KEGG   ENZYME: 1.14.13.46Help
Entry
EC 1.14.13.46               Enzyme                                 

Name
(-)-menthol monooxygenase;
l-menthol monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)
Reaction(IUBMB)
(-)-menthol + NADPH + H+ + O2 = p-menthane-3,8-diol + NADP+ + H2O [RN:R02178]
Reaction(KEGG)
Substrate
(-)-menthol [CPD:C00400];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
p-menthane-3,8-diol [CPD:C02904];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
History
EC 1.14.13.46 created 1992
Reference
1  [PMID:2906604]
  Authors
Madyastha KM, Srivatsan V.
  Title
Studies on the metabolism of l-menthol in rats.
  Journal
Drug Metab Dispos 16:765-72 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.46
IUBMB Enzyme Nomenclature: 1.14.13.46
ExPASy - ENZYME nomenclature database: 1.14.13.46
BRENDA, the Enzyme Database: 1.14.13.46
CAS: 117590-75-7

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