KEGG   ENZYME: 1.1.2.6Help
Entry
EC 1.1.2.6                  Enzyme                                 

Name
polyvinyl alcohol dehydrogenase (cytochrome);
PVA dehydrogenase;
PVADH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
polyvinyl alcohol:ferricytochrome-c oxidoreductase
Reaction(IUBMB)
polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+ [RN:R03136]
Reaction(KEGG)
Substrate
polyvinyl alcohol [CPD:C00980];
ferricytochrome c [CPD:C00125]
Product
oxidized polyvinyl alcohol [CPD:C01166];
ferrocytochrome c [CPD:C00126];
H+ [CPD:C00080]
Comment
A quinoprotein. The enzyme is involved in bacterial polyvinyl alcohol degradation. Some Gram-negative bacteria degrade polyvinyl alcohol by importing it into the periplasmic space, where it is oxidized by polyvinyl alcohol dehydrogenase, an enzyme that is coupled to the respiratory chain via cytochrome c. The enzyme contains a pyrroloquinoline quinone cofactor.
History
EC 1.1.2.6 created 1989 as EC 1.1.99.23, transferred 2010 to EC 1.1.2.6
Orthology
K05889  polyvinyl alcohol dehydrogenase (cytochrome)
Genes
XFA: XF_2259
XFT: PD_1299
XFN: XfasM23_1384
XFF: XFLM_00585
XFL: P303_06185
XFS: D934_06040
XTW: AB672_07465
XCC: XCC4080
XCB: XC_4171
XCA: xcc-b100_4282(mxaF2)
XCP: XCR_0167
XCV: XCV4300
XAX: XACM_4071
XAC: XAC4199
XOO: XOO0329
XOM: XOO0301(XOO0301)
XOP: PXO_02746
XOR: XOC_0353
XPH: XppCFBP6546_13360(XppCFBP6546P_13360)
BCT: GEM_3393
EBA: p2A321(pvaA)
SCL: sce5403
BJA: bll5504
BRAD: BF49_6141
PZU: PHZ_c0057
SGI: SGRAN_2681(pvadh)
SWI: Swit_1323
SPHD: HY78_19955
ANH: A6F65_02146(pvaA)
ADO: A6F68_02640(pvaA)
SUS: Acid_5713
ABAC: LuPra_02536(pvaA)
SLI: Slin_2985
 » show all
Taxonomy
Reference
1  [PMID:3513704]
  Authors
Shimao M, Ninomiya K, Kuno O, Kato N, Sakazawa C.
  Title
Existence of a novel enzyme, pyrroloquinoline quinone-dependent polyvinyl alcohol dehydrogenase, in a bacterial symbiont, Pseudomonas sp. strain VM15C.
  Journal
Appl Environ Microbiol 51:268-75 (1986)
Reference
2  [PMID:16347841]
  Authors
Shimao M, Onishi S, Kato N, Sakazawa C.
  Title
Pyrroloquinoline Quinone-Dependent Cytochrome Reduction in Polyvinyl Alcohol-Degrading Pseudomonas sp. Strain VM15C.
  Journal
Appl Environ Microbiol 55:275-278 (1989)
Reference
3  [PMID:18343342]
  Authors
Mamoto R, Hu X, Chiue H, Fujioka Y, Kawai F
  Title
Cloning and expression of soluble cytochrome c and its role in polyvinyl alcohol  degradation by polyvinyl alcohol-utilizing Sphingopyxis sp. strain 113P3.
  Journal
J Biosci Bioeng 105:147-51 (2008)
DOI:10.1263/jbb.105.147
Reference
4  [PMID:16804170]
  Authors
Hirota-Mamoto R, Nagai R, Tachibana S, Yasuda M, Tani A, Kimbara K, Kawai F
  Title
Cloning and expression of the gene for periplasmic poly(vinyl alcohol) dehydrogenase from Sphingomonas sp. strain 113P3, a novel-type quinohaemoprotein  alcohol dehydrogenase.
  Journal
Microbiology 152:1941-9 (2006)
DOI:10.1099/mic.0.28848-0
  Sequence
Reference
5  [PMID:18214469]
  Authors
Hu X, Mamoto R, Fujioka Y, Tani A, Kimbara K, Kawai F
  Title
The pva operon is located on the megaplasmid of Sphingopyxis sp. strain 113P3 and is constitutively expressed, although expression is enhanced by PVA.
  Journal
Appl Microbiol Biotechnol 78:685-93 (2008)
DOI:10.1007/s00253-008-1348-y
Reference
6  [PMID:19590867]
  Authors
Kawai F, Hu X
  Title
Biochemistry of microbial polyvinyl alcohol degradation.
  Journal
Appl Microbiol Biotechnol 84:227-37 (2009)
DOI:10.1007/s00253-009-2113-6
Other DBs
ExplorEnz - The Enzyme Database: 1.1.2.6
IUBMB Enzyme Nomenclature: 1.1.2.6
ExPASy - ENZYME nomenclature database: 1.1.2.6
BRENDA, the Enzyme Database: 1.1.2.6

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