KEGG   ENZYME: 1.13.11.70Help
Entry
EC 1.13.11.70               Enzyme                                 

Name
all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase;
CCD8 (gene name);
MAX4 (gene name);
NCED8 (gene name);
all-trans-10'-apo-beta-carotenal:O2 oxidoreductase (13,14-cleaving)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
all-trans-10'-apo-beta-carotenal:oxygen oxidoreductase (13,14-cleaving)
Reaction(IUBMB)
all-trans-10'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial [RN:R10560]
Reaction(KEGG)
Substrate
all-trans-10'-apo-beta-carotenal [CPD:C20695];
O2 [CPD:C00007]
Product
13-apo-beta-carotenone [CPD:C20696];
(2E,4E,6E)-4-methylocta-2,4,6-trienedial [CPD:C20697]
Comment
Requires Fe2+. The enzyme from the plant Arabidopsis thaliana also catalyses EC 1.13.11.69, carlactone synthase, 10-fold faster.
History
EC 1.13.11.70 created 2012
Orthology
K17913  carlactone synthase / all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase
Genes
ATH: AT4G32810(CCD8)
ALY: ARALYDRAFT_353547
CRB: 17880263
CSAT: 104716888 104721542 104729987
EUS: EUTSA_v10024788mg
BRP: 103850421
BNA: 106371158 106372794 106375326
BOE: 106297618 106329062
THJ: 104820078
CPAP: 110825785
TCC: 18587976
DZI: 111285387
GMX: 100794831(CCD8) 100814148
VRA: 106761448
VAR: 108321824
CCAJ: 109799996
CAM: 101497957
LJA: Lj0g3v0335089.1(Lj0g3v0335089.1) Lj1g3v2068760.1(Lj1g3v2068760.1)
ADU: 107470782
AIP: 107623923
LANG: 109339284
FVE: 101301466
PPER: 18789175
PMUM: 103320239
PAVI: 110761281
ZJU: 107420451
CSV: 101216826
CMO: 103488182(CCD8)
MCHA: 111004996
CMOS: 111462801
RCU: 8275656
JCU: 105638200
HBR: 110648761
VVI: 100250765
SLY: 101254620
SPEN: 107028115
SOT: 102595155
CANN: 107839011
NTA: 107812793(MAX4) 107821949
NSY: 104228402
NTO: 104117083
INI: 109179896
DCR: 108215310
BVG: 104885388
SOE: 110787413
NNU: 104592092
OSA: 4326177
DOSA: Os01t0566500-01(Os01g0566500) Os01t0746400-00(Os01g0746400)
OBR: 102709984
BDI: 100831734
ATS: 109738648(LOC109738648) 109753493(LOC109753493) 109753519(LOC109753519) 109758391(LOC109758391)
ZMA: 100502522(CCD8)
DCT: 110092372
AOF: 109842452
SMO: SELMODRAFT_127411(MAX4-2) SELMODRAFT_173016(MAX4-1)
PPP: 112283943
MNG: MNEG_9548
 » show all
Taxonomy
Reference
1  [PMID:15342640]
  Authors
Schwartz SH, Qin X, Loewen MC
  Title
The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching.
  Journal
J Biol Chem 279:46940-5 (2004)
DOI:10.1074/jbc.M409004200
  Sequence
[ath:AT4G32810]
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.70
IUBMB Enzyme Nomenclature: 1.13.11.70
ExPASy - ENZYME nomenclature database: 1.13.11.70
BRENDA, the Enzyme Database: 1.13.11.70

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