KEGG   ENZYME: 1.14.13.107Help
Entry
EC 1.14.13.107              Enzyme                                 

Name
limonene 1,2-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
limonene,NAD(P)H:oxygen oxidoreductase
Reaction(IUBMB)
(1) (S)-limonene + NAD(P)H + H+ + O2 = 1,2-epoxymenth-8-ene + NAD(P)+ + H2O [RN:R09385 R09389];
(2) (R)-limonene + NAD(P)H + H+ + O2 = 1,2-epoxymenth-8-ene + NAD(P)+ + H2O [RN:R06398 R09393]
Reaction(KEGG)
Substrate
(S)-limonene;
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007];
(R)-limonene
Product
1,2-epoxymenth-8-ene;
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
A flavoprotein (FAD). Limonene is the most widespread terpene and is formed by more than 300 plants. Rhodococcus erythropolis DCL14, a Gram-positive bacterium, is able to grow on both (S)-limonene and (R)-limonene as the sole source of carbon and energy. NADPH can act instead of NADH, although more slowly. It has not been established if the product formed is optically pure or a mixture of two enantiomers.
History
EC 1.14.13.107 created 2009
Pathway
ec00903  Limonene and pinene degradation
Orthology
K14733  limonene 1,2-monooxygenase
Genes
MES: Meso_3721
PLA: Plav_1646
RBS: RHODOSMS8_02624(limB)
BJA: bll0895
BJU: BJ6T_09070
BJP: RN69_04430
BRA: BRADO0508
BBT: BBta_7675
BRS: S23_69110
AOL: S58_71450
BRAD: BF49_7289
RBM: TEF_06950
PZU: PHZ_c1133
RDE: RD1_3871
RLI: RLO149_c005640(limB)
SPHM: G432_04655
SSY: SLG_34780
MTU: Rv3618
MTV: RVBD_3618
MTC: MT3720
MRA: MRA_3654
MTUR: CFBS_3834
MTD: UDA_3618
MTUC: J113_25305
MTUE: J114_19330
MTUL: TBHG_03556
MTUT: HKBT1_3819
MTUU: HKBT2_3827
MLP: MLM_2061
MUL: MUL_2949
MMC: Mmcs_4772
MKM: Mkms_4858
MJL: Mjls_5158
MMI: MMAR_2824
MHAD: B586_04220
MVA: Mvan_1925
MGI: Mflv_4429
MPHL: MPHLCCUG_00069(limB_1)
MVQ: MYVA_1767
MTHN: 4412656_02907(limB_3) 4412656_04146(limB_7)
MAB: MAB_0527c
MABB: MASS_0495
MCHE: BB28_02480
MSTE: MSTE_00475
MTER: 4434518_03775(limB_5)
NCY: NOCYR_3944(limB)
NSR: NS506_03939(limB)
RER: RER_46450
REY: O5Y_21925
ROP: ROP_46710(limB)
REQ: REQ_44050
SCO: SCP1.240c(mmyO)
SCT: SCAT_0119(limB)
SBH: SBI_00943
SHY: SHJG_4007
SALS: SLNWT_0923
SALU: DC74_7652
SLX: SLAV_32745(limB7)
SFK: KY5_6779
NAL: B005_2518(limB)
GOB: Gobs_2267
BSD: BLASA_2848(limB) BLASA_3512(limB2)
MMAR: MODMU_2453(limB)
PDX: Psed_5126
PSEA: WY02_18195
PSEH: XF36_23280
SESP: BN6_21310(limB)
AYM: YM304_25770(limB)
 » show all
Taxonomy
Reference
1  [PMID:10224006]
  Authors
van der Werf MJ, Swarts HJ, de Bont JA.
  Title
Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.
  Journal
Appl Environ Microbiol 65:2092-102 (1999)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.107
IUBMB Enzyme Nomenclature: 1.14.13.107
ExPASy - ENZYME nomenclature database: 1.14.13.107
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.13.107
BRENDA, the Enzyme Database: 1.14.13.107

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