KEGG   ENZYME: 1.13.11.6Help
Entry
EC 1.13.11.6                Enzyme                                 

Name
3-hydroxyanthranilate 3,4-dioxygenase;
3-hydroxyanthranilate oxygenase;
3-hydroxyanthranilic acid oxygenase;
3-hydroxyanthranilic oxygenase;
3-hydroxyanthranilic acid oxidase;
3HAO;
3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (ring-opening)
Reaction(IUBMB)
3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde [RN:R02665]
Reaction(KEGG)
Substrate
3-hydroxyanthranilate [CPD:C00632];
O2 [CPD:C00007]
Product
2-amino-3-carboxymuconate semialdehyde [CPD:C04409]
Comment
Requires Fe2+.
History
EC 1.13.11.6 created 1965 as EC 1.13.1.6, transferred 1972 to EC 1.13.11.6
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K00452  3-hydroxyanthranilate 3,4-dioxygenase
Genes
HSA: 23498(HAAO)
PTR: 737730(HAAO)
PPS: 100996154(HAAO)
GGO: 101148006(HAAO)
PON: 100450425(HAAO)
NLE: 100597867(HAAO)
MCC: 713101(HAAO)
MCF: 102146559(HAAO)
CSAB: 103220394(HAAO)
RRO: 104677535(HAAO)
RBB: 108513224(HAAO)
CJC: 100387677(HAAO)
SBQ: 101036618(HAAO)
MMU: 107766(Haao)
RNO: 56823(Haao)
CGE: 100759566(Haao)
NGI: 103736390(Haao)
HGL: 101717713(Haao)
CCAN: 109681242(Haao)
OCU: 100351818(HAAO)
TUP: 102475852(HAAO)
CFA: 611728(HAAO)
AML: 100474771(HAAO)
UMR: 103671196(HAAO)
ORO: 101381063(HAAO)
FCA: 101092928(HAAO)
PTG: 102949867(HAAO)
AJU: 106976955(HAAO)
BTA: 510602(HAAO)
BOM: 102286028(HAAO)
PHD: 102323310(HAAO)
CHX: 102187775(HAAO)
OAS: 101115197(HAAO)
SSC: 100514283(HAAO)
CFR: 102506534(HAAO)
CDK: 105103547(HAAO)
BACU: 103015991(HAAO)
LVE: 103072062(HAAO)
OOR: 101281384(HAAO)
ECB: 100053689(HAAO)
EPZ: 103558402(HAAO)
EAI: 106826383(HAAO)
MYB: 102258008(HAAO)
MYD: 102757787(HAAO)
HAI: 109385560(HAAO)
RSS: 109456388(HAAO)
PALE: 102895649(HAAO)
LAV: 100659363(HAAO)
TMU: 101354384
MDO: 100033379(HAAO)
SHR: 100928599(HAAO)
OAA: 100078929
GGA: 421396(HAAO)
MGP: 100543137(HAAO)
CJO: 107311195(HAAO)
APLA: 101795577(HAAO)
ACYG: 106031489(HAAO)
TGU: 100229666(HAAO)
GFR: 102044213(HAAO)
FAB: 101810284(HAAO)
PHI: 102102942(HAAO)
PMAJ: 107202479(HAAO)
CCW: 104685671(HAAO)
FPG: 101919252(HAAO)
FCH: 102047459(HAAO)
CLV: 102083931(HAAO)
EGZ: 104128748(HAAO)
AAM: 106490387(HAAO)
ASN: 102377804(HAAO)
AMJ: 102570322(HAAO)
PSS: 102447289(HAAO)
CMY: 102930437
CPIC: 101945388(HAAO)
ACS: 100552208(haao)
PVT: 110087895(HAAO)
PBI: 103049607(HAAO)
GJA: 107114052(HAAO)
XLA: 398998(haao.L)
XTR: 448761(haao)
NPR: 108784948(HAAO)
DRE: 492518(haao)
CCAR: 109065483 109105318(haao)
IPU: 100529041(haao)
AMEX: 103021885(haao)
TRU: 101074031(haao)
LCO: 104925901(haao)
NCC: 104948631(haao)
MZE: 101478224(haao)
OLA: 101157240(haao)
XMA: 102217485(haao)
PRET: 103477324(haao)
NFU: 107375526(haao)
CSEM: 103386899(haao)
LCF: 108895730(haao)
HCQ: 109523036(haao)
BPEC: 110154512(haao)
SASA: 100196450(haao)
ELS: 105029925(haao)
SFM: 108942619(haao)
LCM: 102348971(HAAO)
CMK: 103177992(haao)
CIN: 100175986
SPU: 582154
APLC: 110988911
SKO: 100372516
TUT: 107366985
CEL: CELE_K06A4.5(haao-1)
CBR: CBG19288
CRG: 105319341
MYI: 110456269
LAK: 106152037
EPA: 110231310
ADF: 107341440
HMG: 100203279
