KEGG   ENZYME: 1.2.1.32Help
Entry
EC 1.2.1.32                 Enzyme                                 

Name
aminomuconate-semialdehyde dehydrogenase;
2-aminomuconate semialdehyde dehydrogenase;
2-hydroxymuconic acid semialdehyde dehydrogenase;
2-hydroxymuconate semialdehyde dehydrogenase;
alpha-aminomuconic epsilon-semialdehyde dehydrogenase;
alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase;
2-hydroxymuconic semialdehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase
Reaction(IUBMB)
2-aminomuconate 6-semialdehyde + NAD+ + H2O = 2-aminomuconate + NADH + 2 H+ [RN:R03889]
Reaction(KEGG)
Substrate
2-aminomuconate 6-semialdehyde [CPD:C03824];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
2-aminomuconate [CPD:C02220];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts on 2-hydroxymuconate semialdehyde.
History
EC 1.2.1.32 created 1972
Pathway
ec00380  Tryptophan metabolism
Orthology
K10217  aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
Genes
PGE: LG71_12245
SLQ: M495_05225
PSD: DSC_09155
LAB: LA76x_2548(aldH8A1)
LAQ: GLA29479_1093
LCP: LC55x_2794(aldH8A1)
LGU: LG3211_2666(aldh8a1)
LEZ: GLE_2672
LEM: LEN_2363
LMB: C9I47_1501
DKO: I596_481
PPSE: BN5_3621(xylG)
PCQ: PcP3B5_23470(amnC)
PPI: ND088(nahI)
PKC: PKB_3261(amnc1) PKB_3609(amnc3)
PSOS: POS17_2264
PSET: THL1_493
AVN: Avin_08730(xylG) Avin_30620(lapC)
AVL: AvCA_08730(xylG) AvCA_30620(lapC)
AVD: AvCA6_08730(xylG) AvCA6_30620(lapC)
ACX: Achr_32710(xylG)
SWD: Swoo_1410
MAD: HP15_1111(betB) HP15_4032(betB)
SALH: HMF8227_02739(dmpC)
CYQ: Q91_0507(xylG) Q91_1784(lapC)
APAC: S7S_06985
KKO: Kkor_0387
KGE: TQ33_1983
TBN: TBH_C0927
RSO: RSp0890(dmpC)
RSE: F504_4327
RPI: Rpic_4622
REH: H16_B0547(h16_B0547)
CNC: CNE_2c04930(dmpC) CNE_BB1p12000(dmpC1) CNE_BB1p13290(dmpC2)
RME: Rmet_1322(dmpC) Rmet_5206(amnC)
BCJ: BCAM2132(nbaE)
BCEN: DM39_4835
BCEO: I35_6014(nbaE)
BMUL: NP80_3862
BCT: GEM_5404
BCED: DM42_4994
BCON: NL30_24605
BTEI: WS51_00555
BPSL: WS57_12170
BXE: Bxe_A1147(amnC)
BXB: DR64_3306
BFN: OI25_258
BAV: BAV0552(amnC)
BHZ: ACR54_00824(amnC_1)
AXX: ERS451415_05308(amnC)
PUT: PT7_3613
POL: Bpro_5132
AJS: Ajs_0220
VEI: Veis_2787
MPT: Mpe_A2275
JAG: GJA_237
LCH: Lcho_3354
AZO: azo1852(lapC) azo2435(nahI)
ARC: ABLL_2445
MXA: MXAN_0921
CCX: COCOR_00871(amnC)
BBAC: EP01_17230
ARA: Arad_7263(betB)
MSL: Msil_1476
NAR: Saro_3855
SMAZ: LH19_00745
SGI: SGRAN_3552(amnC)
SWI: Swit_3519
SPHD: HY78_06685
SPKC: KC8_11570
SJP: SJA_C1-11860(hpaE_xylG)
SINB: SIDU_08335
TMO: TMO_b0431(dmpC)
MAGQ: MGMAQ_0648
BLI: BL03906
BLD: BLi03994(dmpC)
BCA: BCE_2154
BCX: BCA_2152
BCF: bcf_10200
BCER: BCK_24235
BTL: BALH_1841
BMYC: DJ92_4635
BMQ: BMQ_3590
BMD: BMD_3575
BMEG: BG04_464
BACO: OXB_2507
BGY: BGLY_4398
GTN: GTNG_3154(nbaE)
GGH: GHH_c14810(dmpC)
BBE: BBR47_29750(dhaS)
ASOC: CB4_02455(xylG)
AAC: Aaci_1622
AAD: TC41_1518(hpaE)
BTS: Btus_0966
TMR: Tmar_1783
SAY: TPY_0646(hpaE)
LPIL: LIP_2170
MIT: OCO_14810
MIA: OCU_15250
MJL: Mjls_4206
NFA: NFA_30520
NFR: ERS450000_01013(xylG)
REY: O5Y_02260
REQ: REQ_05040(amnC)
RRT: 4535765_01258(amnC_1) 4535765_01264(amnC_2)
GBR: Gbro_0237
SCB: SCAB_15221(amnC)
SBH: SBI_01538
KFL: Kfla_5493
TCU: Tcur_0539
SRO: Sros_9116
PDX: Psed_2510
ALL: CRK56596
SAQ: Sare_3903
MIL: ML5_3354
RCA: Rcas_2406
CAU: Caur_1356
CAG: Cagg_2038
TTJ: TTHB240
GES: VT84_03880(amnC)
HSW: Hsw_0099
DDO: I597_1376(amnC)
NDO: DDD_2048
WIN: WPG_2044
TJE: TJEJU_1410(dmpC)
TMAR: MARIT_1046(dmpC)
KOS: KORDIASMS9_02221(amnC)
MARF: CJ739_785
 » show all
Taxonomy
Reference
1  [PMID:14275130]
  Authors
ICHIYAMA A, NAKAMURA S, KAWAI H, HONJO T, NISHIZUKA Y, HAYAISHI O, SENOH S.
  Title
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
  Journal
J Biol Chem 240:740-9 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.32
IUBMB Enzyme Nomenclature: 1.2.1.32
ExPASy - ENZYME nomenclature database: 1.2.1.32
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.32
BRENDA, the Enzyme Database: 1.2.1.32
CAS: 37250-95-6

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