KEGG   ENZYME: 1.1.1.4Help
Entry
EC 1.1.1.4                  Enzyme                                 

Name
(R,R)-butanediol dehydrogenase;
butyleneglycol dehydrogenase;
D-butanediol dehydrogenase;
D-(-)-butanediol dehydrogenase;
butylene glycol dehydrogenase;
diacetyl (acetoin) reductase;
D-aminopropanol dehydrogenase;
1-amino-2-propanol dehydrogenase;
2,3-butanediol dehydrogenase;
D-1-amino-2-propanol dehydrogenase;
(R)-diacetyl reductase;
(R)-2,3-butanediol dehydrogenase;
D-1-amino-2-propanol:NAD+ oxidoreductase;
1-amino-2-propanol oxidoreductase;
aminopropanol oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(R,R)-butane-2,3-diol:NAD+ oxidoreductase
Reaction(IUBMB)
(R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+ [RN:R02946]
Reaction(KEGG)
Substrate
(R,R)-butane-2,3-diol [CPD:C03044];
NAD+ [CPD:C00003]
Product
(R)-acetoin [CPD:C00810];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also converts diacetyl into acetoin with NADH as reductant.
History
EC 1.1.1.4 created 1961 (EC 1.1.1.74 created 1972, incorporated 1976)
Pathway
ec00650  Butanoate metabolism
Orthology
K00004  (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase
Genes
SCE: YAL060W(BDH1) YAL061W(BDH2)
KLA: KLLA0_F00506g KLLA0_F00528g
KMX: KLMA_50016(BDH1) KLMA_50017(BDH2)
LTH: KLTH0D00616g
VPO: Kpol_1049p18
CGR: CAGL0D00198g
NCS: NCAS_0A07660(NCAS0A07660) NCAS_0A07670(NCAS0A07670)
NDI: NDAI_0H02050(NDAI0H02050) NDAI_0H02060(NDAI0H02060)
TPF: TPHA_0H03100(TPHA0H03100)
TBL: TBLA_0A04290(TBLA0A04290)
TDL: TDEL_0H04460(TDEL0H04460)
KAF: KAFR_0I00160(KAFR0I00160) KAFR_0I00170(KAFR0I00170)
PIC: PICST_89701(SOR1)
MBE: MBM_08711
ANI: AN9288.2
SRL: SOD_c19030(gutB) SOD_c29300(bdhA)
ETA: ETA_13710(adhB)
EPY: EpC_14410(adhB)
EPR: EPYR_01540(adhB)
EAM: EAMY_2196(adhB)
EAY: EAM_2119
ERJ: EJP617_32530(adhB)
PAU: PA14_10230(adh) PA14_10900(ydjL)
PNC: NCGM2_5301(ydjL) NCGM2_5356(adh)
PAEB: NCGM1900_0803(adh) NCGM1900_0860(ydjL)
PPU: PP_0552(bdhA)
PPF: Pput_0591
PPT: PPS_0549
PPI: YSA_06132
PPX: T1E_1534(bdhA)
PPUH: B479_03270
PPUT: L483_02890
PPUN: PP4_06240
PPUD: DW66_0566
PMON: X969_01185
PMOT: X970_01175
PPRC: PFLCHA0_c22200(bdhA1) PFLCHA0_c33950(bdhA2)
PSZ: PSTAB_2900(gutB)
PSR: PSTAA_3015(gutB)
PSEM: TO66_17355
AVN: Avin_41760(adh)
AVL: AvCA_41760(adh)
AVD: AvCA6_41760(adh)
ACX: Achr_8720(adh)
PALI: A3K91_1253
ACB: A1S_1705
ABM: ABSDF1934
ABY: ABAYE1943
ABN: AB57_1933
ABB: ABBFA_001791(gutB)
ABX: ABK1_2199
ABH: M3Q_2091
ABAD: ABD1_16970
ABAZ: P795_8705
ABAU: IX87_19415
ABAA: IX88_10480
ACC: BDGL_001066(bdh1)
ACI: ACIAD1021
ASJ: AsACE_p100043(bdhA)
MBS: MRBBS_2889(bdhA)
