KEGG   ENZYME: 1.1.5.8Help
Entry
EC 1.1.5.8                  Enzyme                                 

Name
quinate dehydrogenase (quinone);
NAD(P)+-independent quinate dehydrogenase;
quinate:pyrroloquinoline-quinone 5-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With a quinone or similar compound as acceptor
BRITE hierarchy
Sysname
quinate:quinol 3-oxidoreductase
Reaction(IUBMB)
quinate + quinone = 3-dehydroquinate + quinol [RN:R09322]
Reaction(KEGG)
R09322 > R01873;
(other) R02415
Show
Substrate
quinate [CPD:C00296];
quinone [CPD:C15602]
Product
3-dehydroquinate [CPD:C00944];
quinol [CPD:C15603]
Comment
The enzyme is membrane-bound. Does not use NAD(P)+ as acceptor. Contains pyrroloquinoline-quinone.
History
EC 1.1.5.8 created 1992 as EC 1.1.99.25, modified 2004, transferred 2010 to EC 1.1.5.8
Pathway
ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01130  Biosynthesis of antibiotics
Orthology
K05358  quinate dehydrogenase (quinone)
Genes
ENT: Ent638_1963
ENC: ECL_02057
ENO: ECENHK_10750
ECLO: ENC_12540
EEC: EcWSU1_02121(quiA)
ENL: A3UG_10890
ECLG: EC036_20890
ECLE: ECNIH2_10510
ECLN: ECNIH4_12015
ECLI: ECNIH5_09660
ECLX: LI66_09885
ECLY: LI62_10650
ECLZ: LI64_09950
ESA: ESA_02962
CSK: ES15_3040(quiA)
KPN: KPN_01951
KPU: KP1_3018
KPP: A79E_2297
KPT: VK055_0527(quiA)
KPE: KPK_2122(quiA_1) KPK_2398(quiA_2)
KPR: KPR_2988(qumA)
KPJ: N559_2336
KPX: PMK1_04294(quiA)
KPNU: LI86_11620
KPNK: BN49_3047(qumA)
PSTS: E05_26620
SPE: Spro_2415
SRL: SOD_c22460(quiA)
SPLY: Q5A_012575(quiA)
SMAR: SM39_2615
SERF: L085_12765
RAA: Q7S_24111
PCT: PC1_2746
SOD: Sant_2284
ETA: ETA_10330(quiA)
EPY: EpC_10520(quiA)
EPR: EPYR_01114(quiA)
EAM: EAMY_2572(quiA)
EAY: EAM_2469(qumA)
EBI: EbC_33710(quiA)
ERJ: EJP617_00370(quiA)
EGE: EM595_2669(quiA)
PAM: PANA_2853(qumA)
PLF: PANA5342_1191(qumA)
PAJ: PAJ_2140(qumA)
PVA: Pvag_2273(quiA)
PSTW: DSJ_07565
TPTY: NCTC11468_02741(quiA_1) NCTC11468_02742(quiA_2)
LGU: LG3211_4849(quiA)
PRE: PCA10_30500(quiA)
PCQ: PcP3B5_21730(quiA)
PPU: PP_3569(quiA)
PPF: Pput_2205
PPT: PPS_3064
PPI: YSA_00152
PPX: T1E_2295(qumA)
PPUH: B479_15240
PPUT: L483_18690
PPUN: PP4_21570(quiA) PP4_22620(quiA) PP4_30900(quiA)
PPUD: DW66_3333
PMOT: X970_14345
PST: PSPTO_2568(gcd-1)
PSP: PSPPH_2927(quiA)
PFL: PFL_5668(quiA)
PPRC: PFLCHA0_c56200(quiA)
PPRO: PPC_5613
PFS: PFLU_2304
PFW: PF1751_v1c20540(gcd)
PFB: VO64_5531
PEN: PSEEN2918(quiA)
PPUU: PputUW4_04960(quiA)
PSES: PSCI_2560
PSEM: TO66_28735
PSEC: CCOS191_2952(qumA)
PSOS: POS17_5600
PSIL: PMA3_27675
ACB: A1S_1880
ABM: ABSDF2011(quiA)
ABY: ABAYE1685(quiA)
ABN: AB57_2214
ABAD: ABD1_19010(quiA)
ABAZ: P795_7610
ABAU: IX87_20860
ABAA: IX88_11575
ACC: BDGL_001359(quiA)
ACI: ACIAD1716(quiA)
ADI: B5T_01333
AXE: P40_06280
BMEC: WJ16_18565
PLG: NCTC10937_02880(quiA)
BHO: D560_0057
BHM: D558_0055
BHZ: ACR54_01234(quiA_1)
PUT: PT7_3097
AMIM: MIM_c02450 MIM_c38430(quiA)
AAA: Acav_1444
AMIH: CO731_02353(quiA)
ATU: Atu3354
AVI: Avi_5248
RLE: RL3832(quiA)
RLG: Rleg_3417
RIR: BN877_II1480(qumA)
PAMN: pAMV3p0147(quiA)
DSH: Dshi_2294
KRO: BVG79_p1000055(gcd)
SPHM: G432_16325
GOX: GOX1857
GOY: GLS_c14360(quiA1) GLS_c19740(quiA2)
APK: APA386B_1016(gcd)
ASZ: ASN_2084
 » show all
Taxonomy
Reference
1  [PMID:3044290]
  Authors
van Kleef MA, Duine JA.
  Title
Bacterial NAD(P)-independent quinate dehydrogenase is a quinoprotein.
  Journal
Arch Microbiol 150:32-6 (1988)
Reference
2  [PMID:14586099]
  Authors
Adachi O, Tanasupawat S, Yoshihara N, Toyama H, Matsushita K.
  Title
3-dehydroquinate production by oxidative fermentation and further conversion of 3-dehydroquinate to the intermediates in the shikimate pathway.
  Journal
Biosci Biotechnol Biochem 67:2124-31 (2003)
DOI:10.1271/bbb.67.2124
Reference
3  [PMID:15598527]
  Authors
Vangnai AS, Toyama H, De-Eknamkul W, Yoshihara N, Adachi O, Matsushita K
  Title
Quinate oxidation in Gluconobacter oxydans IFO3244: purification and characterization of quinoprotein quinate dehydrogenase.
  Journal
FEMS Microbiol Lett 241:157-62 (2004)
DOI:10.1016/j.femsle.2004.10.014
Other DBs
ExplorEnz - The Enzyme Database: 1.1.5.8
IUBMB Enzyme Nomenclature: 1.1.5.8
ExPASy - ENZYME nomenclature database: 1.1.5.8
BRENDA, the Enzyme Database: 1.1.5.8
CAS: 115299-99-5

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