KEGG   ENZYME: 1.1.1.47Help
Entry
EC 1.1.1.47                 Enzyme                                 

Name
glucose 1-dehydrogenase [NAD(P)+];
D-glucose dehydrogenase (NAD(P)+);
hexose phosphate dehydrogenase;
beta-D-glucose:NAD(P)+ 1-oxidoreductase;
glucose 1-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-glucose:NAD(P)+ 1-oxidoreductase
Reaction(IUBMB)
D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+ [RN:R01520 R01521]
Reaction(KEGG)
Substrate
D-glucose [CPD:C00031];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
D-glucono-1,5-lactone [CPD:C00198];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
This enzyme has similar activity with either NAD+ or NADP+. cf. EC 1.1.1.118, glucose 1-dehydrogenase (NAD+) and EC 1.1.1.119, glucose 1-dehydrogenase (NADP+).
History
EC 1.1.1.47 created 1961, modified 2013
Pathway
ec00030  Pentose phosphate pathway
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00034  glucose 1-dehydrogenase
K13937  hexose-6-phosphate dehydrogenase
K22969  glucose 1-dehydrogenase
Genes
HSA: 9563(H6PD)
PTR: 100610187(H6PD)
PPS: 100993268(H6PD)
GGO: 101142424(H6PD)
PON: 100439160(H6PD)
NLE: 100588208(H6PD)
MCC: 710107(H6PD)
MCF: 102115057(H6PD)
CSAB: 103225643(H6PD)
RRO: 104663055(H6PD)
RBB: 108517948(H6PD)
CJC: 100386191(H6PD)
SBQ: 101028058(H6PD)
MMU: 100198(H6pd)
RNO: 298655(H6pd)
CGE: 100770090(H6pd)
NGI: 103733152(H6pd)
HGL: 101715539(H6pd)
CCAN: 109682341(H6pd)
OCU: 100357500(H6PD)
TUP: 102502621(H6PD)
CFA: 489642(H6PD)
AML: 100476557(H6PD)
UMR: 103666677(H6PD)
ORO: 101384136(H6PD)
FCA: 101098066(H6PD)
PTG: 102961280(H6PD)
AJU: 106984893(H6PD)
BOM: 102267212(H6PD)
BIU: 109570359(SPSB1)
PHD: 102329249
CHX: 102174863(H6PD)
OAS: 101114124(H6PD)
SSC: 110261091(H6PD)
CFR: 102515995(H6PD)
CDK: 105106995(H6PD)
BACU: 103015524(H6PD)
LVE: 103083939(H6PD)
OOR: 101277991(H6PD)
ECB: 100057646(H6PD)
EPZ: 103549083(H6PD)
EAI: 106826224(H6PD)
MYB: 102257733(H6PD)
MYD: 102767216(H6PD)
HAI: 109381286(H6PD)
RSS: 109455276(H6PD)
PALE: 102883153(H6PD)
LAV: 100663707(H6PD)
TMU: 101347869
MDO: 100009940(H6PD)
SHR: 100924302(H6PD)
OAA: 100082409
GGA: 428188(H6PD)
MGP: 100545189(H6PD)
CJO: 107323555(H6PD)
APLA: 101804195(H6PD)
ACYG: 106044323(H6PD)
TGU: 100228049(H6PD)
GFR: 102045426(H6PD)
FAB: 101813192(H6PD)
PHI: 102103089(H6PD)
PMAJ: 107213774(H6PD)
CCAE: 111938679(H6PD)
CCW: 104693331(H6PD)
FPG: 101919545(H6PD)
FCH: 102049461(H6PD)
CLV: 102095298(H6PD)
EGZ: 104133127(H6PD)
AAM: 106499029(H6PD)
ASN: 102369764(H6PD)
AMJ: 102562599(H6PD)
PSS: 102461733(H6PD)
CMY: 102932628(H6PD)
CPIC: 101951423(H6PD)
ACS: 100551772(h6pd)
PVT: 110073255(H6PD)
PBI: 103060486(H6PD)
GJA: 107110280(H6PD)
XTR: 100127695(h6pd)
NPR: 108787846(H6PD)
DRE: 569348(h6pd)
SGH: 107555977(h6pd)
CCAR: 109058644
