KEGG   ENZYME: 1.1.1.80Help
Entry
EC 1.1.1.80                 Enzyme                                 

Name
isopropanol dehydrogenase (NADP+);
isopropanol dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
propan-2-ol:NADP+ oxidoreductase
Reaction(IUBMB)
propan-2-ol + NADP+ = acetone + NADPH + H+ [RN:R01550]
Reaction(KEGG)
Substrate
propan-2-ol [CPD:C01845];
NADP+ [CPD:C00006]
Product
acetone [CPD:C00207];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.
History
EC 1.1.1.80 created 1972
Pathway
ec00640  Propanoate metabolism
Reference
1
  Authors
Hoshino, K.
  Title
Organism producing isopropanol from acetone. V. Enzymological [studies] on the oxidation-reduction of Lactobacillus brevis var. hofuensis. [in Japanese].
  Journal
Nippon Nogei Kagaku Kaishi 34:608-615 (1960)
Reference
2
  Authors
Hoshino, K. and Udagawa, K.
  Title
Organism producing isopropanol from acetone. VI. Isopropanol dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var. hofuensis. [in Japanese].
  Journal
Nippon Nogei Kagaku Kaishi 34:616-619 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.80
IUBMB Enzyme Nomenclature: 1.1.1.80
ExPASy - ENZYME nomenclature database: 1.1.1.80
BRENDA, the Enzyme Database: 1.1.1.80
CAS: 37250-18-3

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