KEGG   ENZYME: 1.13.11.36Help
Entry
EC 1.13.11.36               Enzyme                                 

Name
chloridazon-catechol dioxygenase;
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (ring-opening)
Reaction(IUBMB)
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone [RN:R04602]
Reaction(KEGG)
Substrate
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone [CPD:C04798];
O2 [CPD:C00007]
Product
5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone [CPD:C05155]
Comment
An iron protein, requiring additional Fe2+. Not identical with EC 1.13.11.1 (catechol 1,2-dioxygenase), EC 1.13.11.2 (catechol 2,3-dioxygenase) or EC 1.13.11.5 (homogentisate 1,2-dioxygenase). Involved in the breakdown of the herbicide chloridazon.
History
EC 1.13.11.36 created 1984
Reference
1  [PMID:19349]
  Authors
Muller R, Haug S, Eberspacher J, Lingens F.
  Title
[Catechol 2,3-dioxygenase from pyrazon-degrading bacteria (author's transl)]
  Journal
Hoppe Seylers Z Physiol Chem 358:797-805 (1977)
Reference
2  [PMID:6811270]
  Authors
Muller R, Schmitt S, Lingens F.
  Title
A novel non-heme iron-containing dioxygenase. Chloridazon-catechol dioxygenase from Phenylobacterium immobilis DSM 1986.
  Journal
Eur J Biochem 125:579-84 (1982)
DOI:10.1111/j.1432-1033.1982.tb06722.x
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.36
IUBMB Enzyme Nomenclature: 1.13.11.36
ExPASy - ENZYME nomenclature database: 1.13.11.36
BRENDA, the Enzyme Database: 1.13.11.36
CAS: 82869-32-7

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