KEGG   ENZYME: 1.1.1.327Help
Entry
EC 1.1.1.327                Enzyme                                 

Name
5-exo-hydroxycamphor dehydrogenase;
F-dehydrogenase;
FdeH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
5-exo-hydroxycamphor:NAD+ oxidoreductase
Reaction(IUBMB)
5-exo-hydroxycamphor + NAD+ = bornane-2,5-dione + NADH + H+ [RN:R10021]
Reaction(KEGG)
Substrate
5-exo-hydroxycamphor [CPD:C03448];
NAD+ [CPD:C00003]
Product
bornane-2,5-dione;
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Contains Zn2+. Isolated from Pseudomonas putida, and involved in degradation of (+)-camphor.
History
EC 1.1.1.327 created 2012
Orthology
K19649  5-exo-hydroxycamphor dehydrogenase
Reference
1  [PMID:4351810]
  Authors
Rheinwald JG, Chakrabarty AM, Gunsalus IC
  Title
A transmissible plasmid controlling camphor oxidation in Pseudomonas putida.
  Journal
Proc Natl Acad Sci U S A 70:885-9 (1973)
DOI:10.1073/pnas.70.3.885
Reference
2  [PMID:2613690]
  Authors
Koga H, Yamaguchi E, Matsunaga K, Aramaki H, Horiuchi T
  Title
Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and  putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida.
  Journal
J Biochem 106:831-6 (1989)
Reference
3  [PMID:8334169]
  Authors
Aramaki H, Koga H, Sagara Y, Hosoi M, Horiuchi T
  Title
Complete nucleotide sequence of the 5-exo-hydroxycamphor dehydrogenase gene on the CAM plasmid of Pseudomonas putida (ATCC 17453).
  Journal
Biochim Biophys Acta 1174:91-4 (1993)
DOI:10.1016/0167-4781(93)90098-X
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.327
IUBMB Enzyme Nomenclature: 1.1.1.327
ExPASy - ENZYME nomenclature database: 1.1.1.327
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.327
BRENDA, the Enzyme Database: 1.1.1.327

DBGET integrated database retrieval system