KEGG ENZYME: 1.1.1.53

ENZYME: 1.1.1.53

Entry

EC 1.1.1.53 Enzyme

Name

3alpha(or 20beta)-hydroxysteroid dehydrogenase;
cortisone reductase;
(R)-20-hydroxysteroid dehydrogenase;
20beta-hydroxy steroid dehydrogenase;
Delta4-3-ketosteroid hydrogenase;
20beta-hydroxysteroid dehydrogenase;
3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase;
NADH-20beta-hydroxysteroid dehydrogenase;
20beta-HSD

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase

Reaction(IUBMB)

androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ [RN:R04330]

Reaction(KEGG)

R04330;
(other) R04831 R04834 R04844 R04847

Substrate

androstan-3alpha,17beta-diol [CPD:C03852];
NAD+ [CPD:C00003]

Product

17beta-hydroxyandrostan-3-one [CPD:C03917];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

The 3alpha-hydroxy group or 20beta-hydroxy group of pregnane and androstane steroids can act as donor.

History

EC 1.1.1.53 created 1961, modified 1986

Pathway

ec00140

Steroid hormone biosynthesis

ec01100

Metabolic pathways

Orthology

K00038

3alpha(or 20beta)-hydroxysteroid dehydrogenase

Genes

XHY:	FZ025_06505

LEM:

LEN_2794

LUS:	E5843_13750

TBV:	H9L17_09835

VNA:	PN96_21715

PRE:	PCA10_29440

PSET:

THL1_4166

PPSH:

G5J76_09175

PRW:	PsycPRwf_0909

PSPG:

AK823_06640

PSYG:

AK825_06710

PSYY:

DLE54_04590

ATN:	FM020_06230

COLW:

A3Q33_18725

PHA:

PSHAa0891

PTN:	PTRA_a1023

PNG:	PNIG_a1074

ZAL:	AZF00_09860

HJA:	BST95_16185

HALC:

EY643_05850

HAA:	A5892_06475 A5892_07135

SDF:	ACG33_09105

SOK:	D0B54_05230

RIN:	ACS15_4336(fabG3) ACS15_4362

CNC:	CNE_BB1p08500(bacC)

CUU:	BKK79_02765

BUR:	Bcep18194_B1012 Bcep18194_B1510

BCJ:	BCAM1582 BCAM1939

BCEN:

DM39_3414 DM39_5921(fabG3)

BCEO:

I35_5441 I35_5764

BAC:	BamMC406_4338 BamMC406_4593

BMK:

DM80_3938

BCT:	GEM_3542 GEM_3731 GEM_4145

BCED:

DM42_6063 DM42_6378

BCEP:

APZ15_29245 APZ15_31375

BPYR:

ABD05_26060 ABD05_28010

BCON:

NL30_02625 NL30_04350

BDF:	WI26_21000 WI26_22930

BTEI:

WS51_05555

BPSL:

WS57_04565 WS57_06195

BMEC:

WJ16_26575 WJ16_28160

BSTL:

BBJ41_21130 BBJ41_23190

PMEG:

BPC:

BPER:

BPET:

BPEU:

BBM:	BN115_1129

BHO:

D560_0970

BHM:

D558_0953

BHZ:	ACR54_03739

BTRM:

SAMEA390648701966

BBRO:

BAU06_10380 BAU06_13355

BPDZ:

BBN53_04245

AXY:	AXYL_03129

AIS:	BUW96_05625

ACHR:

C2U31_27620

ODI:

ODI_R3001

AAA:

Acav_2984

VBO:	CKY39_24380

VAM:	C4F17_10110

HPSE:

HPF_00465(fabG2)

HYN:	F9K07_07760

DIH:	G7047_28880

MPT:

Mpe_A0883

METP:

C1M51_13615

DOE:	DENOEST_0155 DENOEST_2223(fabG) DENOEST_3326(fabG)

EBA:

ebA309

AZA:

AZKH_2309

THU:	AC731_008520

TCL:

Tchl_1579

TAK:	Tharo_2923

GME:	Gmet_2226 Gmet_2249

CFUS:

CYFUS_004796

MESO:

BSQ44_24850

MESP:

C1M53_08770

AAK:	AA2016_6632

RLE:

RL1197

RJG:	CCGE525_03295

KAI:	K32_24590(fabG3)

