KEGG   ENZYME: 1.1.1.259Help
Entry
EC 1.1.1.259                Enzyme                                 

Name
3-hydroxypimeloyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3-hydroxypimeloyl-CoA:NAD+ oxidoreductase
Reaction(IUBMB)
3-hydroxypimeloyl-CoA + NAD+ = 3-oxopimeloyl-CoA + NADH + H+ [RN:R05305]
Reaction(KEGG)
Substrate
3-hydroxypimeloyl-CoA [CPD:C06714];
NAD+ [CPD:C00003]
Product
3-oxopimeloyl-CoA [CPD:C06715];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the anaerobic pathway of benzoate degradation in bacteria.
History
EC 1.1.1.259 created 2000
Pathway
ec00362  Benzoate degradation
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:8990279]
  Authors
Harwood CS, Gibson J.
  Title
Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?
  Journal
J Bacteriol 179:301-9 (1997)
DOI:10.1128/JB.179.2.301-309.1997
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.259
IUBMB Enzyme Nomenclature: 1.1.1.259
ExPASy - ENZYME nomenclature database: 1.1.1.259
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.259
BRENDA, the Enzyme Database: 1.1.1.259
CAS: 1187536-27-1

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