KEGG   ENZYME: 1.1.1.341Help
Entry
EC 1.1.1.341                Enzyme                                 

Name
CDP-abequose synthase;
rfbJ (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
CDP-alpha-D-abequose:NADP+ 4-oxidoreductase
Reaction(IUBMB)
CDP-alpha-D-abequose + NADP+ = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ [RN:R08711]
Reaction(KEGG)
Substrate
CDP-alpha-D-abequose [CPD:C01788];
NADP+ [CPD:C00006]
Product
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose [CPD:C04297];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Isolated from Yersinia pseudotuberculosis [1,3] and Salmonella enterica [1,2].
History
EC 1.1.1.341 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
Orthology
K12455  CDP-abequose synthase
K19632  CDP-abequose synthase
Genes
STM: STM2089(rfbJ)
SEO: STM14_2583(rfbJ)
SEV: STMMW_21201
SEY: SL1344_2066(rfbJ)
SEM: STMDT12_C21110
SEJ: STMUK_2119(rfbJ)
SEB: STM474_2174(rfbJ)
SEF: UMN798_2257(rfbJ)
SETU: STU288_06830
SETC: CFSAN001921_06335
SHB: SU5_02683
SENS: Q786_10315
YPQ: DJ40_1357
YPR: BZ20_1044
 » show all
Taxonomy
Reference
1  [PMID:1724263]
  Authors
Kessler AC, Brown PK, Romana LK, Reeves PR
  Title
Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose.
  Journal
J Gen Microbiol 137:2689-95 (1991)
DOI:10.1099/00221287-137-12-2689
  Sequence
Reference
2  [PMID:2793832]
  Authors
Wyk P, Reeves P
  Title
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.
  Journal
J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989
  Sequence
[stm:STM2089]
Reference
3  [PMID:8071227]
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW.
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
  Journal
J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.341
IUBMB Enzyme Nomenclature: 1.1.1.341
ExPASy - ENZYME nomenclature database: 1.1.1.341
BRENDA, the Enzyme Database: 1.1.1.341

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