KEGG   ENZYME: 1.13.11.61Help
Entry
EC 1.13.11.61               Enzyme                                 

Name
linolenate 9R-lipoxygenase;
NspLOX;
(9R)-LOX;
linoleate 9R-dioxygenase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
alpha-linolenate:oxygen (9R)-oxidoreductase
Reaction(IUBMB)
alpha-linolenate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate [RN:R09810]
Reaction(KEGG)
Substrate
alpha-linolenate [CPD:C06427];
O2 [CPD:C00007]
Product
(9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate [CPD:C19936]
Comment
In cyanobacteria the enzyme is involved in oxylipin biosynthesis. The enzyme also converts linoleate to (9R,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate.
History
EC 1.13.11.61 created 2011
Orthology
K18031  linolenate 9R-lipoxygenase
Genes
AMR: AM1_2589
ANA: all8020
Taxonomy
Reference
1  [PMID:20043865]
  Authors
Jerneren F, Hoffmann I, Oliw EH
  Title
Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus.
  Journal
Arch Biochem Biophys 495:67-73 (2010)
DOI:10.1016/j.abb.2009.12.022
Reference
2  [PMID:18439634]
  Authors
Andreou AZ, Vanko M, Bezakova L, Feussner I
  Title
Properties of a mini 9R-lipoxygenase from Nostoc sp. PCC 7120 and its mutant forms.
  Journal
Phytochemistry 69:1832-7 (2008)
DOI:10.1016/j.phytochem.2008.03.002
Reference
3  [PMID:18031288]
  Authors
Lang I, Gobel C, Porzel A, Heilmann I, Feussner I
  Title
A lipoxygenase with linoleate diol synthase activity from Nostoc sp. PCC 7120.
  Journal
Biochem J 410:347-57 (2008)
DOI:10.1042/BJ20071277
  Sequence
[ana:all8020]
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.61
IUBMB Enzyme Nomenclature: 1.13.11.61
ExPASy - ENZYME nomenclature database: 1.13.11.61
BRENDA, the Enzyme Database: 1.13.11.61

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