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Entry
EC 1.14.11.15               Enzyme                                 

Name
gibberellin 3beta-dioxygenase;
gibberellin 3beta-hydroxylase;
(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
BRITE hierarchy
Sysname
(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)
Reaction(IUBMB)
gibberellin 20 + 2-oxoglutarate + O2 = gibberellin 1 + succinate + CO2 [RN:R03009]
Reaction(KEGG)
R03009;
(other) R06336
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Substrate
gibberellin 20 [CPD:C02035];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007]
Product
gibberellin 1 [CPD:C00859];
succinate [CPD:C00042];
CO2 [CPD:C00011]
Comment
Requires Fe2+ and ascorbate.
History
EC 1.14.11.15 created 1992
Pathway
ec00904  Diterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K04124  gibberellin 3beta-dioxygenase
Genes
ATH: AT1G15550(GA3OX1) AT1G80330(GA3OX4) AT1G80340(GA3OX2) AT4G21690(GA3OX3)
ALY: ARALYDRAFT_316927(ATGA3OX4) ARALYDRAFT_354612(ATGA3OX3) ARALYDRAFT_471756 ARALYDRAFT_677611 ARALYDRAFT_920152
CRB: 17880948 17895899 17896335 17899159
CSAT: 104714346 104714348 104718161 104722885 104731370 104740245 104752489 104754057 104755873 104774302
EUS: EUTSA_v10008008mg EUTSA_v10019663mg EUTSA_v10019816mg EUTSA_v10026853mg
BRP: 103832494 103834178 103842895 103853267 103853269 103872350
BNA: 106351318 106364556 106364558 106378169 106398539 106398553 106414646 106432150 106436778 106436779 111206537
BOE: 106293027 106311184 106325906 106326604 106334026
THJ: 104799656 104808214 104812480 104812481
CPAP: 110811373 110818550 110818551 110824725
LJA: Lj0g3v0086189.1(Lj0g3v0086189.1) Lj0g3v0106889.1(Lj0g3v0106889.1) Lj0g3v0106899.1(Lj0g3v0106899.1) Lj0g3v0109249.1(Lj0g3v0109249.1) Lj1g3v1929130.1(Lj1g3v1929130.1) Lj3g3v2247040.1(Lj3g3v2247040.1)
CSV: 101219147(GA3ox3) 101219385 101219623 101222387(GA3ox4) 101222627(GA3ox2) 101223012(Cs3OH1)
VVI: 100249739(GA3ox2) 100265167(GA3ox1) 100267924(GA3ox1)
DOSA: Os01t0177400-01(Os01g0177400) Os05t0178100-01(Os05g0178100)
ATS: 109769159(LOC109769159)
AOF: 109835859
ATR: 18424978
SMO: SELMODRAFT_450789(GA3ox-1) SELMODRAFT_450793(GA3ox-2)
 » show all
Taxonomy
Reference
1
  Authors
Kwak, S.-S., Kamiya, Y., Sakurai, A., Takahishi, N. and Graebe, J.E.
  Title
Partial-purification and characterization of gibberellin 3beta-hydroxylase from immature seeds of Phaseolus vulgaris L.
  Journal
Plant Cell Physiol 29:935-943 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 1.14.11.15
IUBMB Enzyme Nomenclature: 1.14.11.15
ExPASy - ENZYME nomenclature database: 1.14.11.15
BRENDA, the Enzyme Database: 1.14.11.15
CAS: 120860-89-1

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