BJA:	bll0026(bll0026)

BJU:	BJ6T_00290

BJP:	RN69_00125

BIC:	LMTR13_26415

BOT:	CIT37_14680

BARH:

WN72_00580

VGO:	GJW-30_1_01699(cpnA_1) GJW-30_1_02841(fabG3_1)

METI:

DK427_23595

MMED:

Mame_00673(fabG3)

CEH:	CEW89_04480

CMAG:

CBW24_16305

MALG:

MALG_00957

YPAC:

CEW88_22185 CEW88_23330

TPRO:

Ga0080559_TMP4125

SALO:

EF888_11210

PALW:

PSAL_021450(fabG3)

NAR:	Saro_0512 Saro_3460 Saro_3667

NPP:	PP1Y_AT12924 PP1Y_AT13611 PP1Y_Mpl3491

NRE:	BES08_01630 BES08_04100 BES08_30480

NOV:	TQ38_027450

NOT:	C7W88_18590 C7W88_20490

NTD:	EGO55_02230 EGO55_02235 EGO55_04030 EGO55_05565 EGO55_14475 EGO55_15345

NGF:	FRF71_08450

NOG:	GKE62_06620 GKE62_15160

SPHK:

SKP52_13035(linX1)

SMAG:

AN936_15185

SMAZ:

LH19_03100

SGI:	SGRAN_1043(fabG3.1) SGRAN_3272(ucpA) SGRAN_3288(fabG3)

SWI:	Swit_0925 Swit_3288

SPHD:

HY78_03490 HY78_09115 HY78_21925

SPHM:

G432_09540 G432_18195 G432_19875 G432_20550

SSAN:

NX02_06305 NX02_07890

SPKC:

KC8_00535 KC8_14445

SPHA:

D3Y57_15355

SJP:	SJA_C1-18570(orfup) SJA_C2-03690 SJA_C2-05080

SCH:	Sphch_3068 Sphch_3070 Sphch_3469 Sphch_3499 Sphch_3501

SYB:	TZ53_08530

SBD:	ATN00_07880 ATN00_18860

SPMI:

K663_15970 K663_16040 K663_17441 K663_17556 K663_17651 K663_17736 K663_19773 K663_20588 K663_22183

SPHB:

EP837_03342 EP837_03402

SINB:

SIDU_10905 SIDU_11345 SIDU_11405

SPHT:

K426_23069 K426_28100 K426_28495 K426_29265

SHYD:

CJD35_06240 CJD35_06315

SCLO:

SCLO_1032300

SUFL:

FIL70_19475

SBAR:

H5V43_09850 H5V43_21135

CIJ:	WG74_12050

SPHG:

AZE99_15090

SFLA:

SPHFLASMR4Y_02490(benD)

SPHY:

CHN51_06210

BLAS:

BSY18_2740

BFW:	B5J99_04655

RDI:	CMV14_18875

SPHJ:

BSL82_04525 BSL82_04850

PALG:

HFP57_10445 HFP57_10490

SAND:

H3309_11125

ALH:	G6N82_09335 G6N82_10755

ELQ:	Ga0102493_111082 Ga0102493_11146

ERF:	FIU90_01720(fabG2)

PNS:	A9D12_03615

PORL:

BG023_11303

PHZ:	CHX26_01280

POT:	E2E27_02170

BTHV:

CQJ30_05665

BKO:	CKF48_08115

OIH:	OB0329 OB3314

OCN:	CUC15_03415 CUC15_10040 CUC15_19410

OCB:	CV093_03510 CV093_20940

AXL:	AXY_03970 AXY_05670

LGY:	T479_23465

LYZ:	DCE79_09825

LYG:	C1N55_20120

HHD:	HBHAL_1912

HLI:

HLI_05210

VNE:	CFK40_02885

VIM:	GWK91_10805 GWK91_10845

SJE:	AAV35_000655

PASA:

BAOM_2736

PSYH:

D0S48_12500 D0S48_18415

PSYO:

PB01_20610

PRD:	F7984_06510 F7984_12640

RUE:	DT065_05935

SALE:

EPH95_17095

NMK:	CHR53_06320

SEQO:

SE1039_01100

SSIF:

AL483_10050

SNL:	BJD96_13540

SFQ:	C7J90_03390

LGZ:	NCTC10812_00203(lvr)

