KEGG   ENZYME: 1.1.99.4Help
Entry
EC 1.1.99.4                 Enzyme                                 

Name
dehydrogluconate dehydrogenase;
ketogluconate dehydrogenase;
alpha-ketogluconate dehydrogenase;
2-keto-D-gluconate dehydrogenase;
2-oxogluconate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors
BRITE hierarchy
Sysname
2-dehydro-D-gluconate:acceptor 2-oxidoreductase
Reaction(IUBMB)
2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced acceptor [RN:R07153]
Reaction(KEGG)
Substrate
2-dehydro-D-gluconate [CPD:C06473];
acceptor [CPD:C00028]
Product
2,5-didehydro-D-gluconate [CPD:C02780];
reduced acceptor [CPD:C00030]
Comment
A flavoprotein.
History
EC 1.1.99.4 created 1961, modified 1989
Reference
1  [PMID:13395514]
  Authors
DATTA AG, KATZNELSON H.
  Title
The oxidation of 2-ketogluconate by a partially purified enzyme from Acetobactor melanogenum.
  Journal
Arch Biochem Biophys 65:576-8 (1956)
DOI:10.1016/0003-9861(56)90218-1
Reference
2
  Authors
Shinagawa, E. and Ameyama, M.
  Title
2-Keto-D-gluconate dehydrogenase from Gluconobacter melanogenus, membrane-bound.
  Journal
Methods Enzymol 89:194-198 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.99.4
IUBMB Enzyme Nomenclature: 1.1.99.4
ExPASy - ENZYME nomenclature database: 1.1.99.4
BRENDA, the Enzyme Database: 1.1.99.4
CAS: 9028-82-4

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