KEGG   ENZYME: 1.1.1.67Help
Entry
EC 1.1.1.67                 Enzyme                                 

Name
mannitol 2-dehydrogenase;
D-mannitol dehydrogenase;
mannitol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-mannitol:NAD+ 2-oxidoreductase
Reaction(IUBMB)
D-mannitol + NAD+ = D-fructose + NADH + H+ [RN:R00868]
Reaction(KEGG)
Substrate
D-mannitol [CPD:C00392];
NAD+ [CPD:C00003]
Product
D-fructose [CPD:C00095];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.67 created 1965
Pathway
ec00051  Fructose and mannose metabolism
Orthology
K00045  mannitol 2-dehydrogenase
Genes
SCE: YEL070W(DSF1) YNR073C(MAN2)
TDL: TDEL_0F00160(TDEL0F00160)
MGR: MGG_10334
TMN: UCRPA7_4806
SSCK: SPSK_04249
FGR: FGSG_03311
FPU: FPSE_10443
FVR: FVEG_08687
FOX: FOXG_09794
NHE: NECHADRAFT_61535
ANI: AN2815.2
ANG: ANI_1_1156034(An03g02430)
PTE: PTT_12770
PAE: PA2342(mtlD)
PAEV: N297_2416(mtlD)
PAEI: N296_2416(mtlD)
PAU: PA14_34360(mtlD)
PAP: PSPA7_2921(mtlD)
PAG: PLES_29611(mtlD)
PAF: PAM18_2699(mtlD)
PNC: NCGM2_3350(mtlD)
PAEB: NCGM1900_4191(mtlD)
PAEP: PA1S_13915
PAEM: U769_13525
PAEL: T223_15140
PAEU: BN889_02561(mtlD_2) BN889_02562(mtlD_3)
PAEG: AI22_19945
PAEC: M802_2413(mtlD)
PMY: Pmen_4472
PST: PSPTO_2703(uxuB)
PSB: Psyr_2436
PSYR: N018_15115
PFL: PFL_3074(mtlD)
PPRC: PFLCHA0_c31040(por)
PPRO: PPC_3102
PFS: PFLU_2741
PFC: PflA506_2955(mtlD)
PFW: PF1751_v1c24040(mtlD)
PFB: VO64_0068
PMAN: OU5_0309
PEN: PSEEN1989(mltD)
PSA: PST_2194(uxuB)
PSZ: PSTAB_2080(uxuB)
PSR: PSTAA_2224(uxuB)
PSTT: CH92_12220
PSEM: TO66_14925
PSOS: POS17_3079
PANR: A7J50_2618
PSIL: PMA3_13365
AVN: Avin_27360(mtlD)
AVL: AvCA_27360(mtlD)
AVD: AvCA6_27360(mtlD)
ACX: Achr_21900(mtlD)
SFR: Sfri_1903
PHA: PSHAb0208(uxuB)
PTN: PTRA_b0280(mtlK)
PEA: PESP_b0401(mtlK)
PART: PARC_b0300(mtlK)
PNG: PNIG_b0306(mtlK)
AMAL: I607_08135
AMAE: I876_08400
AMAO: I634_08505
AMAD: I636_08935
AMAI: I635_09205
AMAG: I533_08445
AMAC: MASE_08040
AAUS: EP12_08800
GAI: IMCC3135_11320(mtlK_1) IMCC3135_17960(mtlK_2)
CSA: Csal_0643
HEL: HELO_2490(mtlD)
HAM: HALO3432
SALN: SALB1_1875
BCN: Bcen_3727
BSEM: WJ12_27590
PLG: NCTC10937_02455(uxuB_xylB)
JAG: GJA_1469(DSF1)
HOH: Hoch_4543
MLO: mll4920
AMIH: CO731_00172(mtlK)
SME: SMc01501(mtlK)
SMX: SM11_chr2593(mtlK)
SMI: BN406_02289(mtlK)
SMEL: SM2011_c01501(mtlK)
SMER: DU99_13600
SMD: Smed_2353
SFD: USDA257_c49000(mtlK)
SIX: BSY16_153
SAME: SAMCFNEI73_Ch2808(mtlK)
EAD: OV14_3995
ATU: Atu4451(mtlK)
ARA: Arad_4011(mtlK)
AVI: Avi_3572(mtlK)
RET: RHE_CH03678(mtlK)
REC: RHECIAT_CH0003952(mtlK)
REL: REMIM1_CH03756(mtlK)
REP: IE4803_CH04065(mtlK)
REI: IE4771_CH04006(mtlK)
RLE: RL4214(mtlK)
RLG: Rleg_3748
