KEGG   ENZYME: 1.1.1.163Help
Entry
EC 1.1.1.163                Enzyme                                 

Name
cyclopentanol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cyclopentanol:NAD+ oxidoreductase
Reaction(IUBMB)
cyclopentanol + NAD+ = cyclopentanone + NADH + H+ [RN:R02553]
Reaction(KEGG)
R02553;
(other) R02229
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Substrate
cyclopentanol [CPD:C02020];
NAD+ [CPD:C00003]
Product
cyclopentanone [CPD:C00557];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
4-Methylcyclohexanol and cyclohexanol can also act as substrates.
History
EC 1.1.1.163 created 1976
Pathway
ec00930  Caprolactam degradation
Orthology
K17754  cyclopentanol dehydrogenase
Genes
PPJ: RK21_02868
POL: Bpro_5564
AJS: Ajs_2100
ADK: Alide2_4312
PLA: Plav_1760
PMO: Pmob_0729
Taxonomy
Reference
1  [PMID:4349113]
  Authors
Griffin M, Trudgill PW.
  Title
The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.
  Journal
Biochem J 129:595-603 (1972)
Reference
2  [PMID:12406764]
  Authors
Iwaki H, Hasegawa Y, Wang S, Kayser MM, Lau PC.
  Title
Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase.
  Journal
Appl Environ Microbiol 68:5671-84 (2002)
DOI:10.1128/AEM.68.11.5671-5684.2002
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.163
IUBMB Enzyme Nomenclature: 1.1.1.163
ExPASy - ENZYME nomenclature database: 1.1.1.163
BRENDA, the Enzyme Database: 1.1.1.163
CAS: 37364-12-8

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