CYQ: Q91_0877
HAM: HALO2111
HBE: BEI_1438
ADI: B5T_00308
AXE: P40_01460
SALN: SALB1_2588
NME: NMB0604
NMP: NMBB_0667
NMH: NMBH4476_1586(gutB)
NMD: NMBG2136_0542(gutB)
NMM: NMBM01240149_1491(gutB)
NMS: NMBM01240355_0606(gutB)
NMA: NMA0808
NMW: NMAA_0457
NMX: NMA510612_0907(tdh)
NMC: NMC0547
NMN: NMCC_0550
NMT: NMV_1808
NMI: NMO_0489(tdh)
NGO: NGO0186
NGK: NGK_0240
NLA: NLA_16290
ECOR: SAMEA4412678_1404(gutB_1)
PSE: NH8B_2455
BVE: AK36_3830
BCJ: BCAM0035 BCAM1704(adh)
BCEW: DM40_4536
BCEO: I35_4035(tdh) I35_5575(adh)
BMUL: NP80_4483
BCT: GEM_3936
BDL: AK34_3888
BLAT: WK25_25120
BTEI: WS51_06130
BSTG: WT74_27610
BUK: MYA_4156
AAA: Acav_3447
DAC: Daci_2959
CTES: O987_13315
PCA: Pcar_0330(budX)
PPD: Ppro_1043
DPI: BN4_20346(bdhA)
SMD: Smed_4034
EAD: OV14_b0061(tdh)
AVI: Avi_7649
SHZ: shn_23065
OAH: DR92_2905
PDE: Pden_4980
PAMN: pAMV3p0150(bdhA)
DSH: Dshi_4159
SPHM: G432_04650
SPKC: KC8_08215
SSY: SLG_24940
SPHB: EP837_02951(butB)
AAY: WYH_01550(gutB)
ACR: Acry_2976
GXL: H845_1131
AZL: AZL_009040(gutB)
BSU: BSU06240(bdhA)
BSR: I33_0707
BSL: A7A1_0014
BSH: BSU6051_06240(bdhA)
BSUT: BSUB_00691(bdhA)
BSUL: BSUA_00691(bdhA)
BSUS: Q433_03525
BSS: BSUW23_03150(bdhA)
BST: GYO_0880
BSO: BSNT_06992(ydjL)
BSQ: B657_06240(bdhA)
BSX: C663_0642(bdhA)
BAY: RBAM_006650(ydjL)
BAQ: BACAU_0162(gutB1) BACAU_0636(bdhA1)
BYA: BANAU_0161(gutB1) BANAU_0576(bdhA)
BAML: BAM5036_0166(gutB) BAM5036_0585(bdhA)
BAMA: RBAU_0642(bdhA)
BAMN: BASU_0171(gutB1) BASU_0613(bdhA)
BAMB: BAPNAU_0162(gutB1) BAPNAU_0584(bdhA)
BAMT: AJ82_03695
BAMY: V529_05910(ydjL)
BMP: NG74_00192(gutB_1) NG74_00645(gutB_3)
BAO: BAMF_0161(gutB1) BAMF_0617(bdhA) BAMF_1833(gutB5)
BAZ: BAMTA208_00810(gutB1) BAMTA208_02880(bdhA) BAMTA208_08315(gutB5)
BQL: LL3_00661(bdhA) LL3_01924(gutB)
BXH: BAXH7_00164(gutB1) BAXH7_00605(ydjL) BAXH7_01695(gutB3)
BQY: MUS_0631(ydjL)
BHA: BH3949
BAN: BA_0675
BAR: GBAA_0675
BAT: BAS0641
BAI: BAA_0758
BANT: A16_07380
BANR: A16R_07440
BANS: BAPAT_0652
BANV: DJ46_5133
BCE: BC0668
BCA: BCE_0742 BCE_3248(gutB)
BCQ: BCQ_0741(adhB)
BCF: bcf_03455
BTK: BT9727_0585(adhB)
BTL: BALH_0616
BTT: HD73_0747
BTHI: BTK_03815
BTM: MC28_5399
BTG: BTB_c06890(bdhA)
BTI: BTG_17785
BTW: BF38_1920
BWW: bwei_4923(adhB)
BMYO: BG05_5251
BMYC: DJ92_3265
BCL: ABC0235
BPU: BPUM_2347
BPUM: BW16_12755
BPUS: UP12_11840
BMQ: BMQ_1884(bdhA)
BMD: BMD_1877(bdhA)
BMEG: BG04_4217
BAG: Bcoa_1775
BCOA: BF29_1719
BJS: MY9_0695
BACW: QR42_11925
BACY: QF06_02030
BACL: BS34A_07160(bdhA)
BALM: BsLM_0651
BGY: BGLY_0747
BBEV: BBEV_2737(bdhA)
OIH: OB3353
ANM: GFC28_352
AXL: AXY_04200
VPN: A21D_02492(gutB_1) A21D_03866(gutB_2)
