KEGG   ENZYME: 1.1.98.2Help
Entry
EC 1.1.98.2                 Enzyme                                 

Name
glucose-6-phosphate dehydrogenase (coenzyme-F420);
coenzyme F420-dependent glucose-6-phosphate dehydrogenase;
F420-dependent glucose-6-phosphate dehydrogenase;
FGD1;
Rv0407;
F420-dependent glucose-6-phosphate dehydrogenase 1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other, known, physiological acceptors
BRITE hierarchy
Sysname
D-glucose-6-phosphate:F420 1-oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + oxidized coenzyme F420 = 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420 [RN:R09550]
Reaction(KEGG)
Substrate
D-glucose 6-phosphate [CPD:C00092];
oxidized coenzyme F420 [CPD:C00876]
Product
6-phospho-D-glucono-1,5-lactone [CPD:C01236];
reduced coenzyme F420 [CPD:C01080]
Comment
The enzyme is very specific for D-glucose 6-phosphate. No activity with NAD+, NADP+, FAD and FMN [1].
History
EC 1.1.98.2 created 2010 as EC 1.1.99.34, transferred 2011 to EC 1.1.98.2
Orthology
K15510  coenzyme F420-dependent glucose-6-phosphate dehydrogenase
Genes
DEI: C4375_12610(fgd)
MTU: Rv0407(fgd1)
MTV: RVBD_0407
MTC: MT0420(fgd)
MRA: MRA_0413(fgd1)
MTF: TBFG_10412
MTB: TBMG_00408
MTK: TBSG_00411
MTZ: TBXG_000406
MTI: MRGA423_02565
MTUR: CFBS_0423(fgd1)
MTO: MTCTRI2_0410(fgd1)
MTD: UDA_0407(fgd1)
MTN: ERDMAN_0449(fgd1)
MTUE: J114_02165
MTUL: TBHG_00403
MTUT: HKBT1_0423(fgd1)
MTUU: HKBT2_0423(fgd1)
MTQ: HKBS1_0423(fgd1)
MBO: BQ2027_MB0415(fgd1)
MBB: BCG_0446(fgd1)
MBT: JTY_0416(fgd1)
MBM: BCGMEX_0417(fgd1)
MBX: BCGT_0178
MAF: MAF_04090(fgd1)
MMIC: RN08_0458
MCE: MCAN_04051(fgd1)
MCQ: BN44_10448(fgd)
MCV: BN43_10440(fgd)
MCX: BN42_20128(fgd)
MCZ: BN45_10445(fgd)
MLE: ML0269
MLB: MLBr00269
MPA: MAP_3884
MAO: MAP4_3999
MAVI: RC58_19860
MAVU: RE97_19915
MAV: MAV_4761
MIT: OCO_46700
MIA: OCU_46430
MID: MIP_07069
MYO: OEM_46820
MIR: OCQ_47730
MMAL: CKJ54_22215(fgd)
MLP: MLM_3925
MUL: MUL_2814(fgd1)
MMC: Mmcs_0532
MKM: Mkms_0544
MJL: Mjls_0522
MMI: MMAR_0709(fgd1)
MMAE: MMARE11_06580(fgd1)
MMM: W7S_23445
MLI: MULP_00708(fgd1)
MHAD: B586_00345
MSG: MSMEI_0761(fgd1)
MVA: Mvan_0698
MGI: Mflv_0211
MPHL: MPHLCCUG_04650(fgd_8)
MVQ: MYVA_0536
MTHN: 4412656_00482(fgd1_1) 4412656_01048(fgd1_2)
MAB: MAB_4230c
MABB: MASS_4265
MCHE: BB28_21790
MSTE: MSTE_04406(fgd)
MJD: JDM601_0380(fgd1)
MTER: 4434518_00378(fgd1_2)
ASD: AS9A_0529
NFA: NFA_53550
NFR: ERS450000_04516(fgd1_4)
NCY: NOCYR_5193(fgd)
NNO: NONO_c72250(fgd)
NSR: NS506_01163(fgd1)
NTP: CRH09_37790(fgd)
RER: RER_14710(fdg)
REY: O5Y_06970
ROP: ROP_19180(fdg)
REQ: REQ_39220
RHB: NY08_4549
RFA: A3L23_02644(fgd_2)
RHS: A3Q41_00717(fgd_1)
RRZ: CS378_09650(fgd)
RHU: A3Q40_00093(fgd1_1)
RQI: C1M55_07460(fgd)
RRT: 4535765_03876(fgd1_4) 4535765_04398(fgd)
GBR: Gbro_4404
GOC: CXX93_05015(fgd)
GIT: C6V83_17875(fgd)
TPR: Tpau_3763
SRT: Srot_0132
DIT: C3V38_03570(fgd)
DIZ: CT688_14145(fgd)
MTS: MTES_1878
AGM: DCE93_13670(fgd)
MYL: C3E77_13165(fgd)
SALC: C2138_12560(fgd)
HUM: DVJ78_03025(fgd)
BCV: Bcav_1687
LMOI: VV02_19860
ORN: DV701_08880(fgd)
KFL: Kfla_0290
NML: Namu_0967
KRA: Krad_3294
AMD: AMED_3381
AMN: RAM_17200
AMM: AMES_3342
AMZ: B737_3342
AOI: AORI_3107(zwf)
AJA: AJAP_23830(fgd)
AMYC: CU254_17095(fgd) CU254_21825(fgd)
PDX: Psed_3151
PSEE: FRP1_10925
PSEH: XF36_10660
SESP: BN6_24600(fgd1)
ACTI: UA75_09630
ACAD: UA74_09660
AHG: AHOG_09035(fgd2)
ACTA: C1701_20095(fgd)
ASE: ACPL_6651(fdg)
ACTN: L083_6206(fdg)
AFS: AFR_31800
ACTS: ACWT_6521
MMA: MM_2195
MMAC: MSMAC_1949
MTHE: MSTHC_0689
MTHR: MSTHT_0039
MPY: Mpsy_0793
MPD: MCP_1470(fgd)
RCI: RCIX1283(fgd-1) RRC242(fgd-2)
SALI: L593_11930
NEV: NTE_02717
TAA: NMY3_01705(fgd1_3) NMY3_01719(fgd1_4)
 » show all
Taxonomy
Reference
1  [PMID:8631674]
  Authors
Purwantini E, Daniels L
  Title
Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis.
  Journal
J Bacteriol 178:2861-6 (1996)
DOI:10.1128/JB.178.10.2861-2866.1996
  Sequence
Reference
2  [PMID:17376702]
  Authors
Bashiri G, Squire CJ, Baker EN, Moreland NJ
  Title
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis  expression system.
  Journal
Protein Expr Purif 54:38-44 (2007)
DOI:10.1016/j.pep.2007.01.014
  Sequence
[mtu:Rv0407]
Reference
3  [PMID:8997717]
  Authors
Purwantini E, Gillis TP, Daniels L
  Title
Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea.
  Journal
FEMS Microbiol Lett 146:129-34 (1997)
DOI:10.1111/j.1574-6968.1997.tb10182.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.98.2
IUBMB Enzyme Nomenclature: 1.1.98.2
ExPASy - ENZYME nomenclature database: 1.1.98.2
BRENDA, the Enzyme Database: 1.1.98.2

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