| Entry |
|
|---|
| Name |
UDP-glucose 6-dehydrogenase;
UDP-glucose dehydrogenase;
uridine diphosphoglucose dehydrogenase;
UDPG dehydrogenase;
UDPG:NAD oxidoreductase;
UDP-alpha-D-glucose:NAD oxidoreductase;
UDP-glucose:NAD+ oxidoreductase;
uridine diphosphate glucose dehydrogenase;
UDP-D-glucose dehydrogenase;
uridine diphosphate D-glucose dehydrogenase
|
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
UDP-alpha-D-glucose:NAD+ 6-oxidoreductase
|
|---|
| Reaction(IUBMB) |
UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 2 H+ [RN: R00286]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
Also acts on UDP-alpha-D-2-deoxyglucose.
|
|---|
| History |
EC 1.1.1.22 created 1961
|
|---|
| Pathway |
| ec00040 | Pentose and glucuronate interconversions |
| ec00053 | Ascorbate and aldarate metabolism |
| ec00520 | Amino sugar and nucleotide sugar metabolism |
|
|---|
| Orthology |
| K00012 | UDPglucose 6-dehydrogenase |
|
|---|
| Genes |
» show all
 |
|---|
| Reference |
|
|---|
| Authors |
Druzhinina TN, Kusov YY, Shibaev VN, Kochetkov NK, Biely P, Kucar S, Bauer S. |
|---|
| Title |
Uridine diphosphate 2-deoxyglucose. Chemical synthesis, enzymic oxidation and epimerization. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
KALCKAR HM, MAXWELL ES, STROMINGER JL. |
|---|
| Title |
Some properties of uridine diphosphoglucose dehydrogenase. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
STROMINGER JL, MAPSON LW. |
|---|
| Title |
Uridine diphosphoglucose dehydrogenase of pea seedlings. |
|---|
| Journal |
Biochem J 66:567-72 (1957) |
|---|
| Reference |
|
|---|
| Authors |
AXELROD J, KALCKAR HM, MAXWELL ES, STROMINGER JL. |
|---|
| Title |
Enzymatic formation of uridine diphosphoglucuronic acid. |
|---|
| Journal |
J Biol Chem 224:79-90 (1957) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.1.1.22 |
| ExPASy - ENZYME nomenclature database: | 1.1.1.22 |
|
|---|
