KEGG ENZYME: 1.1.1.82

ENZYME: 1.1.1.82

Entry

EC 1.1.1.82 Enzyme

Name

malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

(S)-malate:NADP+ oxidoreductase

Reaction(IUBMB)

(S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343]

Reaction(KEGG)

R00343

Substrate

(S)-malate [CPD:C00149];
NADP+ [CPD:C00006]

Product

oxaloacetate [CPD:C00036];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

Activated by light.

History

EC 1.1.1.82 created 1972

Pathway

ec00620

Pyruvate metabolism

ec00710

Carbon fixation in photosynthetic organisms

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K00051

malate dehydrogenase (NADP+)

Genes

ATH:

AT5G58330

ALY:

9300640

CRB:

17876624

CSAT:

104726404 104735427 104761929

EUS:	EUTSA_v10013555mg

BRP:	103845258 103851645 103856701

BNA:	106387162 106388230 106420432 106435756

BOE:	106317800 106326990 106335373

RSZ:	108828026 108842484 108842485 108844945 108847633

THJ:

104824214

CIT:

102622984

CIC:	CICLE_v10031559mg

TCC:

18586537

GRA:

105780485

GHI:	107904294 107943658

GAB:

DZI:

EGR:

GMX:

GSJ:	114372222 114403577

PVU:	PHAVU_007G140600g

VRA:

VAR:

VUN:

CCAJ:

MTR:	MTR_1g090730

CAM:

ADU:

AIP:

LANG:

FVE:

RCN:

PPER:

PMUM:

PAVI:

MDM:	103402801 103408309

PXB:	103937854 103938371 103951716

ZJU:

CSV:

CMO:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

JRE:	108983075 109011340

QSU:

111992093

VVI:

100247974

SLY:	778287(chMDH)

SPEN:

107015062

HAN:	110872415 110894838

LSV:

CCAV:

DCR:

BVG:

SOE:

CQI:	110698354 110726180

NNU:	104587331 104604574

OSA:

4346332

DOSA:

Os08t0562100-01(Os08g0562100)

OBR:

102709764

BDI:

100837587

ATS:	109767185(LOC109767185)

SBI:	110436993 8057802

ZMA:	542374(mdh6)

SITA:

PDA:

EGU:

MUS:

DCT:

PEQ:

AOF:

ATR:

SMO:	SELMODRAFT_175392 SELMODRAFT_270710

CRE:	CHLREDRAFT_192083(MDH5)

VCN:	VOLCADRAFT_76573

OLU:	OSTLU_42336

OTA:	OT_ostta08g00930

» show all

Reference

1 [PMID:5689906]

Authors

Connelly JL, Danner DJ, Bowden JA.

Title

Branched chain alpha-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid dehydrogenase.

Journal

J Biol Chem 243:1198-203 (1968)

Reference

2 [PMID:4397919]

Authors

Johnson HS.

Title

NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis.

Journal

Biochem Biophys Res Commun 43:703-9 (1971)
DOI:10.1016/0006-291X(71)90672-3

Reference

3 [PMID:4395182]

Authors

Johnson HS, Hatch MD.

Title

Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis.

Journal

Biochem J 119:273-80 (1970)
DOI:10.1042/bj1190273

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.82

IUBMB Enzyme Nomenclature:

1.1.1.82

ExPASy - ENZYME nomenclature database:

1.1.1.82

BRENDA, the Enzyme Database:

1.1.1.82

CAS:	37250-19-4

DBGET integrated database retrieval system