KEGG   ENZYME: 1.1.3.19Help
Entry
EC 1.1.3.19                 Enzyme                                 

Name
4-hydroxymandelate oxidase (decarboxylating);
L-4-hydroxymandelate oxidase (decarboxylating);
(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase;
(S)-4-hydroxymandelate:oxygen 1-oxidoreductase;
4-hydroxymandelate oxidase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
(S)-4-hydroxymandelate:oxygen 1-oxidoreductase (decarboxylating)
Reaction(IUBMB)
(S)-4-hydroxymandelate + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2 [RN:R02673]
Reaction(KEGG)
Substrate
(S)-4-hydroxymandelate [CPD:C03198];
O2 [CPD:C00007]
Product
4-hydroxybenzaldehyde [CPD:C00633];
CO2 [CPD:C00011];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD), requires Mn2+. The enzyme from the bacterium Pseudomonas putida is involved in the degradation of mandelate.
History
EC 1.1.3.19 created 1984, modified 2014
Pathway
ec00627  Aminobenzoate degradation
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:976259]
  Authors
Bhat SG, Vaidyanathan CS.
  Title
Purification and properties of L-4-hydroxymandelate oxidase from Pseudomonas convexa.
  Journal
Eur J Biochem 68:323-31 (1976)
DOI:10.1111/j.1432-1033.1976.tb10818.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.3.19
IUBMB Enzyme Nomenclature: 1.1.3.19
ExPASy - ENZYME nomenclature database: 1.1.3.19
BRENDA, the Enzyme Database: 1.1.3.19
CAS: 60976-30-9

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