KEGG   ENZYME: 1.13.11.37Help
Entry
EC 1.13.11.37               Enzyme                                 

Name
hydroxyquinol 1,2-dioxygenase;
hydroxyquinol dioxygenase;
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing);
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (ring-opening)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
hydroxyquinol:oxygen 1,2-oxidoreductase (ring-opening)
Reaction(IUBMB)
hydroxyquinol + O2 = maleylacetate [RN:R04061]
Reaction(KEGG)
R04061;
(other) R03891
Show
Substrate
hydroxyquinol [CPD:C02814];
O2 [CPD:C00007]
Product
maleylacetate [CPD:C02222]
Comment
An iron protein. Highly specific; catechol and pyrogallol are acted on at less than 1% of the rate at which hydroxyquinol is oxidized.
History
EC 1.13.11.37 created 1989, modified 2013
Pathway
ec00361  Chlorocyclohexane and chlorobenzene degradation
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04098  hydroxyquinol 1,2-dioxygenase
Genes
KMI: VW41_06390
CEM: LH23_12110
CEN: LH86_11520
PPUN: PP4_21440
PFE: PSF113_2031(pcpA)
PPSL: BJP27_05915
GAI: IMCC3135_30335(chqB)
HCS: FF32_04235
HAK: KO116_02895
HAM: HALO2442
HBE: BEI_0308(chqB)
REH: H16_B0968(pcpA)
CNC: CNE_BB1p03460(tcpC) CNE_BB1p12870(pcpA)
CGD: CR3_2773(chqB)
BCJ: BCAL1342
BCEO: I35_1237
BAM: Bamb_3333
BCED: DM42_367(chqB)
BCON: NL30_08950
BSEM: WJ12_06615
PSPU: NA29_21265
POL: Bpro_2064
AAA: Acav_4141
VEI: Veis_4613
LCH: Lcho_0834
SMI: BN406_06712(chqB)
BJA: bll2679
BRS: S23_46820
AOL: S58_16190
BRAD: BF49_1393
AZC: AZC_1414
MNO: Mnod_0748
PHL: KKY_96
OTM: OSB_07930(chqB)
AHT: ANTHELSMS3_00943(chqB)
SPHK: SKP52_13005(chqB)
SWI: Swit_4890
STAX: MC45_16620
SINB: SIDU_09280
MVA: Mvan_4404
CGL: NCgl2951(Cgl3056)
CGB: cg3385(catA3)
CGU: WA5_1113 WA5_2951(CatA3)
CGT: cgR_2941
CGM: cgp_1311 cgp_3385(catA3)
CGJ: AR0_14800
CGY: CGLY_10700(chqB)
CDX: CDES_03625(chqB)
ROP: ROP_42970
RFA: A3L23_03379(npcC)
SBH: SBI_00376
SLE: sle_04030(sle_04030)
PSIM: KR76_25510
BSD: BLASA_2968(chqB2)
AMN: RAM_24710
AMM: AMES_4795(catA)
AMZ: B737_4795(catA)
PSEA: WY02_04130
ACTN: L083_5615
CAI: Caci_4340
 » show all
Taxonomy
Reference
1  [PMID:6539772]
  Authors
Sze IS, Dagley S.
  Title
Properties of salicylate hydroxylase and hydroxyquinol 1,2-dioxygenase purified from Trichosporon cutaneum.
  Journal
J Bacteriol 159:353-9 (1984)
Reference
2  [PMID:15772073]
  Authors
Ferraroni M, Seifert J, Travkin VM, Thiel M, Kaschabek S, Scozzafava A, Golovleva L, Schlomann M, Briganti F
  Title
Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex  3E, a key enzyme involved in polychlorinated aromatics biodegradation.
  Journal
J Biol Chem 280:21144-54 (2005)
DOI:10.1074/jbc.M500666200
  Sequence
Reference
3  [PMID:16232466]
  Authors
Hatta T, Nakano O, Imai N, Takizawa N, Kiyohara H
  Title
Cloning and sequence analysis of hydroxyquinol 1,2-dioxygenase gene in 2,4,6-trichlorophenol-degrading Ralstonia pickettii DTP0602 and characterization  of its product.
  Journal
J Biosci Bioeng 87:267-72 (1999)
DOI:10.1016/S1389-1723(99)80030-9
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.37
IUBMB Enzyme Nomenclature: 1.13.11.37
ExPASy - ENZYME nomenclature database: 1.13.11.37
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.37
BRENDA, the Enzyme Database: 1.13.11.37
CAS: 91847-14-2

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