KEGG   ENZYME: 1.1.1.9Help
Entry
EC 1.1.1.9                  Enzyme                                 

Name
D-xylulose reductase;
NAD+-dependent xylitol dehydrogenase;
xylitol dehydrogenase (ambiguous);
erythritol dehydrogenase;
2,3-cis-polyol(DPN) dehydrogenase (C3-5);
pentitol-DPN dehydrogenase (ambiguous);
xylitol-2-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)
Reaction(IUBMB)
xylitol + NAD+ = D-xylulose + NADH + H+ [RN:R01896]
Reaction(KEGG)
Substrate
xylitol [CPD:C00379];
NAD+ [CPD:C00003]
Product
D-xylulose [CPD:C00310];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts as an L-erythrulose reductase.
History
EC 1.1.1.9 created 1961
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K05351  D-xylulose reductase
Genes
SCE: YLR070C(XYL2)
DHA: DEHA2A13992g
PIC: PICST_86924(XYL2)
PGU: PGUG_05726
SPAA: SPAPADRAFT_59053(XYL2.1) SPAPADRAFT_59888(XYL2.2)
LEL: LELG_05256
CAL: CAALFM_CR10840CA(XYL2)
CTP: CTRG_05796
COT: CORT_0D00360
CDU: CD36_35570(XYL2)
SLB: AWJ20_4946(SOR1)
NCR: NCU00891
NTE: NEUTE1DRAFT71383(NEUTE1DRAFT_71383)
MGR: MGG_01176
SSCK: SPSK_01795
TRE: TRIREDRAFT_81271(xdh1)
MBE: MBM_06974
ANG: ANI_1_2334074(An08g09380) ANI_1_4104(An12g00030)
ABE: ARB_04704
TVE: TRV_03145
SPO: SPBC1773.05c(tms1)
CNB: CNBA1020
ABP: AGABI1DRAFT113352(AGABI1DRAFT_113352)
ABV: AGABI2DRAFT192003(AGABI2DRAFT_192003)
SMW: SMWW4_v1c27000(ydjJ)
SMAR: SM39_2158
SERF: L085_15315
SGL: SG0610
SOD: Sant_3108
ETA: ETA_16670
PLU: plu1960
PAY: PAU_02204(ydjJ)
PSI: S70_17590
PSX: DR96_2471(xyl2)
MMK: MU9_3130
SPL: Spea_2286
SHL: Shal_2008
CSA: Csal_2609
SALN: SALB1_1584
BMA: BMAA1076
BMAL: DM55_4585
BMAE: DM78_3785
BMAQ: DM76_3537
BMAI: DM57_11320
BMAF: DM51_4751
BMAZ: BM44_4352
BMAB: BM45_3476
BPS: BPSS1235
BPSE: BDL_4525
BPSM: BBQ_4932
BPSU: BBN_4664
BPSD: BBX_3688
BPK: BBK_5875
BPSH: DR55_4057
BPSA: BBU_4822
BPSO: X996_4436
BUT: X994_5901
BTQ: BTQ_4460(sorD)
BTJ: BTJ_5441(sorD)
BTZ: BTL_3904
BTD: BTI_3735
BTV: BTHA_3976
BTHE: BTN_3757
BTHM: BTRA_4457(sord)
BTHA: DR62_3793
BTHL: BG87_3916
BOK: DM82_5405
BOC: BG90_5203
BCN: Bcen_5063
BCJ: BCAM0097
BCEO: I35_4106
BMUL: NP80_3465
BCED: DM42_5056
BCON: NL30_25000
BSEM: WJ12_21085
BMEC: WJ16_20345
BUL: BW21_5730
BPH: Bphy_6662
BFN: OI25_5778
CARE: LT85_3029
MLO: mlr4915
SME: SMc01992
SMER: DU99_14035
SMD: Smed_0849
ATU: Atu4318
RLE: pRL110382(sorD)
RLG: Rleg_6746
RHT: NT26_3942
SHZ: shn_17180
SNO: Snov_0847
MMED: Mame_01904
RDE: RD1_3623(xdh)
PDE: Pden_2163
DSH: Dshi_0551(xylD)
GDI: GDI3142
GDJ: Gdia_3230
GXL: H845_1385
RRU: Rru_A0252
RRF: F11_01275
BLJ: BLD_1700(tdh3)
BLK: BLNIAS_00276(tdh3)
BAD: BAD_0317
BADL: BADO_0324
BBRE: B12L_1575
BBRV: B689b_1676
BBRJ: B7017_1843
BBRC: B7019_1816
BBRS: BS27_1628
BBRD: BBBR_1646
BKS: BBKW_0346
BCAT: BBCT_0305
BPSC: BBPC_0333
 » show all
Taxonomy
Reference
1  [PMID:13692998]
  Authors
CHIANG C, KNIGHT SG.
  Title
A new pathway of pentose metabolism.
  Journal
Biochem Biophys Res Commun 3:554-9 (1960)
Reference
2  [PMID:13654257]
  Authors
HICKMAN J, ASHWELL G.
  Title
A sensitive and stereospecific enzymatic assay for xylulose.
  Journal
J Biol Chem 234:758-61 (1959)
Reference
3  [PMID:13789254]
  Authors
JAKOBY WB, FREDERICKS J.
  Title
Erythritol dehydrogenase from Aerobacter aerogenes.
  Journal
Biochim Biophys Acta 48:26-32 (1961)
DOI:10.1016/0006-3002(61)90511-X
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.9
IUBMB Enzyme Nomenclature: 1.1.1.9
ExPASy - ENZYME nomenclature database: 1.1.1.9
BRENDA, the Enzyme Database: 1.1.1.9
CAS: 9028-16-4

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