PNP:	IJ22_27100

SIV:	SSIL_1656 SSIL_1982

SSIL:

SOLI23_08825 SOLI23_09255 SOLI23_13810

SOB:	CSE16_13975

PLN:	Plano_2785 Plano_2867

PKU:	AUO94_01820

PLL:	I858_009050

PDG:	BCM40_00895

PHC:	BBI08_11145 BBI08_11450

PMAR:

B0X71_03575

PPLA:

BBI15_10875

PFAE:

AJGP001_15800

PLX:	CW734_17225

KUR:	ASO14_1945

KZO:	NCTC404_01768(fabG3)

SPSY:

AZE41_00865

PGQ:	FK545_05410

PLAY:

DNR44_008330 DNR44_016720

LRE:

Lreu_1659

LRF:

LAR_1548

LRT:

LRI_0330

LRR:	N134_09120

LFN:	LF145_04490 LF145_07640

LBH:

Lbuc_0640

LBN:	LBUCD034_0661

LPAR:

FAM21731_00303

LCU:	PL11_001170 PL11_003070

LKF:	DNL43_02165 DNL43_04100

LHIL:

G8J22_00873(cpnA_3)

LBR:

LVIS_0166

LBK:	LVISKB_0165

LKO:	ABN16_07495

LSUA:

H3M12_05300

LHO:	LOOC260_102960

LOL:	LACOL_1341

LNN:	F0161_08745

LPD:	AYR62_00725 AYR62_14590

LMAE:

FGL90_03765 FGL90_03980

ESS:	ATZ33_02920

LGE:	C269_05050

WJO:	FOL01_0085

AUH:	AWM75_00685 AWM75_07335

JDA:	BW727_101599(fabG3)

JAR:	G7057_07460

JPO:	G7058_07520

MTU:	Rv2002(fabG3)

MTV:

RVBD_2002

MTC:

MT2058

MRA:	MRA_2018(fabG3-1)

MTF:	TBFG_12034

MTB:	TBMG_01984

MTK:	TBSG_01995

MTZ:	TBXG_001968

MTG:	MRGA327_12335

MTI:	MRGA423_12455

MTE:	CCDC5079_1849

MTUR:

CFBS_2112(fabG4)

MTL:	CCDC5180_1824

MTO:	MTCTRI2_2036(fabG3)

MTD:	UDA_2002(fabG3)

MTN:	ERDMAN_2205(fabG3)

MTJ:	J112_10705

MTUB:

MT7199_2033

MTUC:

J113_13820

MTUE:

J114_10710

MTX:	M943_10400

MTUH:

I917_14135

MTUL:

TBHG_01960

MTUT:

HKBT1_2108(fabG3)

MTUU:

HKBT2_2108(fabG3)

MTQ:	HKBS1_2113(fabG3)

MBO:	BQ2027_MB2025(fabG3)

MBB:	BCG_2019(fabG3)

MBT:	JTY_2014(fabG3)

MBM:	BCGMEX_2001(fabG3)

MBK:	K60_020750

MBX:

BCGT_1815

MAF:	MAF_20140(fabG3)

MMIC:

RN08_2216

MCE:	MCAN_20221(fabG3)

MCQ:	BN44_40286(fabG)

MCV:	BN43_31181(fabG)

MCX:	BN42_30300(fabG)

MCZ:	BN45_50280(fabG)

MPA:	MAP_1739c(fabG3) MAP_3577(fabG3)

MAO:	MAP4_0196 MAP4_2091

MAVI:

RC58_00925 RC58_10425

MAVU:

RE97_00930 RE97_10435

MAV:	MAV_2509 MAV_5136

MIT:	OCO_25040 OCO_49440 OCO_49620

MIA:	OCU_24910 OCU_49370 OCU_49550

MID:	MIP_03466 MIP_07512

MYO:	OEM_23470 OEM_49790

MCHI:

AN480_10595 AN480_12590 AN480_25755

MIR:	OCQ_23590 OCQ_50430 OCQ_50610

MMAL:

CKJ54_11350 CKJ54_23645

MLP:

MLM_0339

MSA:	Mycsm_03420

MUL:	MUL_1037(fabG3) MUL_1052

MMC:	Mmcs_2023 Mmcs_2711

MKM:	Mkms_2069 Mkms_2755

MJL:	Mjls_2006 Mjls_2741

MMI:	MMAR_0387(fabG3) MMAR_0402 MMAR_2981(fabG3_1)