RIR: BN877_II0296(mtlK)
RHL: LPU83_3711(mtlK)
RGA: RGR602_CH03592(mtlK)
RHN: AMJ98_CH03914(mtlK)
RPHA: AMC79_CH03868(mtlK)
RHT: NT26_2847(mtlK)
RHX: AMK02_CH03800(mtlK)
RHK: Kim5_CH04042(mtlK)
OAN: Oant_3848
OAH: DR92_2643(mtlK) DR92_4536(mtlK)
OCH: CES85_4067(mtlK)
VGO: GJW-30_1_02735(mtlK)
MAQU: Maq22A_c21585(mtlD)
PHL: KKY_3902
MMED: Mame_00720(mtlK_1)
HDI: HDIA_0693(mtlK_1) HDIA_4568(mtlK_2)
RSP: RSP_0096(mtlK)
RCP: RCAP_rcc02027(mtlK)
JAN: Jann_2907
RDE: RD1_1481(mtlK)
RLI: RLO149_c026740(mtlK)
PDE: Pden_4177
PAMN: pAMV3p0528(mtlK)
DSH: Dshi_0969(mtlK)
PGA: PGA1_c13160(mtlK)
PGL: PGA2_c13110(mtlK)
PGD: Gal_02088
PHP: PhaeoP97_01313(mtlK)
PPIC: PhaeoP14_01236(mtlK)
OAT: OAN307_c05610(mtlK)
OTM: OSB_12130(mtlK)
CID: P73_4304
MALG: MALG_04967
RHC: RGUI_0088
SPSE: SULPSESMR1_00922(mtlK)
LVS: LOKVESSMR4R_00809(mtlK)
AHT: ANTHELSMS3_00584(mtlK)
ZMO: ZMO1449
ZMN: Za10_1741
ZMM: Zmob_1661
ZMI: ZCP4_1683
ZMC: A265_01681(por)
ZMR: A254_01681(por)
GOX: GOX0849
GOH: B932_1330
GDI: GDI3276
GDJ: Gdia_3090
GXY: GLX_05980
GXL: H845_1712
KEU: S101446_00980(mtlK)
APK: APA386B_2545(mtlK)
ASZ: ASN_119(mtlK) ASN_1599(mtlK)
AZL: AZL_b04790(mtlK)
MAGQ: MGMAQ_0164(mtlK)
MPA: MAP_3809c
MIT: OCO_47430
MIA: OCU_47370
MID: MIP_07177
MYO: OEM_47610
MIR: OCQ_48460
MLP: MLM_1005
MMI: MMAR_0571
MMM: W7S_23790
MPHL: MPHLCCUG_00884(mtlK)
MTHN: 4412656_00770(por)
ASD: AS9A_4400
CGL: NCgl0108(Cgl0109)
CGB: cg0143(mtlD)
CGU: WA5_0108(MtlD)
CGT: cgR_0185
CGM: cgp_0143(mtlD)
CGJ: AR0_00845
CVA: CVAR_1686(mtlD)
CAMG: CAMM_05115
RER: RER_36900
REY: O5Y_16975
ROP: ROP_25060
RFA: A3L23_01445(mtlK_1) A3L23_03510(mtlK_2)
RHS: A3Q41_01912(mtlK) A3Q41_04720(por_3)
RHU: A3Q40_03969(por)
RRT: 4535765_01238(por)
SRT: Srot_2878
ACH: Achl_1716
AAI: AARI_01680(mtlK)
LMOI: VV02_13600
SERJ: SGUI_0027
BLIN: BLSMQ_2942
MPH: MLP_35300
KFL: Kfla_1360
SRO: Sros_3496
NML: Namu_3962
GOB: Gobs_2791
KRA: Krad_0300
PSEA: WY02_01650
PSEE: FRP1_10625
PSEH: XF36_09875
ACTN: L083_4978(uxuB)
AFS: AFR_25800
CTHE: Chro_4739
DGE: Dgeo_2866
RBA: RB2403(uxuB)
BXY: BXY_35570
BOA: Bovatus_02281(por)
BACC: BRDCF_p2236(por)
MBAS: ALGA_3510
PHE: Phep_3764
MARM: YQ22_16080
ZGA: ZOBELLIA_4263(uxuB)
EAO: BD94_0193
 » show all
Taxonomy
Reference
1
  Authors
Martinez, G., Barker, H.A. and Horecker, B.L.
  Title
A specific mannitol dehydrogenase from Lactobacillus brevis.
  Journal
J Biol Chem 238:1598-1603 (1963)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.67
IUBMB Enzyme Nomenclature: 1.1.1.67
ExPASy - ENZYME nomenclature database: 1.1.1.67
BRENDA, the Enzyme Database: 1.1.1.67
CAS: 9001-65-4

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