IPU: 108271794(h6pd)
AMEX: 103045767(h6pd)
TRU: 101073312(h6pd)
LCO: 104920493(h6pd)
NCC: 104956358(h6pd)
MZE: 101464302(h6pd)
OLA: 101167199(h6pd)
XMA: 102223104(h6pd)
PRET: 103464522(h6pd)
NFU: 107385214(h6pd)
KMR: 108231149(h6pd)
CSEM: 103385698(h6pd)
LCF: 108889991(h6pd)
SDU: 111222868(h6pd)
HCQ: 109510667(h6pd)
BPEC: 110168637(h6pd)
MALB: 109959016(h6pd)
ELS: 105025428(h6pd)
SFM: 108933884(h6pd)
LCM: 102349672(H6PD)
CMK: 103184186(h6pd)
SPU: 590387(h6pd)
APLC: 110983992
SKO: 100372939(H6PD)
CRG: 105340439
MYI: 110446859
OBI: 106867532
LAK: 106166073
EPA: 110254168
ADF: 107345186
AQU: 105314200
ETA: ETA_30410(gdh)
EPY: EpC_32460(gdh)
EPR: EPYR_03494(gdh)
EAM: EAMY_3245(gdh)
EAY: EAM_0356(gdh)
ERJ: EJP617_07310(gdh)
PMR: PMI1532
PSB: Psyr_2297
PSYR: N018_10680
PFL: PFL_4100(gdh)
PPRC: PFLCHA0_c41590(ycdF)
PPRO: PPC_4201(gdh)
PFS: PFLU_2089
PFC: PflA506_1991(gdh)
PFB: VO64_1323
PMAN: OU5_1426
PSA: PST_3895
PSTT: CH92_19420
PSEM: TO66_21480
PANR: A7J50_2099
PSIL: PMA3_20195
LLO: LLO_1657
LOK: Loa_02537
MAH: MEALZ_1699(gdhI)
NWA: Nwat_1326
CGD: CR3_3948(gdh)
BCEW: DM40_22
BMU: Bmul_0907
BMJ: BMULJ_02351(gdh)
BMK: DM80_2596
BMUL: NP80_2531
BDL: AK34_698
BLAT: WK25_11565
BXE: Bxe_B0443
BXB: DR64_5777
BPH: Bphy_4761
PPNO: DA70_00090
PPNM: LV28_06185
PSPU: NA29_11455
PAPI: SG18_00475
BPT: Bpet0388(gdH)
AAV: Aave_1089
AAA: Acav_1071
RDP: RD2015_32
BBAG: E1O_11090
PBH: AAW51_3072(gdh)
TBD: Tbd_0924
DEU: DBW_0824
CCX: COCOR_00051(gcd)
SUR: STAUR_0105(gcd)
SCL: sce1528(gcd) sce7442
HOH: Hoch_0357
BJA: bll7185(gdh)
BRA: BRADO1396
BBT: BBta_6708
BRS: S23_11440(gdh)
AOL: S58_15170
MPO: Mpop_1521
MOR: MOC_2159
MCG: GL4_3181
RDE: RD1_3328
LVS: LOKVESSMR4R_01373(gdhIV)
SWI: Swit_0697
SPHD: HY78_23210
SPHM: G432_13485
GOX: GOX2015
GOH: B932_3505
GOY: GLS_c21270(gdh)
GDI: GDI2625(gdh)
GDJ: Gdia_0840
ACU: Atc_1440
BSU: BSU02830(ycdF) BSU03930(gdh)
BSH: BSU6051_02830(ycdF) BSU6051_03930(gdh)
BSUT: BSUB_00332(ycdF) BSUB_00444(gdh)
BSUL: BSUA_00332(ycdF) BSUA_00444(gdh)
BSS: BSUW23_01450(ycdF) BSUW23_02030(gdh)
BSO: BSNT_06602(ycdF) BSNT_06735(gdh)
BSQ: B657_02830(ycdF) B657_03930(gdh)
BSX: C663_0274(ycdF) C663_0386(gdh)
BLI: BL01382(gdh) BL01687(ycdF)
BLD: BLi00341(ycdF) BLi02566
BLH: BaLi_c03600(ycdF) BaLi_c26510(gdh)
BAY: RBAM_003090(ycdF) RBAM_004180(gdh)
BAQ: BACAU_0250(ycdF) BACAU_0354(gdh)
BYA: BANAU_0251(ycdF) BANAU_0354(gdh)
BAML: BAM5036_0264(ycdF) BAM5036_0377(gdh)
BAMA: RBAU_0281(ycdF) RBAU_0391(gdh)
BAMN: BASU_0266(ycdF) BASU_0376(gdh)
BAMB: BAPNAU_0249(ycdF) BAPNAU_0359(gdh)
BAMY: V529_02720(ycdF) V529_03790(gdh)
BMP: NG74_00288(ycdF) NG74_00395(gdh)
BAO: BAMF_0254(ycdF) BAMF_0361(gdh)
BQL: LL3_00265(ycdF) LL3_00376(gdh)
BXH: BAXH7_00268(ycdF) BAXH7_00379(gdh)
BQY: MUS_0266(ycdF) MUS_0382(gdh)
