KEGG   ENZYME: 1.13.12.1Help
Entry
EC 1.13.12.1                Enzyme                                 

Name
arginine 2-monooxygenase;
arginine monooxygenase;
arginine decarboxylase;
arginine oxygenase (decarboxylating);
arginine decarboxy-oxidase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
BRITE hierarchy
Sysname
L-arginine:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O [RN:R00559]
Reaction(KEGG)
Substrate
L-arginine [CPD:C00062];
O2 [CPD:C00007]
Product
4-guanidinobutanamide [CPD:C03078];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Comment
A flavoprotein. Also acts on canavanine and homoarginine.
History
EC 1.13.12.1 created 1972
Pathway
ec00330  Arginine and proline metabolism
Reference
1  [PMID:4295160]
  Authors
Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV.
  Title
[Arginine oxygenase (decarboxylating). V. Purification and flavin nature]
  Journal
Biochim Biophys Acta 151:353-66 (1968)
DOI:10.1016/0005-2744(68)90102-2
Reference
2  [PMID:14479405]
  Authors
NGUYEN-VAN-THOAI, OLOMUCKI A
  Title
[Arginine decarboxyoxidase. I. Characteristics and nature of the enzyme].
  Journal
Biochim Biophys Acta 59:533-44 (1962)
DOI:10.1016/0006-3002(62)90631-5
Reference
3  [PMID:14479406]
  Authors
NGUYEN-VAN-THOAI, OLOMUCKI A
  Title
[Arginine decarboxyoxidase. II. Oxidation of canavanine and homoarginine to beta-guanidoxy-propionamide and delta-guanidovaleramide].
  Journal
Biochim Biophys Acta 59:545-52 (1962)
DOI:10.1016/0006-3002(62)90632-7
Other DBs
ExplorEnz - The Enzyme Database: 1.13.12.1
IUBMB Enzyme Nomenclature: 1.13.12.1
ExPASy - ENZYME nomenclature database: 1.13.12.1
BRENDA, the Enzyme Database: 1.13.12.1
CAS: 9027-36-5

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