KEGG   ENZYME: 1.1.1.230Help
Entry
EC 1.1.1.230                Enzyme                                 

Name
3alpha-hydroxyglycyrrhetinate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase
Reaction(IUBMB)
3alpha-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + NADPH + H+ [RN:R04099]
Reaction(KEGG)
Substrate
3alpha-hydroxyglycyrrhetinate [CPD:C03930];
NADP+ [CPD:C00006]
Product
3-oxoglycyrrhetinate [CPD:C02943];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Highly specific to 3alpha-hydroxy derivatives of glycyrrhetinate and its analogues. Not identical to EC 1.1.1.50 3alpha-hydroxysteroid dehydrogenase (Si-specific).
History
EC 1.1.1.230 created 1990
Reference
1  [PMID:3164718]
  Authors
Akao T, Akao T, Hattori M, Namba T, Kobashi K.
  Title
Purification and properties of 3 alpha-hydroxyglycyrrhetinate dehydrogenase of Clostridium innocuum from human intestine.
  Journal
J Biochem (Tokyo) 103:504-7 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.230
IUBMB Enzyme Nomenclature: 1.1.1.230
ExPASy - ENZYME nomenclature database: 1.1.1.230
BRENDA, the Enzyme Database: 1.1.1.230
CAS: 114308-07-5

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