KEGG   ENZYME: 1.14.13.168Help
Entry
EC 1.14.13.168              Enzyme                                 

Name
indole-3-pyruvate monooxygenase;
YUC2 (gene name);
spi1 (gene name)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
indole-3-pyruvate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
Reaction(IUBMB)
(indol-3-yl)pyruvate + NADPH + H+ + O2 = (indol-3-yl)acetate + NADP+ + H2O + CO2 [RN:R10181]
Reaction(KEGG)
Substrate
(indol-3-yl)pyruvate [CPD:C00331];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
(indol-3-yl)acetate [CPD:C00954];
NADP+ [CPD:C00006];
H2O [CPD:C00001];
CO2 [CPD:C00011]
Comment
This plant enzyme, along with EC 2.6.1.99 L-tryptophan---pyruvate aminotransferase, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.
History
EC 1.14.13.168 created 2012
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K11816  indole-3-pyruvate monooxygenase
Genes
RSS: 109440938
ATH: AT1G04180(YUC9) AT1G04610(YUC3) AT1G21430(YUC11) AT1G48910(YUC10) AT2G33230(YUC7) AT4G13260(YUC2) AT4G28720(YUC8) AT4G32540(YUC1) AT5G11320(YUC4) AT5G25620(YUC6) AT5G43890(YUC5)
ALY: ARALYDRAFT_311505 ARALYDRAFT_313035 ARALYDRAFT_314320 ARALYDRAFT_332994 ARALYDRAFT_353573 ARALYDRAFT_470444 ARALYDRAFT_487963 ARALYDRAFT_491885 ARALYDRAFT_494616 ARALYDRAFT_669072 ARALYDRAFT_910627
CRB: 17876898 17878451 17879290 17880436 17884096 17884232 17890020 17897566 17898846 17898965 17900166
CSAT: 104700128 104705397 104706887 104716924 104717321 104719136 104721575 104721998 104723876 104725065 104730018 104730458 104732463 104735146 104736590 104738933 104738984 104742424 104743435 104754546 104754599 104758187 104759333 104760565 104761814 104769354 104771046 104771539 104777806 104778559 104778809 104786252 104786573
EUS: EUTSA_v10003214mg EUTSA_v10004282mg EUTSA_v10009484mg EUTSA_v10009764mg EUTSA_v10010013mg EUTSA_v10012211mg EUTSA_v10016084mg EUTSA_v10017688mg EUTSA_v10025272mg EUTSA_v10025326mg EUTSA_v10026965mg
BRP: 103827945 103834554 103834745(FMO) 103837094 103843640 103843665 103844236 103844281 103846731 103848845 103850766 103850830 103854158 103854740 103867554 103871436 103872978 103874420
BNA: 106348545 106352498 106359798 106359824 106364745 106365401 106365409 106365896 106369419 106370091 106371275 106372416 106372559 106374221 106375177 106375577 106379806 106383033 106386407 106395116 106399583 106399876 106403755 106405007 106406214 106407352 106409809 106413796 106433672 106440374 106442956 106454718 111199934 111207578
BOE: 106293311 106293797 106294414 106299667 106300234 106302128 106304772 106310347 106310789 106310829 106313990 106316934 106322981 106326734 106328282 106334045 106341046 106343643
THJ: 104799208 104801114 104804031 104807030 104807031 104808762 104814541 104815035 104816013 104820064 104820418 104824740 104824743 104826104
LJA: Lj0g3v0049159.1(Lj0g3v0049159.1) Lj0g3v0049349.1(Lj0g3v0049349.1) Lj0g3v0085899.1(Lj0g3v0085899.1) Lj0g3v0101099.1(Lj0g3v0101099.1) Lj0g3v0147119.1(Lj0g3v0147119.1) Lj0g3v0147129.1(Lj0g3v0147129.1) Lj0g3v0162379.1(Lj0g3v0162379.1) Lj0g3v0241619.1(Lj0g3v0241619.1) Lj0g3v0308259.1(Lj0g3v0308259.1) Lj0g3v0308259.2(Lj0g3v0308259.2) Lj1g3v2036560.1(Lj1g3v2036560.1) Lj1g3v4528740.1(Lj1g3v4528740.1) Lj1g3v4764550.1(Lj1g3v4764550.1) Lj1g3v4764680.2(Lj1g3v4764680.2) Lj1g3v4764680.3(Lj1g3v4764680.3) Lj3g3v3189630.1(Lj3g3v3189630.1) Lj3g3v3189640.1(Lj3g3v3189640.1) Lj4g3v3081700.1(Lj4g3v3081700.1) Lj6g3v0044630.1(Lj6g3v0044630.1)
FVE: 101295199 101305359(YUC4)
CMO: 103483530 103488201(YUC6) 103488266(YUC4) 103488697(YUC11) 103489823(YUC5) 103498935(YUC8) 103499731 103500125(YUC12) 103501555(YUC2)
DOSA: Os01t0224700-01(Os01g0224700) Os01t0273800-01(Os01g0273800) Os01t0274100-00(Os01g0274100) Os01t0645400-01(Os01g0645400) Os01t0732700-01(Os01g0732700) Os02t0272200-00(Os02g0272200) Os03t0162000-01(Os03g0162000) Os04t0128900-01(Os04g0128900) Os05t0528600-01(Os05g0528600) Os07t0437000-01(Os07g0437000) Os11t0207700-00(Os11g0207700) Os11t0207900-00(Os11g0207900) Os12t0189500-00(Os12g0189500) Os12t0512000-01(Os12g0512000)
ATS: 109733044(LOC109733044) 109735032(LOC109735032) 109737167(LOC109737167) 109739288(LOC109739288) 109740135(LOC109740135) 109748795(LOC109748795) 109748800(LOC109748800) 109751227(LOC109751227) 109751403(LOC109751403) 109755251(LOC109755251) 109760867(LOC109760867) 109763705(LOC109763705) 109764689(LOC109764689) 109770592(LOC109770592) 109771922(LOC109771922) 109776896(LOC109776896) 109777467(LOC109777467) 109783187 109784014(LOC109784014)
 » show all
Taxonomy
Reference
1  [PMID:22025724]
  Authors
Mashiguchi K, Tanaka K, Sakai T, Sugawara S, Kawaide H, Natsume M, Hanada A, Yaeno T, Shirasu K, Yao H, McSteen P, Zhao Y, Hayashi K, Kamiya Y, Kasahara H
  Title
The main auxin biosynthesis pathway in Arabidopsis.
  Journal
Proc Natl Acad Sci U S A 108:18512-7 (2011)
DOI:10.1073/pnas.1108434108
  Sequence
Reference
2  [PMID:22155950]
  Authors
Zhao Y
  Title
Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants.
  Journal
Mol Plant 5:334-8 (2012)
DOI:10.1093/mp/ssr104
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.168
IUBMB Enzyme Nomenclature: 1.14.13.168
ExPASy - ENZYME nomenclature database: 1.14.13.168
BRENDA, the Enzyme Database: 1.14.13.168

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