KEGG   ENZYME: 1.1.1.179Help
Entry
EC 1.1.1.179                Enzyme                                 

Name
D-xylose 1-dehydrogenase (NADP+);
D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase;
D-xylose-NADP dehydrogenase;
D-xylose:NADP+ oxidoreductase;
D-xylose 1-dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-xylose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
D-xylose + NADP+ = D-xylono-1,5-lactone + NADPH + H+ [RN:R01430]
Reaction(KEGG)
Substrate
D-xylose [CPD:C00181];
NADP+ [CPD:C00006]
Product
D-xylono-1,5-lactone [CPD:C02266];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly, on L-arabinose and D-ribose.
History
EC 1.1.1.179 created 1982
Pathway
ec00040  Pentose and glucuronate interconversions
Orthology
K00078  dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP)
K14273  D-xylose 1-dehydrogenase (NADP+)
Genes
HSA: 27294(DHDH)
PTR: 456194(DHDH)
PPS: 100991467(DHDH)
GGO: 101152398(DHDH)
PON: 100174691(DHDH)
NLE: 100591778(DHDH)
MCC: 718930(DHDH)
MCF: 102133381(DHDH)
CSAB: 103235003(DHDH)
RRO: 104666542(DHDH)
RBB: 108523635(DHDH)
CJC: 100390604(DHDH)
SBQ: 101049549(DHDH)
MMU: 71755(Dhdh)
RNO: 691002(Dhdh)
CGE: 100753544(Dhdh)
NGI: 103743638(Dhdh)
HGL: 101713222(Dhdh)
CCAN: 109682683(Dhdh)
OCU: 100008610(DHDH)
TUP: 102470508(DHDH)
CFA: 403786(DHDH)
AML: 100477136(DHDH)
UMR: 103657108(DHDH)
ORO: 101371357(DHDH)
FCA: 101101272(DHDH)
PTG: 102948867(DHDH)
AJU: 106988698(DHDH)
BTA: 617564(DHDH)
BOM: 102280401(DHDH)
BIU: 109571974 109572213(DHDH)
PHD: 102323268(DHDH)
CHX: 102188075(DHDH)
OAS: 101103175(DHDH)
SSC: 397337(DHDH)
CFR: 102512639(DHDH)
CDK: 105102891(DHDH)
BACU: 103008204(DHDH)
ECB: 100051521(DHDH)
EPZ: 103553311(DHDH)
EAI: 106838267(DHDH)
MYB: 102262437(DHDH)
MYD: 102770117(DHDH)
HAI: 109391066(DHDH)
RSS: 109452566(DHDH)
PALE: 102885391(DHDH)
LAV: 100660549(DHDH)
TMU: 101355202
MDO: 100030403(DHDH)
SHR: 111720213(DHDH)
GGA: 777348(DHDH)
MGP: 104916162(DHDH)
CJO: 107325868(DHDH)
PHI: 102104923(DHDH)
PMAJ: 107199051(DHDH)
ASN: 102376323(DHDH)
AMJ: 102574630(DHDH)
PSS: 102447655(DHDH)
CMY: 102931206
XLA: 108697264 444539(dhdh)
XTR: 100145807(dhdh) 448579(dhdh)
DRE: 406433(dhdhl) 449558(zgc:101723)
SGH: 107553352 107595342(dhdh)
IPU: 100528487(dhdh)
MZE: 101466663
NFU: 107381267(dhdh) 107381268
SFM: 108930140
LCM: 102353287(DHDH)
CMK: 103189533(dhdh)
CIN: 100186038
DME: Dmel_CG13280(CG13280) Dmel_CG3597(CG3597) Dmel_CG3609(CG3609)
DSI: Dsimw501_GD11964(Dsim_GD11964) Dsimw501_GD22839(Dsim_GD22839) Dsimw501_GD22840(Dsim_GD22840)
MDE: 101900891
AAG: 5572674
AME: 412231
BIM: 100740559
BTER: 100649548
SOC: 105208047
AEC: 105154186
ACEP: 105622679
HST: 105186645
LHU: 105671479
PGC: 109857477
NVI: 100117805
NVL: 108560837
ZNE: 110838823
CRG: 105323672
EPA: 110244148
ADF: 107341873
HMG: 100210586
SPAR: SPRG_05860
HMA: pNG7191(gfo2) rrnAC2929(gfo1) rrnAC3034(gfo6)
HHI: HAH_0191(gfo1) HAH_0291 HAH_5355(gfo4)
HWA: HQ_3202A
HWC: Hqrw_3764
NAT: NJ7G_0683
 » show all
Taxonomy
Reference
1
  Authors
Wissler, J.H.
  Title
D-Xylose:NADP oxidoreductase of arterial vessels and eye lens: a new enzyme and a final link in ATP-independent cycling of reducing eqivalents in aldose-polyol-ketose interconversion.
  Journal
Hoppe-Seyler's Z Physiol Chem 358:1300-1301 (1977)
Reference
2
  Authors
Wissler, J.H.
  Title
Direct spectrophotometric and specific quantitative determination of free and bound D-xylose by analytical application of a new enzyme, D-xylose:NADP-oxidoreductase.
  Journal
Fresenius' Z Anal Chem 290:179-180 (1978)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.179
IUBMB Enzyme Nomenclature: 1.1.1.179
ExPASy - ENZYME nomenclature database: 1.1.1.179
BRENDA, the Enzyme Database: 1.1.1.179
CAS: 83534-37-6

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