KEGG   ENZYME: 1.1.1.82Help
Entry
EC 1.1.1.82                 Enzyme                                 

Name
malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(S)-malate:NADP+ oxidoreductase
Reaction(IUBMB)
(S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343]
Reaction(KEGG)
Substrate
(S)-malate [CPD:C00149];
NADP+ [CPD:C00006]
Product
oxaloacetate [CPD:C00036];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Activated by light.
History
EC 1.1.1.82 created 1972
Pathway
ec00620  Pyruvate metabolism
ec00710  Carbon fixation in photosynthetic organisms
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00051  malate dehydrogenase (NADP+)
Genes
ATH: AT5G58330
ALY: ARALYDRAFT_495948
CRB: 17876624
CSAT: 104726404 104735427 104761929
EUS: EUTSA_v10013555mg
BRP: 103845258 103851645 103856701
BNA: 106387162 106388230 106420432 106435756
BOE: 106303370 106317800 106320980 106323259 106326990 106335373 106336776
RSZ: 108828026 108842484 108842485 108844945 108847633
THJ: 104824214
CPAP: 110817875
CIT: 102622984
CIC: CICLE_v10031559mg
TCC: 18586537
GRA: 105780485
GHI: 107904294 107943658
GAB: 108457850
DZI: 111310364
EGR: 104421754
GMX: 100782567
GSJ: 114372222 114403577
PVU: PHAVU_007G140600g
VRA: 106772560
VAR: 108321953
VUN: 114192784
CCAJ: 109805341
MTR: MTR_1g090730
CAM: 101499870
LJA: Lj0g3v0300709.1(Lj0g3v0300709.1) Lj0g3v0300719.1(Lj0g3v0300719.1) Lj5g3v1699000.1(Lj5g3v1699000.1) Lj5g3v1699010.1(Lj5g3v1699010.1) Lj6g3v2017590.1(Lj6g3v2017590.1) Lj6g3v2017600.1(Lj6g3v2017600.1)
ADU: 107466651
AIP: 107618478
LANG: 109335149 109346097
FVE: 101299807
RCN: 112174171
PPER: 18785428
PMUM: 103331480
PAVI: 110760803
MDM: 103402801 103408309
PXB: 103937854 103938371 103951716
ZJU: 107413281
CSV: 101211170
CMO: 103489426
MCHA: 111010262
CMAX: 111467500
CMOS: 111449691
CPEP: 111801663
RCU: 8271083
JCU: 105648670
HBR: 110646716
MESC: 110619296 110623872
POP: 7479845
PEU: 105130696
JRE: 108983075 109011340
QSU: 111992093
VVI: 100247974
SLY: 543805(mdh) 778287(chMDH)
SPEN: 107004667 107015062
SOT: 102582818
CANN: 107850239
NTA: 107769200 107776723(chMDH) 107778629
NSY: 104222455
NTO: 104091726 104095070 104105470
NAU: 109209080 109216464
INI: 109190597
SIND: 105179602
OEU: 111380419 111384921
HAN: 110872415 110894838
LSV: 111911144
CCAV: 112524411
DCR: 108210185
BVG: 104884197
SOE: 110802517
CQI: 110698354 110726180
NNU: 104587331 104604574
PSOM: 113298704 113313201
OSA: 4346332
DOSA: Os08t0562100-01(Os08g0562100)
OBR: 102709764
BDI: 100837587
ATS: 109767185(LOC109767185)
SBI: 110436993 8057802
ZMA: 542374(mdh6)
SITA: 101754520 101775740
PDA: 103705497
EGU: 105055621
MUS: 103973387
DCT: 110099942
PEQ: 110020784
AOF: 109826016 109850210
ATR: 18432968
SMO: SELMODRAFT_175392 SELMODRAFT_270710
PPP: 112278796 112291394 112294853
CRE: CHLREDRAFT_192083(MDH5)
VCN: VOLCADRAFT_76573
MNG: MNEG_0778
OLU: OSTLU_42336
OTA: OT_ostta08g00930
BPG: Bathy04g00930
MIS: MICPUN_104869(NADP-MDH)
MPP: MICPUCDRAFT_57848(NADP-MDH)
CSL: COCSUDRAFT_36224
CVR: CHLNCDRAFT_29326
APRO: F751_0686
 » show all
Taxonomy
Reference
1  [PMID:5689906]
  Authors
Connelly JL, Danner DJ, Bowden JA.
  Title
Branched chain alpha-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid dehydrogenase.
  Journal
J Biol Chem 243:1198-203 (1968)
Reference
2  [PMID:4397919]
  Authors
Johnson HS.
  Title
NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis.
  Journal
Biochem Biophys Res Commun 43:703-9 (1971)
DOI:10.1016/0006-291X(71)90672-3
Reference
3  [PMID:4395182]
  Authors
Johnson HS, Hatch MD.
  Title
Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis.
  Journal
Biochem J 119:273-80 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.82
IUBMB Enzyme Nomenclature: 1.1.1.82
ExPASy - ENZYME nomenclature database: 1.1.1.82
BRENDA, the Enzyme Database: 1.1.1.82
CAS: 37250-19-4

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Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
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Gene (492)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (151)   
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   RefGene (224)   
Protein sequence (116)   
   UniProt (79)   
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   PMD (14)   
DNA sequence (240)   
   RefSeq(nuc) (12)   
   GenBank (117)   
   EMBL (111)   
3D Structure (2)   
   PDB (2)   
Protein domain (3)   
   InterPro (1)   
   Pfam (1)   
   PROSITE(DOC) (1)   
All databases (869)   

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