BAN: BA_4968(gdH)
BAR: GBAA_4968(gdH)
BAT: BAS4612
BAH: BAMEG_4999(gdH)
BAI: BAA_4978(gdH)
BANT: A16_49610
BANR: A16R_50240
BANS: BAPAT_4764
BANV: DJ46_3630(gdhB)
BCE: BC4715
BCA: BCE_4858(gdH)
BCZ: BCE33L4466(gdh) pE33L466_0368(gdh)
BCR: BCAH187_A4852(gdH)
BCB: BCB4264_A4828(gdH)
BCU: BCAH820_4834(gdH)
BCG: BCG9842_B0408(gdH)
BCQ: BCQ_4529(gdh)
BCX: BCA_4839(gdH)
BAL: BACI_c47130(gdh)
BNC: BCN_4625
BCF: bcf_23665
BCER: BCK_11600
BTK: BT9727_4448(gdh)
BTL: BALH_4289(gdh)
BTB: BMB171_C4353(gdH)
BTT: HD73_5025
BTC: CT43_CH4738(gdH)
BTM: MC28_3995
BTI: BTG_25270
BTW: BF38_478(gdhB)
BWW: bwei_0173(gdhB)
BMYO: BG05_1321(gdhB)
BMEG: BG04_285(gdhB) BG04_3132(gdhB) BG04_3338(gdhB)
BACL: BS34A_03380(ycdF) BS34A_04510(gdh)
BGY: BGLY_0339 BGLY_2840(gdh)
OIH: OB3183
SEP: SE1830
SER: SERP1839(gdh)
SEPP: SEB_01841
SEPS: DP17_781
SHA: SH0795
SHH: ShL2_00694(fabG_1)
SSP: SSP0656
SCA: SCA_1743(gdh)
SPAS: STP1_0733
SXO: SXYL_00698(gdh)
MCAK: MCCS_03100(gdhIV) MCCS_20860
ESI: Exig_0211
EAN: Eab7_0200(gdh)
PRI: PRIO_3737
LAC: LBA1098
LAD: LA14_1110
LAF: SD55_1108
LSL: LSL_0144(gdh)
LSI: HN6_00123(gdh)
LCA: LSEI_2180
LPAP: LBPC_2113
LCB: LCABL_23550(gdh)
LCS: LCBD_2346(yohF)
LCE: LC2W_2328(yohF)
LCW: BN194_23130(gdhII)
LRH: LGG_02189(gdh)
LRG: LRHM_2106
LRL: LC705_02185(gdh)
LRA: LRHK_2188(gdhB)
PPE: PEPE_0073
PPEN: T256_00370
EFA: EF2382(gdh)
EFL: EF62_2577
EFI: OG1RF_11820(gdh)
EFQ: DR75_1111
ENE: ENT_15570
EFC: EFAU004_01709(gdh)
EFAU: EFAU085_01732(gdh)
EFU: HMPREF0351_11664(gdh)
EFM: M7W_1207
EHR: EHR_10355
EMU: EMQU_1669(gdh)
EDU: LIU_09725
MPS: MPTP_0171
MPX: MPD5_0160
CRN: CAR_c18210(gdh)
CARC: NY10_2048
MTHN: 4412656_02890(fabG_14)
NFA: NFA_35140
NFR: ERS450000_00535(tdh_2)
RRT: 4535765_02289(ycdF_3)
SCO: SCO1335(2SCG61.17c)
SMA: SAVERM_1922(gdh)
SCT: SCAT_0262
SALS: SLNWT_0287
SALU: DC74_7660
SALL: SAZ_39525
STRE: GZL_04958
STRM: M444_05030
SMAL: SMALA_7201
SLX: SLAV_34555(gdh)
LMOI: VV02_16165
IDO: I598_0803(gutB)
NCA: Noca_4177
KFL: Kfla_3970
TFU: Tfu_2814
NDA: Ndas_2703
ACE: Acel_1681
NML: Namu_1837
AMD: AMED_1404(gdh)
AMN: RAM_07115
AMM: AMES_1395(gdh)
AMZ: B737_1396(gdh)
AMI: Amir_6870
SESP: BN6_82420
KAL: KALB_8550
ACTI: UA75_21135
ACAD: UA74_20640
AHG: AHOG_18420(tdh2)
MIL: ML5_2933
ACTN: L083_2762
AFS: AFR_14280
RXY: Rxyl_0551
CWO: Cwoe_1554
EYY: EGYY_17230(FabG)
GPA: GPA_17990
CBAC: JI75_06895
SYN: sll1709(gdh)
SYZ: MYO_111640(gdh)
SYY: SYNGTS_1154(gdh)
SYT: SYNGTI_1154(gdh)
SYS: SYNPCCN_1153(gdh)
SYQ: SYNPCCP_1153(gdh)
SYC: syc0030_d
SYG: sync_1918
SYR: SynRCC307_1928(gdh)
SYX: SynWH7803_0725(gdh)
SYND: KR52_12120
LET: O77CONTIG1_02855(ycdF)
CYT: cce_0222
GLJ: GKIL_4238(gdh)
ANA: all3836
AVA: Ava_1863
CALH: IJ00_01170
RCA: Rcas_2591
CAG: Cagg_3495
TTR: Tter_2119
PUV: PUV_21460(gdhII)
WCH: wcw_0442
