KEGG   ENZYME: 1.2.1.13Help
Entry
EC 1.2.1.13                 Enzyme                                 

Name
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
triosephosphate dehydrogenase (NADP+);
dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
NADP+-glyceraldehyde-3-phosphate dehydrogenase;
NADP+-glyceraldehyde phosphate dehydrogenase;
NADP+-dependent glyceraldehyde phosphate dehydrogenase;
NADP+-triose phosphate dehydrogenase;
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
GAPDH
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)
Reaction(IUBMB)
D-glyceraldehyde 3-phosphate + phosphate + NADP+ = 3-phospho-D-glyceroyl phosphate + NADPH + H+ [RN:R01063]
Reaction(KEGG)
Substrate
D-glyceraldehyde 3-phosphate [CPD:C00118];
phosphate [CPD:C00009];
NADP+ [CPD:C00006]
Product
3-phospho-D-glyceroyl phosphate [CPD:C00236];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.13 created 1961
Pathway
ec00710  Carbon fixation in photosynthetic organisms
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05298  glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
Genes
ATH: AT1G12900(GAPA-2) AT1G42970(GAPB) AT3G26650(GAPA)
ALY: ARALYDRAFT_471443 ARALYDRAFT_473747(GAPB) ARALYDRAFT_484431
CRB: 17885995 17897550 17898235
CSAT: 104710464 104739945 104755567 104757901 104771836 104777631 104779875
EUS: EUTSA_v10004217mg EUTSA_v10004349mg EUTSA_v10007809mg
BRP: 103833307(GAPDH-B) 103843097(GAPDH-A) 103871970(BcGAPDH) 103875281
BNA: 106346458 106349325 106361259 106367141 106400587 106400630 106400839 106405503 106409666 106412548
BOE: 106295615 106305800 106308443 106311773 106319595
THJ: 104805297 104813182 104825726
CPAP: 110813067 110818294
LJA: Lj1g3v3385810.2(Lj1g3v3385810.2) Lj1g3v3943580.1(Lj1g3v3943580.1)
CANN: 107851146(gapB) 107866774 107870368(gapA1) 107877699(gapA2)
DOSA: Os03t0129300-01(Os03g0129300)
ATS: 109754470(LOC109754470) 109783816(LOC109783816)
ZMA: 103641723 103642790 542290(gpb1) 542368(gpa1)
CRE: CHLREDRAFT_129019(GAP3)
MIS: MICPUN_104695(GAPB) MICPUN_104876(GAPA)
MPP: MICPUCDRAFT_25339(GAPDH_5) MICPUCDRAFT_49403(GAPDH_3)
APRO: F751_4740
 » show all
Taxonomy
Reference
1  [PMID:13804190]
  Authors
BRENNEMAN FN, VOLK WA.
  Title
Glyceraldehyde phosphate dehydrogenase activity with triphosphopyridine nucleotide and with diphosphopyridine nucleotide.
  Journal
J Biol Chem 234:2443-7 (1959)
Reference
2
  Authors
Gibbs, M.
  Title
TPN triosephosphate dehydrogenase from plant tissue.
  Journal
Methods Enzymol 1:411-415 (1955)
Reference
3  [PMID:13271400]
  Authors
ROSENBERG LL, ARNON DI.
  Title
The preparation and properties of a new glyceraldehyde-3-phosphate dehydrogenase from photosynthetic tissues.
  Journal
J Biol Chem 217:361-71 (1955)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.13
IUBMB Enzyme Nomenclature: 1.2.1.13
ExPASy - ENZYME nomenclature database: 1.2.1.13
BRENDA, the Enzyme Database: 1.2.1.13
CAS: 37250-87-6

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