MMAE:

MMARE11_03500(fabG3) MMARE11_03650 MMARE11_29030(fabG3_1)

MMM:	W7S_12085 W7S_24845

MLI:	MULP_00374(fabG3) MULP_00390 MULP_02842(hsd)

MKN:	MKAN_00800 MKAN_28930

MYV:	G155_12070 G155_12915 G155_12965 G155_16070

MYE:	AB431_05070 AB431_16440 AB431_22900

MYN:	MyAD_15035

MDX:	BTO20_12655 BTO20_16230 BTO20_21805 BTO20_21855 BTO20_22770 BTO20_33665

MSHG:

MSG_00321 MSG_00342 MSG_02794(fabG3)

MFJ:	MFLOJ_03720(fabG3) MFLOJ_31740 MFLOJ_31960

MGRO:

FZ046_20440

MXE:	MYXE_24870

MNV:	MNVI_41600

MPAG:

C0J29_02140 C0J29_02220 C0J29_15030 C0J29_26240

MNM:	MNVM_16720 MNVM_17100 MNVM_24720

MGOR:

H0P51_02085 H0P51_02170 H0P51_14260 H0P51_24465 H0P51_27850

MSM:	MSMEG_3515

MSG:	MSMEI_2506 MSMEI_3435(fabG3)

MSB:	LJ00_12770 LJ00_17490

MSN:	LI99_12770 LI99_17495

MSH:	LI98_12775 LI98_17500

MVA:	Mvan_2242 Mvan_3000

MGI:	Mflv_3281 Mflv_4104 Mflv_4505

MSP:	Mspyr1_26090 Mspyr1_34470 Mspyr1_39040

MCB:	Mycch_1986 Mycch_2878

MNE:	D174_15310

MGO:	AFA91_08275 AFA91_22235

MFT:	XA26_24780 XA26_26560 XA26_26650 XA26_32940

MPHL:

MPHLCCUG_02190 MPHLCCUG_02464(fabG3_1)

MVQ:	MYVA_1698(fabG3_1) MYVA_2160 MYVA_3063

MLL:	B1R94_04800 B1R94_13320

MRH:	MycrhN_4957

MTHN:

4412656_01659(cpnA_1)

MHAS:

MHAS_01896(fabG3) MHAS_02516(budC_1)

MDU:	MDUV_12030 MDUV_22710 MDUV_26530(fabG3)

MCHT:

MCHIJ_10070 MCHIJ_48900 MCHIJ_50700

MDR:	MDOR_20150

MAUU:

NCTC10437_01629(fabG3_2) NCTC10437_01670(fabG3_3) NCTC10437_02095(cpnA_2) NCTC10437_02864(fabG3_4)

MMAG:

MMAD_29420

MMOR:

MMOR_01060(fabG3) MMOR_34190 MMOR_41880

MFX:	MFAL_09760(fabG3) MFAL_26240

MAIC:

MAIC_28470 MAIC_41240 MAIC_46760

MIJ:	MINS_06760 MINS_06980 MINS_17180 MINS_26630(fabG3)

MALV:

MALV_14380

MTY:	MTOK_12840

MAB:

MAB_4680c

MMV:	MYCMA_2579

MABB:

MASS_4710

MABL:

MMASJCM_4737

MCHE:

BB28_23275

MIZ:	BAB75_26335

MSTE:

MSTE_04731 MSTE_04845

MJD:	JDM601_0114(fabG) JDM601_0150(fabG3) JDM601_3608(fabG3)

MTER:

4434518_00102(fabG_2) 4434518_00137(fabG3_2) 4434518_03587(fabG3_5)

MMIN:

MMIN_11380 MMIN_18930

MHIB:

MHIB_30100 MHIB_33520 MHIB_33870

ASD:	AS9A_1016 AS9A_3858(fabG3)

MKR:	MKOR_29100

CGT:	cgR_0065 cgR_2841

CGS:	C624_14475

CGG:	C629_14480

CKP:	ckrop_1446

CVT:	B843_09960

CCJZ:

ccrud_00215 ccrud_00420

CPRE:

Csp1_00440

NFA:	NFA_22600 NFA_33550 NFA_48060

NFR:	ERS450000_00698(fabG3)