BSE: Bsel_0599
SEP: SE2019
SER: SERP2032
SEPP: SEB_02026
SEPS: DP17_964
SHA: SH0605
SCA: SCA_2335(gutB)
SPAS: STP1_1419
SCAP: AYP1020_1631(gutB)
SSCH: LH95_01035
SSCZ: RN70_01255
BBE: BBR47_14610(ydjL)
PPY: PPE_03421
PPM: PPSC2_18175(adhB1)
PPO: PPM_3657(adhB1)
PPOL: X809_34265
PPOY: RE92_19025
LLA: L117145(butB)
LLK: LLKF_0924(butB)
LLS: lilo_0847(butB)
LLX: NCDO2118_0916(butB)
LLM: llmg_1642(butB)
LLJ: LG36_1429(butB)
SNT: SPT_0472
SND: MYY_0504
SPNN: T308_02110
SPP: SPP_0466
SSA: SSA_0572
SGO: SGO_0440
SCF: Spaf_1654
STJ: SALIVA_1693(gutB)
SSAH: HSISS4_01535(adhB2)
SIE: SCIM_1277
SIB: SIR_1468
SIU: SII_1455
LFE: LAF_0943
LFR: LC40_0618
LFF: LBFF_1013
LBH: Lbuc_2009
LAE: LBAT_1588
LME: LEUM_0912
LMM: MI1_04285
LMK: LMES_0836
LCI: LCK_00755
LKI: LKI_10090
LGS: LEGAS_1018(bdhA)
WCE: WS08_0968
WCT: WS74_1034
CBO: CBO2217
CBA: CLB_2156
CBY: CLM_2420
CBL: CLK_1657
CBK: CLL_A0664
CBB: CLD_2359
CBI: CLJ_B2427
CBT: CLH_0625
CBF: CLI_2266
CBM: CBF_2254
CBE: Cbei_1464
CBZ: Cbs_1464
CBEI: LF65_01539
CSB: CLSA_c40760(bdhA)
CLD: CLSPO_c22610(bdhA2)
CACE: CACET_c04920(bdhA)
CTYK: CTK_C16260
TPZ: Tph_c19660(bdhA)
MVA: Mvan_0788
MGI: Mflv_0125
MVQ: MYVA_0619
ASD: AS9A_4240
CDI: DIP2135
CDIP: ERS451417_02172(gutB)
CGY: CGLY_10510(bdhA)
NFA: NFA_30750
NFR: ERS450000_00990(gutB_1)
RER: RER_40280
REY: O5Y_18700
ROP: ROP_13310
REQ: REQ_44040
RFA: A3L23_01000(gutB_1) A3L23_02473 A3L23_03388(gutB_5) A3L23_03391(gutB_6)
RHU: A3Q40_01823(gutB_1)
GBR: Gbro_3625
SHY: SHJG_2464
SLAU: SLA_0209
ART: Arth_0880
ARM: ART_3026
AAI: AARI_31390(bdh)
KRH: KRH_22550
JDE: Jden_0784
BLIN: BLSMQ_1383
NML: Namu_1092
MMAR: MODMU_3886
AMN: RAM_36565
AMM: AMES_7013
AMZ: B737_7013
AMQ: AMETH_0716(adh) AMETH_1830(adh) AMETH_3638(adh)
PDX: Psed_3714
PSEE: FRP1_09150
PSEH: XF36_11545
ACTI: UA75_15100
ACAD: UA74_14510
AHG: AHOG_13650(gutB)
BAST: BAST_0421
LBA: Lebu_1842
MPW: MPR_2670
THS: TES1_0121
LOKI: Lokiarch_16160(gutB_1)
 » show all
Taxonomy
Reference
1  [PMID:13211662]
  Authors
STRECKER HJ, HARARY I.
  Title
Bacterial butylene glycol dehydrogenase and diacetyl reductase.
  Journal
J Biol Chem 211:263-70 (1954)
Reference
2  [PMID:13837186]
  Authors
TAYLOR MB, JUNI E.
  Title
Stereoisomeric specificities of 2,3-butanediol dehydrogenases.
  Journal
Biochim Biophys Acta 39:448-57 (1960)
DOI:10.1016/0006-3002(60)90197-9
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.4
IUBMB Enzyme Nomenclature: 1.1.1.4
ExPASy - ENZYME nomenclature database: 1.1.1.4
BRENDA, the Enzyme Database: 1.1.1.4
CAS: 37250-09-2

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