KEGG   ENZYME: 1.16.9.1Help
Entry
EC 1.16.9.1                 Enzyme                                 

Name
iron:rusticyanin reductase;
Cyc2
Class
Oxidoreductases;
Oxidizing metal ions;
With a copper protein as acceptor
BRITE hierarchy
Sysname
Fe(II):rusticyanin oxidoreductase
Reaction(IUBMB)
Fe(II) + rusticyanin = Fe(III) + reduced rusticyanin
Substrate
Fe(II) [CPD:C14818];
rusticyanin
Product
Fe(III) [CPD:C14819];
reduced rusticyanin
Comment
Contains c-type heme. The enzyme in Acidithiobacillus ferrooxidans is a component of an electron transfer chain from Fe(II), comprising this enzyme, the copper protein rusticyanin, cytochrome c4, and cytochrome c oxidase (EC 1.9.3.1).
History
EC 1.16.9.1 created 2011 as EC 1.16.98.1, transferred 2011 to EC 1.16.9.1
Orthology
K20150  iron:rusticyanin reductase
Genes
AFE: Lferr_2751
AFR: AFE_3153(cyc2)
AFI: Acife_1872
Taxonomy
Reference
1  [PMID:8049223]
  Authors
Blake RC 2nd, Shute EA
  Title
Respiratory enzymes of Thiobacillus ferrooxidans. Kinetic properties of an acid-stable iron:rusticyanin oxidoreductase.
  Journal
Biochemistry 33:9220-8 (1994)
Reference
2  [PMID:9809418]
  Authors
Appia-Ayme C, Bengrine A, Cavazza C, Giudici-Orticoni MT, Bruschi M, Chippaux M, Bonnefoy V
  Title
Characterization and expression of the co-transcribed cyc1 and cyc2 genes encoding the cytochrome c4 (c552) and a high-molecular-mass cytochrome c from Thiobacillus ferrooxidans ATCC 33020.
  Journal
FEMS Microbiol Lett 167:171-7 (1998)
DOI:10.1111/j.1574-6968.1998.tb13224.x
  Sequence
Reference
3  [PMID:11741873]
  Authors
Yarzabal A, Brasseur G, Ratouchniak J, Lund K, Lemesle-Meunier D, DeMoss JA, Bonnefoy V
  Title
The high-molecular-weight cytochrome c Cyc2 of Acidithiobacillus ferrooxidans is  an outer membrane protein.
  Journal
J Bacteriol 184:313-7 (2002)
DOI:10.1128/JB.184.1.313-317.2002
Reference
4  [PMID:15256554]
  Authors
Yarzabal A, Appia-Ayme C, Ratouchniak J, Bonnefoy V
  Title
Regulation of the expression of the Acidithiobacillus ferrooxidans rus operon encoding two cytochromes c, a cytochrome oxidase and rusticyanin.
  Journal
Microbiology 150:2113-23 (2004)
DOI:10.1099/mic.0.26966-0
Reference
5  [PMID:18791023]
  Authors
Taha TM, Kanao T, Takeuchi F, Sugio T
  Title
Reconstitution of iron oxidase from sulfur-grown Acidithiobacillus ferrooxidans.
  Journal
Appl Environ Microbiol 74:6808-10 (2008)
DOI:10.1128/AEM.00787-08
Reference
6  [PMID:18632666]
  Authors
Castelle C, Guiral M, Malarte G, Ledgham F, Leroy G, Brugna M, Giudici-Orticoni MT
  Title
A new iron-oxidizing/O2-reducing supercomplex spanning both inner and outer membranes, isolated from the extreme acidophile Acidithiobacillus ferrooxidans.
  Journal
J Biol Chem 283:25803-11 (2008)
DOI:10.1074/jbc.M802496200
Reference
7  [PMID:19703284]
  Authors
Quatrini R, Appia-Ayme C, Denis Y, Jedlicki E, Holmes DS, Bonnefoy V
  Title
Extending the models for iron and sulfur oxidation in the extreme acidophile Acidithiobacillus ferrooxidans.
  Journal
BMC Genomics 10:394 (2009)
DOI:10.1186/1471-2164-10-394
Other DBs
ExplorEnz - The Enzyme Database: 1.16.9.1
IUBMB Enzyme Nomenclature: 1.16.9.1
ExPASy - ENZYME nomenclature database: 1.16.9.1
BRENDA, the Enzyme Database: 1.16.9.1

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