KEGG   ENZYME: 1.14.11.13Help
Entry
EC 1.14.11.13               Enzyme                                 

Name
gibberellin 2beta-dioxygenase;
gibberellin 2beta-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
BRITE hierarchy
Sysname
(gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)
Reaction(IUBMB)
gibberellin 1 + 2-oxoglutarate + O2 = 2beta-hydroxygibberellin 1 + succinate + CO2 [RN:R03008]
Reaction(KEGG)
Substrate
gibberellin 1 [CPD:C00859];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007]
Product
2beta-hydroxygibberellin 1 [CPD:C03579];
succinate [CPD:C00042];
CO2 [CPD:C00011]
Comment
Also acts on a number of other gibberellins.
History
EC 1.14.11.13 created 1990
Pathway
ec00904  Diterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K04125  gibberellin 2beta-dioxygenase
Genes
ATH: AT1G02400(GA2OX6) AT1G30040(GA2OX2) AT1G47990(GA2OX4) AT1G50960(GA2OX7) AT1G78440(ATGA2OX1) AT2G34555(ATGA2OX3) AT4G21200(GA2OX8)
ALY: ARALYDRAFT_314235(ATGA2OX4) ARALYDRAFT_316746 ARALYDRAFT_473223 ARALYDRAFT_482417(ATGA2OX3) ARALYDRAFT_658002 ARALYDRAFT_672610 ARALYDRAFT_677832 ARALYDRAFT_682146
CRB: 17879009 17889792 17893555 17895174 17897166 17897766 17898674 17898739
CSAT: 104705216 104713527 104718211 104727877 104731425 104738722 104741593 104743113 104743933 104744037 104746059 104751742 104751743 104751744 104754212 104758090 104758394 104759752 104767569 104777710 104779288 104784176 104788997 104792207 109127259
EUS: EUTSA_v10008120mg EUTSA_v10008179mg EUTSA_v10012193mg EUTSA_v10012337mg EUTSA_v10017806mg EUTSA_v10018871mg EUTSA_v10021102mg EUTSA_v10027367mg
BRP: 103828910 103832324 103832325 103834198 103835241 103836654 103840439(BrGA2ox2) 103844588 103853128 103857700 103858857 103861222 103865345 103867444 103868596 103868699
BNA: 106345169 106357323 106357377 106357378 106357909 106361601 106364683 106370917 106375617 106375947 106375948 106395019 106395633 106398038 106398652 106401876 106404190 106404899 106406425 106420935 106421107 106422184 106422838 106422857 106427738 106432781 106433741 106435076 106438344 106440311 106441804 106443099 106444436 106450284 111198555 111204737 111213455 111216046
BOE: 106293773 106293978 106294685 106296799 106298976 106302200 106304863 106319842 106325334 106329405 106331044 106333093 106333439 106333615 106338045 106340820 106340921
THJ: 104808080 104812500 104814299 104814693 104817884 104820648 104821802 104825932
CPAP: 110806753 110807626 110810948 110812577 110819492 110821505
VAR: 108319893 108325599(VaGA2oxB3) 108328736(VaGA2oxB1) 108332455(VaGA2oxA2) 108332851 108333021 108333577 108338898(VaGA2oxB2) 108339477 108341762(VaGA2oxA1) 108347858(VaGA2oxC1)
LJA: Lj0g3v0081939.1(Lj0g3v0081939.1) Lj0g3v0081939.2(Lj0g3v0081939.2) Lj0g3v0099859.1(Lj0g3v0099859.1) Lj0g3v0281419.1(Lj0g3v0281419.1) Lj0g3v0322199.1(Lj0g3v0322199.1) Lj1g3v0052430.1(Lj1g3v0052430.1) Lj3g3v0421660.1(Lj3g3v0421660.1) Lj3g3v1015420.1(Lj3g3v1015420.1) Lj3g3v1541300.1(Lj3g3v1541300.1) Lj3g3v3500200.1(Lj3g3v3500200.1) Lj4g3v0254300.1(Lj4g3v0254300.1) Lj4g3v2253520.1(Lj4g3v2253520.1) Lj6g3v0216910.1(Lj6g3v0216910.1) Lj6g3v1945170.1(Lj6g3v1945170.1)
CSV: 101205466 101214915(GA2ox3) 101215016(GA2ox4) 101215638 101215820(GA2ox1) 101217885(GA2ox2) 101220719(GA2ox5) 101220829
VVI: 100244543(GA2ox2) 100245189(GA2ox2) 100248356(GA2ox1) 100248676(GA2ox1) 100258599(GA2ox4) 100258946(GA2ox6) 100264177(GA2ox3) 100854674(GA2ox4)
DOSA: Os01t0209700-01(Os01g0209700) Os01t0332200-01(Os01g0332200) Os01t0757200-01(Os01g0757200) Os02t0630300-01(Os02g0630300) Os04t0522500-01(Os04g0522500) Os05t0208550-00(Os05g0208550) Os05t0514600-01(Os05g0514600) Os05t0560900-01(Os05g0560900) Os07t0103500-01(Os07g0103500)
ATS: 109742727(LOC109742727) 109744166(LOC109744166) 109746245(LOC109746245) 109751037(LOC109751037) 109756419(LOC109756419) 109759536(LOC109759536) 109761426(LOC109761426) 109765316(LOC109765316) 109773801(LOC109773801) 109779071(LOC109779071) 109782553(LOC109782553) 109782554(LOC109782554) 109785020(LOC109785020) 109785292(LOC109785292) 109785294(LOC109785294)
PPP: 112278537
PIC: PICST_51972(GBD1)
 » show all
Taxonomy
Reference
1  [PMID:24241725]
  Authors
Smith VA, Macmillan J
  Title
The partial purification and characterisation of gibberellin 2beta-hydroxylases from seeds of Pisum sativum.
  Journal
Planta 167:9-18 (1986)
DOI:10.1007/BF00446362
Other DBs
ExplorEnz - The Enzyme Database: 1.14.11.13
IUBMB Enzyme Nomenclature: 1.14.11.13
ExPASy - ENZYME nomenclature database: 1.14.11.13
BRENDA, the Enzyme Database: 1.14.11.13
CAS: 85713-20-8

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