NCY:	NOCYR_1615(fabG) NOCYR_2461 NOCYR_2947

NBR:	O3I_010095 O3I_018235

NNO:	NONO_c26260(fabG5) NONO_c48960 NONO_c58990(fabG2) NONO_c59020(fabG3)

NSL:	BOX37_08620 BOX37_14000

NSR:	NS506_04686(entA) NS506_05856 NS506_06833 NS506_06835 NS506_06837

NTP:	CRH09_27185

NOZ:	DMB37_01165 DMB37_30710 DMB37_39935

NOD:	FOH10_15135 FOH10_22775 FOH10_22785

NAH:	F5544_13290

NAD:	NCTC11293_02699(fabG3) NCTC11293_03775

RHA:	RHA1_ro01882 RHA1_ro05413

RER:	RER_11770 RER_34300 RER_49510 RER_51600

REY:	O5Y_05380 O5Y_23485 O5Y_24400

REB:	XU06_05625 XU06_23900 XU06_24820

ROP:	ROP_06510 ROP_15600 ROP_20270 ROP_27350 ROP_48550

ROA:	Pd630_LPD05001 Pd630_LPD06047 Pd630_LPD06502 Pd630_LPD07460 Pd630_LPD09005

REQ:	REQ_30210 REQ_44360 REQ_45140

RPY:	Y013_13845

RHB:	NY08_2135 NY08_3965

RHW:	BFN03_18320

RHS:	A3Q41_02365(cpnA)

RRZ:	CS378_16940

RQI:	C1M55_05830 C1M55_25055 C1M55_26020

RHOD:

AOT96_04810 AOT96_05830 AOT96_16260 AOT96_31780 AOT96_32015

RRT:	4535765_04493(cpnA)

RCR:	NCTC10994_02926

RTM:	G4H71_08550

GBR:

Gbro_2728

GPO:	GPOL_174p01110

GOR:	KTR9_0248 KTR9_2607 KTR9_4418

GTA:	BCM27_06705 BCM27_13840 BCM27_17645

GOM:	D7316_01206(fabG3) D7316_02578 D7316_02846

TPR:

Tpau_3804

TSM:	ASU32_21655 ASU32_23550

DIZ:	CT688_15730

DPC:	A6048_16505

TOY:	FO059_01530

SCO:	SCO4169(SCD66.06)

SALB:

XNR_5139

SMA:	SAVERM_3801

SGR:	SGR_4223 SGR_48t SGR_7091t

SGB:

WQO_14335

SCB:	SCAB_52021 SCAB_90611

SSX:	SACTE_6250

SVL:	Strvi_1003 Strvi_3325 Strvi_7622

SBH:	SBI_06326 SBI_09851

SHY:

SHJG_8575

SHO:	SHJGH_8335

SVE:	SVEN_1285 SVEN_1674 SVEN_3092

SDV:	BN159_0879 BN159_5018

STRP:

F750_7032

SFI:

SFUL_2902

SCI:	B446_16900

SRC:	M271_08610 M271_12330 M271_20795 M271_44275 M271_44440

SALU:

DC74_2167 DC74_3711 DC74_7418

SALL:

SAZ_11415 SAZ_19725 SAZ_38295

SLV:	SLIV_17530

SVT:	SVTN_07885 SVTN_16140 SVTN_35935 SVTN_35940

STRE:

GZL_01228 GZL_05178 GZL_06850

SCW:	TU94_25175

SLD:	T261_0450 T261_4799

SLC:	SL103_02785

STRM:

M444_10315 M444_15505

STRC:

AA958_21590 AA958_24355

SAMB:

SAM23877_1099

SPRI:

SPRI_4289

SCZ:	ABE83_21445

SCX:	AS200_01815 AS200_04425 AS200_26065

SRW:	TUE45_04311

SLE:	sle_17540(sle_17540)

SPAV:

Spa2297_15340

STRT:

A8713_30375

SCLF:

BB341_11290

SGS:	AVL59_44245

STSI:

A4E84_03035 A4E84_17350

SLS:	SLINC_3715

SNR:	SNOUR_05180 SNOUR_23770 SNOUR_31920

SPLU:

LK06_018905

STRD:

NI25_04545 NI25_21240

SAUO:

BV401_26735

SSIA:

A7J05_20295

SVU:	B1H20_13700

SPUN:

BFF78_24030

SGV:	B1H19_17970

SMAL:

SLAU:

SALF:

SALJ:

SLX:	SLAV_16565 SLAV_25060 SLAV_27205

STRO:

STRMOE7_17040

SFK:	KY5_1543 KY5_1993 KY5_3511c

SNZ:	DC008_14825

SGE:	DWG14_04802

SRJ:

SRO_4203

SLK:	SLUN_17075

SKY:	D0C37_00540 D0C37_27685

SDX:	C4B68_22895

SGD:	ELQ87_22165

SQZ:	FQU76_13180

SCYA:

EJ357_06005 EJ357_19805 EJ357_36955

SNQ:	CP978_31940

STIR:

DDW44_13050

SKA:	CP970_24780 CP970_32610 CP970_34985

SVN:	CP980_19440 CP980_22770 CP980_24785

SNK:	CP967_29825

SALW:

CP975_15050

SHAW:

CEB94_06210 CEB94_17810

SRK:	FGW37_13685

SFIC:

EIZ62_18960

SGAL:

CP966_15695

SSPO:

DDQ41_12955

SFY:	GFH48_23205

KSK:

KSE_72210

KAB:	B7C62_13655

STRI:

C7M71_025015

LXL:	KDY119_03415

MTS:

MTES_1749

MIO:	AOA12_02820

MIH:	BJP65_09795

MICR:

BMW26_01385

MHOS:

CXR34_15850

MLV:	CVS47_02095 CVS47_03327(fabG3)

RFS:	C1I64_07390

AGY:	ATC03_10780 ATC03_16405

CART:

PA27867_0918 PA27867_2445

CRY:	B7495_12160

CPHY:

B5808_20160

AUM:	AURMO_00041

MALK:

MalAC0309_0008

MYL:	C3E77_06050

SALA:

ESZ53_03420

HUM:	DVJ78_12150

HUW:	FPZ11_17545

GRY:	D7I44_01160

FRN:	F1C15_06910 F1C15_15640

GLN:	F1C58_09550 F1C58_11465

ARR:	ARUE_c18690(fabG2)

ARM:

ART_3462

ARL:	AFL94_13305

ARY:	ATC04_00435 ATC04_04660

ARZ:	AUT26_09460

ARU:	ASPU41_04875

ARQ:	BWQ92_06470

ARN:	CGK93_10125 CGK93_10210 CGK93_11865

ARX:	ARZXY2_2070

ARTH:

C3B78_08890 C3B78_08895

ARTP:

E5206_03925

ARI:	UM93_09645

ACH:

Achl_1690

APN:	Asphe3_01900

KFV:	AS188_03480

KRS:	EQG70_17555

SATK:

SA2016_1179

LMOI:

VV02_25060

IDO:	I598_0831(fabG3)

CET:	B8281_02615

CFI:	Celf_2643 Celf_3009

CGA:	Celgi_0772

CELZ:

E5225_03245

CELH:

GXP71_02745

OEK:	FFI11_002515 FFI11_005090

JME:	EEW87_016040

TEH:	GKE56_07440

PHW:	G7075_05715

SERW:

HALT:

MPH:

NCA:

NDK:	I601_0636(fabG3_2) I601_3497(fabG3_3)

NOO:	FE634_09480

NBE:	Back2_27010

NANO:

G5V58_09560 G5V58_21995

PSIM:

KR76_12265 KR76_13560 KR76_20075 KR76_23000 KR76_25085 KR76_26980

AEZ:	C3E78_15175

AEB:	C6I20_03580

KFL:	Kfla_1988 Kfla_2054

KQI:	F1D05_19155

NDA:	Ndas_4479 Ndas_4656

NAL:	B005_0300(fabG3)

TCU:

Tcur_3357

ACTW:

F7P10_03555 F7P10_03595 F7P10_03625 F7P10_05405 F7P10_23435 F7P10_34755

SRO:

Sros_1990

NOA:	BKM31_27550 BKM31_34675

FRI:	FraEuI1c_2671 FraEuI1c_3129

NML:

Namu_4881

BSD:	BLASA_2506

SACE:

GIY23_13220

SVI:	Svir_17570

AMD:	AMED_2425 AMED_3705

AMN:	RAM_12335 RAM_18865

AMM:	AMES_2398 AMES_3662

AMZ:	B737_2399 B737_3662

AOI:

AORI_2393

AJA:	AJAP_22395 AJAP_26860

AMQ:	AMETH_4959

AMYC:

CU254_09925 CU254_23490 CU254_25055

AMYB:

BKN51_04580 BKN51_15900

AAB:	A4R43_01475 A4R43_07370 A4R43_16645

AMYY:

YIM_13820(fabG7) YIM_21255(fabG14) YIM_29620 YIM_36910(fabG32)

AORI:

SD37_13025

PDX:

Psed_3898

PSEE:

FRP1_11655 FRP1_17245

PSEH:

XF36_15915

PSEQ:

AD006_19315 AD006_24700

PECQ:

AD017_04290 AD017_27155

PHH:	AFB00_02475 AFB00_24400

PAUT:

Pdca_02650(fabG3_1) Pdca_08390 Pdca_56640

APRE:

AMI:

KAL:

KPHY:

LED:	BBK82_29710 BBK82_33725 BBK82_37540 BBK82_38700

AHM:	TL08_03560 TL08_24265

AHG:	AHOG_04120(fabG3)

ALO:

CRK59559

PMAD:

BAY61_15985 BAY61_17870 BAY61_20745 BAY61_23405

STP:	Strop_2631

SAQ:

Sare_2828

MAU:	Micau_5142

MIL:

MICB:

MTUA:

MCAB:

VMA:	VAB18032_16785

AMS:	AMIS_21770 AMIS_27340 AMIS_58450

PLK:	CIK06_11160

PSUU:

Psuf_093040

VER:	HUT12_15715 HUT12_19755

CAI:

Caci_8769

BAST:

BAST_0247

BCOR:

BCOR_0200

BII:	BINDI_0136

BACT:

AB656_06565

SIJ:

SCIP_1264

EKE:	EK0264_09160

AYM:	YM304_13460

ATQ:	GH723_04550

EUZ:	DVS28_a0297

FLN:

FLA_0730

SHT:	KO02_11345

SPDR:

G6053_15640

BBD:	Belba_1029

SMON:

LBY:

SEON:

CPIP:

EVA:	EIB75_12330

MBN:

Mboo_0405

» show all

Reference

1 [PMID:718844]

Authors

Edwards CA, Orr JC.

Title

Comparison of the 3alpha-and 20beta-hydroxysteroid dehydrogenase activities of the cortisone reductase of Streptomyces hydrogenans.

Journal

Biochemistry 17:4370-6 (1978)
DOI:10.1021/bi00614a003

Reference

2 [PMID:14403761]

Authors

HUEBENER HJ, SAHRHOLZ FG

Title

[20 beta-Hydroxysteroid dehydrogenase. 2. Preparation and crystallization.]

Journal

Biochem Z 333:95-105 (1960)

Reference

3 [PMID:14403760]

Authors

HUEBENER HJ, SAHRHOLZ FG, SCHMIDT-THOME J, NESEMANN G, JUNK R

Title

[20 beta-Hydroxysteroid dehydrogenase, a new crystalline enzyme.]

Journal

Biochim Biophys Acta 35:270-2 (1959)
DOI:10.1016/0006-3002(59)90366-x

Reference

4 [PMID:13549484]

Authors

LYNN WS Jr, BROWN RH.

Title

The conversion of progesterone to androgens by testes.

Journal

J Biol Chem 232:1015-30 (1958)

Reference

5 [PMID:6936053]

Authors

Strickler RC, Covey DF, Tobias B.

Title

Study of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with an enzyme-generated affinity alkylator: dual enzyme activity at a single active site.

Journal

Biochemistry 19:4950-4 (1980)
DOI:10.1021/bi00563a002

Reference

6 [PMID:6928375]

Authors

Sweet F, Samant BR

Title

Bifunctional enzyme activity at the same active site: study of 3 alpha and 20 beta activity by affinity alkylation of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with 17-(bromoacetoxy)steroids.

Journal

Biochemistry 19:978-86 (1980)
DOI:10.1021/bi00546a023

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.53

IUBMB Enzyme Nomenclature:

1.1.1.53

ExPASy - ENZYME nomenclature database:

1.1.1.53

BRENDA, the Enzyme Database:

1.1.1.53

CAS:

9028-42-6

DBGET integrated database retrieval system