KEGG   ENZYME: 1.1.99.14Help
Entry
EC 1.1.99.14                Enzyme                                 

Name
glycolate dehydrogenase;
glycolate oxidoreductase;
glycolic acid dehydrogenase;
glycolate:(acceptor) 2-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors
BRITE hierarchy
Sysname
glycolate:acceptor 2-oxidoreductase
Reaction(IUBMB)
glycolate + acceptor = glyoxylate + reduced acceptor [RN:R00476]
Reaction(KEGG)
Substrate
glycolate [CPD:C00160];
acceptor [CPD:C00028]
Product
glyoxylate [CPD:C00048];
reduced acceptor [CPD:C00030]
Comment
Also acts on (R)-lactate. 2,6-Dichloroindophenol and phenazine methosulfate can act as acceptors.
History
EC 1.1.99.14 created 1978
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:4557653]
  Authors
Lord JM.
  Title
Glycolate oxidoreductase in Escherichia coli.
  Journal
Biochim Biophys Acta 267:227-37 (1972)
DOI:10.1016/0005-2728(72)90111-9
Other DBs
ExplorEnz - The Enzyme Database: 1.1.99.14
IUBMB Enzyme Nomenclature: 1.1.99.14
ExPASy - ENZYME nomenclature database: 1.1.99.14
BRENDA, the Enzyme Database: 1.1.99.14
CAS: 37368-32-4

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