: BMQ_3843
BMD: BMD_3834
BMH: BMWSH_1380(fdh)
BMEG: BG04_758
BEO: BEH_26555
OIH: OB0307
JEO: JMA_10050
TPR: Tpau_0762
SCO: SCO0349(SCF41.08) SCO7162(SC9A4.24c)
SGB: WQO_33030
SFA: Sfla_0438
SVE: SVEN_0070
SALS: SLNWT_0634
STRP: F750_6560
SFI: SFUL_52
SALU: DC74_2136
SALL: SAZ_11255
SLD: T261_6573
SAMB: SAM23877_7134(fdh)
SPRI: SPRI_0778
SRW: TUE45_00156(fdh) TUE45_06264(pld1)
SLE: sle_17780(sle_17780)
SLAU: SLA_3544
MTS: MTES_2573
ARR: ARUE_c39320(pld)
ARM: ART_3287
AAU: AAur_3798
BCV: Bcav_4072
LMOI: VV02_06950
CFL: Cfla_3459
CFI: Celf_0193
MPH: MLP_07540
KFL: Kfla_5175
NDA: Ndas_1187
SRO: Sros_8210
ACE: Acel_1596
KRA: Krad_4195
SEN: SACE_3934
AMI: Amir_0396
SESP: BN6_04340(pld1)
KAL: KALB_480
ACTI: UA75_11960
ACAD: UA74_11875
AHG: AHOG_11200(fdh)
ACTN: L083_5672
AFS: AFR_29090
RCA: Rcas_4422
TTR: Tter_0272
RBA: RB5820(fucO)
ABAS: ACPOL_2911
MBAS: ALGA_0097
SMIZ: 4412673_01909(fdh)
GFL: GRFL_2858
ZPR: ZPR_1994
RAI: RA0C_1703
RAR: RIA_0787
RAG: B739_0451
RAE: G148_0129
RAT: M949_0898
CTAK: 4412677_00569(pld1)
 » show all
Taxonomy
Reference
1  [PMID:40609]
  Authors
Sasajima KI, Sinskey AJ.
  Title
Oxidation of L-glucose by a Pseudomonad.
  Journal
Biochim Biophys Acta 571:120-6 (1979)
DOI:10.1016/0005-2744(79)90232-8
Reference
2  [PMID:4309152]
  Authors
Schachter H, Sarney J, McGuire EJ, Roseman S.
  Title
Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver.
  Journal
J Biol Chem 244:4785-92 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.122
IUBMB Enzyme Nomenclature: 1.1.1.122
ExPASy - ENZYME nomenclature database: 1.1.1.122
BRENDA, the Enzyme Database: 1.1.1.122
CAS: 9082-70-6

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