SNG: SNE_A07830(gdh)
OTE: Oter_3349
RBA: RB10002(gcd) RB7294(gdh)
PIR: VN12_03790(ycdF) VN12_08675(yjmD) VN12_23100(gdhI)
PLM: Plim_4017
PLS: VT03_08360(ycdF) VT03_25955(yjmD)
PLH: VT85_00350(tdh)
FMR: Fuma_00966(yjmD) Fuma_03445 Fuma_04787(ycdF_2)
KST: KSMBR1_2588(adh1a)
PHM: PSMK_03410(gdh) PSMK_12480(gdh)
ACA: ACP_3015(gdh)
ABAS: ACPOL_2497
ABAC: LuPra_04555(gno_6) LuPra_05149(tdh_3)
CPI: Cpin_0947
MUC: MuYL_2741
MGOT: MgSA37_02942(gdh)
CHU: CHU_1661(gdh)
DFE: Dfer_1228
FAE: FAES_4123(gdh3)
HSW: Hsw_1304
ZPR: ZPR_1651
MARM: YQ22_12910
CBAL: M667_06450
CBAT: M666_06465
ZGA: ZOBELLIA_1102(gdhA)
EAO: BD94_3605
CHZ: CHSO_0978(gdhI)
NMV: NITMOv2_3999(gdh)
NJA: NSJP_2856
FAI: FAD_0737
CDIV: CPM_1797
PHO: PH1809(PH1809)
PFU: PF1853
TKO: TK0673
MPD: MCP_0058
RCI: RCIX1128(dhg)
HAL: VNG_0446G(gcd)
HSL: OE_1669F(gdh)
HHB: Hhub_1544(gdh)
HMA: rrnAC0917(sorD) rrnAC2741(ywfD2)
HHI: HAH_1550(sorD) HAH_4332(gdh)
NMO: Nmlp_1394(gdh)
HMU: Hmuk_2270
HWA: HQ_1663A(gdh)
HWC: Hqrw_1778(gdh)
HVO: HVO_1083(gdh)
HME: HFX_1090(gdh)
HLA: Hlac_0797
HTU: Htur_2582
NMG: Nmag_1146(gdh)
HBU: Hbut_1375
PYR: P186_1931
CMA: Cmaq_1304
TUZ: TUZN_0839
TTN: TTX_0329(gdh)
VDI: Vdis_0391
NGA: Ngar_c06980(gdh)
TAA: NMY3_00086(gdhI_1)
MARH: Mia14_0575
 » show all
Taxonomy
Reference
1  [PMID:810982]
  Authors
Banauch D, Brummer W, Ebeling W, Metz H, Rindfrey H, Lang H, Leybold K, Rick W, Staudinger HJ.
  Title
[A glucose dehydrogenase for the determination of glucose concentrations in body fluids (author's transl)]
  Journal
Z Klin Chem Klin Biochem 13:101-7 (1975)
Reference
2
  Authors
Brink, N.G.
  Title
Beef liver glucose dehydrogenase. 1. Purification and properties.
  Journal
Acta Chem Scand 7:1081-1089 (1953)
Reference
3  [PMID:2530]
  Authors
Pauly HE, Pfleiderer G
  Title
D-glucose dehydrogenase from Bacillus megaterium M 1286: purification, properties and structure.
  Journal
Hoppe Seylers Z Physiol Chem 356:1613-23 (1975)
Reference
4  [PMID:12981017]
  Authors
STRECKER HJ, KORKES S.
  Title
Glucose dehydrogenase.
  Journal
J Biol Chem 196:769-84 (1952)
Reference
5  [PMID:4392298]
  Authors
Thompson RE, Carper WR.
  Title
Glucose dehydrogenase from pig liver. I. Isolation and purification.
  Journal
Biochim Biophys Acta 198:397-406 (1970)
DOI:10.1016/0005-2744(70)90118-X
Reference
6  [PMID:21162]
  Authors
Fujita Y, Ramaley R, Freese E
  Title
Location and properties of glucose dehydrogenase in sporulating cells and spores  of Bacillus subtilis.
  Journal
J Bacteriol 132:282-93 (1977)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.47
IUBMB Enzyme Nomenclature: 1.1.1.47
ExPASy - ENZYME nomenclature database: 1.1.1.47
BRENDA, the Enzyme Database: 1.1.1.47
CAS: 9028-53-9

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