SCE: YJR025C(BNA1)
ERC: Ecym_7384
TPF: TPHA_0A04890(TPHA0A04890)
TDL: TDEL_0E05010(TDEL0E05010)
PIC: PICST_76205(BNA1)
CAL: CAALFM_CR05440WA(CaO19.3515)
CAUR: QG37_01272
NCR: NCU03282
MGR: MGG_00549
MAW: MAC_08136
CMT: CCM_02219
MBE: MBM_04804
ANG: ANI_1_1110144(An16g08210)
PBL: PAAG_11922(PAAG_04757)
ABE: ARB_06509
PTE: PTT_17358
CNE: CNB05620
CNB: CNBB0170
ABP: AGABI1DRAFT77052(AGABI1DRAFT_77052)
ABV: AGABI2DRAFT189007(AGABI2DRAFT_189007)
DDI: DDB_G0282743(haao)
DFA: DFA_10991(haao)
SMIN: v1.2.015275.t1(symbB.v1.2.015275.t1)
NGR: NAEGRDRAFT_65213(AM29)
XCC: XCC1555(haaO)
XCB: XC_2679
XCP: XCR_1834
XCV: XCV1645
XAX: XACM_1575
XAC: XAC1603(haaO)
XCI: XCAW_02721(haaO)
XOO: XOO2424(haaO)
XOM: XOO2302(XOO2302)
XOP: PXO_00755
XOR: XOC_1833
XAL: XALC_1752
XPH: XppCFBP6546_18300(XppCFBP6546P_18300)
SML: Smlt3159(nbaC)
SMT: Smal_2597
SMZ: SMD_2736(nbaC)
SACZ: AOT14_22780(nbaC)
PSUW: WQ53_15020
PSD: DSC_08475
LAB: LA76x_2545(nbaC)
LAQ: GLA29479_1096(nbaC)
LCP: LC55x_2797(nbaC)
LGU: LG3211_2669(nbaC)
LEZ: GLE_2675(nbaC)
LEM: LEN_2360
DKO: I596_659
PCQ: PcP3B5_23530(nbaC)
PSOS: POS17_2258
PSET: THL1_487
SWD: Swoo_1408
KKO: Kkor_0380
KGE: TQ33_1986
RIN: ACS15_4680(nbaC)
RME: Rmet_5193
BUT: X994_5943
BCJ: BCAM2130(nbaC)
BCEO: I35_6012(nbaC)
BMUL: NP80_3864(nbaC)
BFN: OI25_252(nbaC)
PPNO: DA70_24000
PPNM: LV28_06705
PPUL: RO07_00745
PSPU: NA29_10880
PAPI: SG18_00960
AXY: AXYL_05542(nbaC)
PUT: PT7_3611
POL: Bpro_5139
MXA: MXAN_0919
AMIH: CO731_02610(nbaC)
OAN: Oant_4402
OAH: DR92_3842(nbaC)
SIL: SPO1774
JAN: Jann_1447
SMAZ: LH19_00760
SGI: SGRAN_3549(nbaC)
SWI: Swit_3523
SPKC: KC8_11585
SPHD: HY78_06665
BCA: BCE_2151
BCX: BCA_2149(nbaC)
BCF: bcf_10185
BCER: BCK_24250
BTL: BALH_1838
BMYC: DJ92_4632(nbaC)
BMQ: BMQ_3593(nbaC)
BMD: BMD_3578(nbaC)
BMEG: BG04_467(nbaC)
GTN: GTNG_3157(nbaC)
REY: O5Y_02275
REQ: REQ_05070
KFL: Kfla_5491
SRO: Sros_9110
SAQ: Sare_3897
MIL: ML5_3360
GES: VT84_05915(nbaC)
CHU: CHU_3382(nbaC)
HSW: Hsw_0109
GFO: GFO_3400
GFL: GRFL_1507
FJO: Fjoh_1221
FJG: BB050_01403(nbaC)
FPS: FP2235(haaO)
FBR: FBFL15_0559(haaO)
FIN: KQS_12965(haaO)
ZPR: ZPR_0297
MARM: YQ22_07065
CBAL: M667_03940
CBAT: M666_03885
DOK: MED134_09816(haaO)
DDO: I597_0732(nbaC)
ZGA: ZOBELLIA_1477(nbaC)
MLT: VC82_1217
NDO: DDD_1705
POM: MED152_12779(haaO)
MYR: MYRA21_1076(nbaC)
MPW: MPR_3602
WIN: WPG_2041
TJE: TJEJU_1419(nbaC)
TMAR: MARIT_1049(nbaC)
AALG: AREALGSMS7_01032(nbaC)
 » show all
Taxonomy
Reference
1  [PMID:13884755]
  Authors
DECKER RH, KANG HH, LEACH FR, HENDERSON LM.
  Title
Purification and properties of 3-hydroxyanthranilic acid oxidase.
  Journal
J Biol Chem 236:3076-82 (1961)
Reference
2
  Authors
Hayaishi, O.
  Title
Direct oxygenation by O2, oxygenases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 8, Academic Press, New York, 1963, p. 353-371.
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.6
IUBMB Enzyme Nomenclature: 1.13.11.6
ExPASy - ENZYME nomenclature database: 1.13.11.6
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.6
BRENDA, the Enzyme Database: 1.13.11.6
CAS: 9029-50-9

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